| Not Yet Recruiting | 3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Seve NCT05265052 | 3D Medicines | Phase 2 |
| Not Yet Recruiting | Evaluation of the Effects of Traditional and E-Learning Methods in Cancer Pain Care Education on Learning Outc NCT07461974 | Bilecik Seyh Edebali Universitesi | N/A |
| Not Yet Recruiting | Enhancing Pain Management Among Patients Diagnosed With Stage III and Stage IV of Breast Cancer: The Power of NCT07497451 | Middle East University | N/A |
| Not Yet Recruiting | Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer Pain NCT07489625 | Qinghai Red Cross Hospital | EARLY_Phase 1 |
| Not Yet Recruiting | MRI Evaluation of Spinal Cord Edema After CT-Guided Percutaneous Cordotomy in Cancer Pain Patients NCT07400055 | Mersin University | — |
| Not Yet Recruiting | Intermittent Erector Spinae Plane Block Via Subcutaneous Port for Cancer Pain NCT07396558 | Hanoi Medical University | N/A |
| Recruiting | A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain NCT07447856 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Recruiting | Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer Pain NCT07445386 | Ankara Etlik City Hospital | N/A |
| Recruiting | Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy NCT07405645 | University of Virginia | N/A |
| Not Yet Recruiting | Assessing Hydromorphone Sustained-Release Tablets in Elderly Cancer Pain Patients With Renal Insufficiency NCT07421674 | Taian Cancer Hospital | — |
| Withdrawn | Development of a Cloud-Based PRO (Patient-Reported Outcome) Management Program for Home-Based Cancer Pain Care NCT07308223 | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | N/A |
| Not Yet Recruiting | UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients NCT07265492 | Hospital de Manises | — |
| Not Yet Recruiting | Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic NCT06644573 | Nyree Penn | Phase 1 |
| Recruiting | Effect of Adding Ultrasound Guided IPACK Block to Adductor Canal Block for Postoperative Pain in Knee Tumor Ex NCT07382297 | National Cancer Institute, Egypt | N/A |
| Not Yet Recruiting | e-Natureza Blue Care: Nature-based Virtual Reality and Pain Perception NCT07053228 | Hospital Israelita Albert Einstein | N/A |
| Recruiting | Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN) NCT07318519 | Medstar Health Research Institute | N/A |
| Active Not Recruiting | Unique Treatment of Oncology Pain in Advanced Cancer NCT06533657 | ZYUS Life Sciences Inc. | Phase 2 |
| Not Yet Recruiting | Neurolytic Block Techniques In Abdominal Visceral Cancer Pain NCT06978673 | Instituto do Cancer do Estado de São Paulo | N/A |
| Recruiting | Refining mUltiple Artificial intelliGence strateGies for Automatic Pain Assessment Investigations: