| Not Yet Recruiting | Construction of a Multidimensional Risk Prediction Model for Severe Early Childhood Caries NCT07335744 | The Children's Hospital of Zhejiang University School of Medicine | — |
| Recruiting | Intraoral Camera-Assisted Parent Training NCT07327060 | Aydin Adnan Menderes University | N/A |
| Not Yet Recruiting | Prevalence of Dental Caries in Patients With Dental Crowding NCT06438926 | Cairo University | — |
| Unknown | Modified Atraumatic Restorative Treatment Using CPP ACP NCT06098911 | Cairo University | N/A |
| Recruiting | Clinical Performance and Acceptance of Bioflx Crowns NCT06677983 | Hams Hamed Abdelrahman | N/A |
| Active Not Recruiting | Extraction of the Compromised First Permanent Molars NCT06231823 | Ain Shams University | N/A |
| Completed | In Situ Comparison of the Remineralization Potential of Optimized Fluoride Dentifrice With Control Fluoride De NCT06010732 | Indiana University | Phase 3 |
| Completed | Evaluation of the Anticaries Efficacy of Dentifrice Formulations Using an In-situ Model NCT06140758 | Procter and Gamble | N/A |
| Unknown | Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexic NCT05960110 | Anahuac Mayab University | Phase 3 |
| Unknown | Use Of Hall Technique In Deciduous Molars Affected By Extensive Caries Lesions NCT05301439 | University of Nove de Julho | Phase 1 / Phase 2 |
| Completed | Efficacy of an Antibacterial Toothpaste and Patients' Satisfaction NCT05569850 | University of Bologna | N/A |
| Active Not Recruiting | Trial With Two New Tooth-colored Restorative Materials in Class I/II Cavities NCT05748327 | Ivoclar Vivadent AG | N/A |
| Completed | Saliva Insulin as Biomarker of Risk Factors for Metabolic Dysregulation and Caries NCT05211843 | Jodi Stookey | N/A |
| Active Not Recruiting | Alveolar Ridge Preservation Following Tooth Extraction. NCT05505084 | University of Pennsylvania | — |
| Completed | A Strategy to Prevent the Recurrence of Dental Disease in Children Receiving Dental Treatment With General Ane NCT05212142 | Virginia Commonwealth University | N/A |
| Unknown | Antimicrobial Photodynamic Therapy as an Adjunct for Management of Deep Caries Lesions NCT05236205 | University of Nove de Julho | Phase 2 |
| Unknown | Pulpotomy in Primary Molars Treated With Premixed Bio-ceramic MTA Versus Formocresol NCT05314842 | Sarah Abdelbar Mahmoud | Phase 3 |
| Unknown | Parental Satisfaction of Hall Technique Versus SDF in the Management of Carious Primary Molars NCT05249231 | Cairo University | N/A |
| Terminated | The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth NCT05221749 | Nour Ammar, BDS | Phase 3 |
| Unknown | Comparison Between Resin Based and Glass Ionomer Based Hydrophilic Fissure Sealants NCT05127343 | Cairo University | N/A |
| Withdrawn | Endodontic-Restorative Pre-Radiation Therapy of Head and Neck Cancer Patients NCT04996641 | Abramson Cancer Center at Penn Medicine | N/A |
| Unknown | Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste NCT05109299 | Cairo University | N/A |
| Unknown | Evaluation of Caries Detection Methods NCT05064566 | Nazan Kocak Topbas | — |
| Terminated | Lithium Disilicate Crowns Study NCT05070416 | Ivoclar Vivadent AG | N/A |
| Unknown | Management of Deep Carious Lesions in Adults NCT05144711 | Jordan University of Science and Technology | N/A |
| Terminated | Clinical Evaluation of a Dental Glass Ceramic NCT04933123 | Ivoclar Vivadent AG | N/A |
| Unknown | The Efficiency and Gingival Health Status of Hall Versus SDF Techniques in the Management of Carious Primary M NCT04889196 | Sarah Abdalla Ibrahim Abdalla | Phase 3 |
| Withdrawn | Effect of the Use of Xylitol Gum in the Prevention of Caries Lesions in Children Living in Ladakh NCT04420780 | University of Bern | N/A |
| Completed | Salivary Fluoride Clearance NCT06735235 | Procter and Gamble | Phase 1 |
| Unknown | Post-operative Pain and Child Behavior of Hall Technique Versus SDF in the Management of Carious Primary Molar NCT04794426 | Noura Mohamed Alhosaini | Phase 3 |
| Active Not Recruiting | Clinical Evaluation of "Cention Forte" Restorative Material NCT04796974 | Istanbul Medipol University Hospital | N/A |
| Unknown | Effect of Enzyme-containing Mouth Rinse on Dental Biofilm in Patients With Fixed Orthodontic Appliances NCT05033015 | Malmö University | N/A |
| Completed | Evaluation of the Fluoride Dose Response Using In Situ Caries Model NCT04763044 | Procter and Gamble | Phase 4 |
| Completed | The Impact of Oral Health in HIV Patients on Antiretroviral Therapy NCT04645693 | University of Pennsylvania | — |
| Completed | Evaluation of Dentifrice Formulations to Remineralize Enamel and Dentine Subsurface Lesions in a Double-Blind NCT06140745 | Procter and Gamble | N/A |
| Unknown | Oral Health and Severe COPD NCT05311657 | Heidelberg University | — |
| Completed | Effect of Lifestyle on Caries and Apical Periodontitis NCT06072742 | University of Siena | — |
| Completed | Antibacterial Effect of Chlorhexidine Added to the Preventive Protocol in Adolescent Special Needs NCT04679558 | Cairo University | EARLY_Phase 1 |
| Unknown | Selective Caries vs Stepwise Caries Removal Technique in Deep Carious Lesions NCT04375215 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Completed | Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Ris NCT03684993 | Cairo University | Phase 2 / Phase 3 |
| Completed | The Effect of Miswak Chewing Sticks on the Oral Helicobacter Pylori Infection NCT02418520 | Kuwait University | N/A |
| Unknown | Outcome of Pulpotomy Versus Root Canal Therapy NCT05279781 | Jordan University of Science and Technology | N/A |
| Completed | Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer NCT04365270 | Ain Shams University | Phase 3 |
| Unknown | Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients NCT03656432 | Cairo University | Phase 3 |
| Terminated | Longitudinal Follow-up of High Viscosity Glassionomer IonoStar Plus Versus a Composite Bulk X-tra-Fil Combined NCT03568253 | University Hospital, Montpellier | N/A |
| Completed | Prospective, Split-mouth, Comparative Study to Compare Clinical Outcomes of Two Different Posterior Composite NCT04708223 | Ivoclar Vivadent AG | N/A |
| Completed | Quality of Life for Children With Zirconium Anteroir Crowns Versus Strip Composite Crowns NCT04973761 | Minia University | N/A |
| Completed | The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children. NCT04906291 | Università degli Studi di Sassari | N/A |
| Completed | Evaluation of the Fluoride Dose Response of a Modified In Situ Caries Model NCT03383783 | Domenick Zero | Phase 3 |
| Withdrawn | The Effects of Chlorhexidine/Thymol Varnish on Partial Denture Patient NCT02202304 | Rosa Moreno Lopez | Phase 4 |
| Unknown | Reliability of Fluorescent Camera in Diagnosis of Occlusal Carious Lesion NCT03224962 | Cairo University | — |
| Completed | Short- and Long Term Antibacterial Effects of a Single Rinse With Different Mouthwashes: a Randomized Clinical NCT05178823 | Semmelweis University | Phase 4 |
| Completed | Is DIAGNOcam Comparable to Bitewing Radiographs as a Diagnostic Method for Approximal Caries in Primary Teeth? NCT03181711 | Malmö University | — |
| Completed | Success Rate of Three Capping Materials NCT03833557 | Cairo University | N/A |
| Completed | Effectiveness of the Ozone Application in Two-Visit Indirect Pulp Therapy of Permanent Molars With Deep Cariou NCT03693066 | Izmir Katip Celebi University | N/A |
| Unknown | Diagnosis of Common Oral Diseases by Signature Volatile Profiles NCT02931032 | Hadassah Medical Organization | N/A |
| Completed | The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions NCT02953886 | Heba Mitwalli | Phase 4 |
| Unknown | Clinical Effectiveness of Embrace Wetbond and Clinpro as Pits and Fissure Sealants in Young Permanent Molars NCT02933463 | Cairo University | N/A |
| Completed | Study to Evaluate the Clinical Efficacy of Streptococcus Dentisani CECT 7746 in Caries Risk Reduction NCT03468842 | AB Biotics, SA | Phase 1 |
| Completed | Total Salivary Fluoride Concentration of Healthy Adult Subjects Following Toothbrushing With Different Formula NCT02740803 | University of Leeds | N/A |
| Completed | Dental Plaque Microbiota in Caries-free and Caries-active Children NCT03906981 | Kuwait University | — |
| Completed | Clinical Evaluation of SI-R21204 Versus Nano-hybrid Resin Composite: A Prospective Controlled Clinical Trial NCT02823769 | Istanbul Medipol University Hospital | N/A |
| Completed | Effectiveness of Silver Diamine Fluoride as a Treatment for Caries in Comparison to Traditional Restorative Te NCT02601833 | University of Michigan | Phase 3 |
| Terminated | Lesion Progression After Icon Treatment in Young Adults NCT01988337 | DMG Dental Material Gesellschaft mbH | N/A |
| Completed | Clinical Evaluation of Basic Filling Material in Class I and II Posterior Restorations NCT02763085 | Istanbul Medipol University Hospital | N/A |
| Completed | Antimicrobial Activity of Two Mouthwashes NCT02375178 | Universidade do Vale do Sapucai | N/A |
| Completed | Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent T NCT02492841 | Universidad de los Andes, Chile | Phase 2 / Phase 3 |
| Completed | Effectiveness of an ICCMS™ Caries Management Program. NCT04676230 | Universidad El Bosque, Bogotá | N/A |
| Unknown | A Clinical Evaluation of a Glass Ionomer Cement (GIC) Based Restorative System Versus Bulk Filled Resin-based NCT02479711 | Ege University | N/A |
| Completed | Efficacy of Proximal Caries Infiltration NCT01726179 | DMG Dental Material Gesellschaft mbH | N/A |
| Completed | Clinical Effectiveness of Various Professionally Applied Fluoride Prophylaxes in Groups at High Risk NCT02027922 | Medical University of Warsaw | N/A |
| Completed | Comparison of 2 Different Resin Based Filling Materials in Posterior Teeth - a Multicenter Study NCT01925040 | Heraeus Kulzer GmbH | N/A |
| Completed | Third Molar: Caries, Periodontal Desease and Quality of Life NCT06081816 | University of Nove de Julho | — |
| Completed | Third Molar: Caries, Periodontal Disease and Quality of Life NCT04024644 | University of Sao Paulo | — |
| Completed | Cold Plasma for Dental Restoration and Caries Prevention NCT01529606 | Nanova, Inc | N/A |
| Completed | An in Situ Study on the Impact of Fluoride Dose and Concentration in Milk on Its Anti-caries Efficacy NCT01665911 | Frank Lippert | N/A |
| Completed | In-situ Evaluation of Anti-caries Technology NCT01650493 | Solventum US LLC | — |
| Completed | Anti-caries Potential of a Sodium Monofluorophosphate and Calcium Sodium Phosphosilicate Dentifrice NCT01657877 | GlaxoSmithKline | Phase 2 |
| Completed | Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study NCT01601145 | Università degli Studi di Sassari | Phase 4 |
| Completed | Using Motivational Interviewing To Reduce Parental Risk-Related Behaviors For Early Childhood Caries NCT04286256 | University of Minnesota | N/A |
| Completed | Effectiveness of Toothbrushing Techniques in Plaque Removal and Caries Lesion Control NCT01501357 | University of Sao Paulo | N/A |
| Terminated | Electrical and Formocresol Pulpotomy in Primary Molars NCT01622153 | University Hospitals Cleveland Medical Center | N/A |
| Completed | Randomized Trial on Resin Infiltration in Deciduous Teeth NCT01881100 | Medical University of Warsaw | N/A |
| Completed | Acid Production in Dental Plaque After Exposure to Probiotic Bacteria NCT01700712 | University of Copenhagen | N/A |
| Completed | Clinical Follow Up of a Fissure Sealant Placed With Different Adhesive Protocols: 2-Year Randomized Split Mout NCT02998814 | Hacettepe University | N/A |
| Completed | School-based Oral Health Education Program Using Experiential Learning NCT02320162 | Matina Angelopoulou | N/A |
| Completed | In Situ Caries Model of Fluoride Toothpastes NCT01005966 | GlaxoSmithKline | Phase 3 |
| Completed | Oral Health Care Early Intervention Project NCT00793507 | University of Colorado, Denver | N/A |
| Completed | Improving Oral Health With Serious Games NCT02027597 | University of Washington | N/A |
| Completed | In Situ Caries Efficacy of Fluoride Toothpastes NCT00708097 | GlaxoSmithKline | Phase 3 |
| Completed | Fluoride Concentration in Inter-proximal Fluid From Dental Sealants NCT01588210 | Università degli Studi di Sassari | N/A |
| Completed | In Situ Caries of Fluoride Toothpastes NCT00708123 | GlaxoSmithKline | Phase 3 |
| Unknown | Assessment of a New Resin-based Composite Filling Material NCT00738647 | University of Aarhus | N/A |
| Unknown | a Clinical Study.the Effect of Addition of Insoluble Antibacterial Nanoparticles(IABN) in Resin Base Provision NCT00502606 | Hadassah Medical Organization | — |
| Unknown | Technique for Localization of Caries Associated Bacteria on Tooth Surfaces. NCT00421577 | Hadassah Medical Organization | — |
| Unknown | Evaluation of the Dental Health Condition in Obesity Patients Before and After Bariatric Surgery NCT00531154 | Hadassah Medical Organization | — |
| Withdrawn | Effectiveness of Two Sealant Materials Over 5 Years NCT01710865 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |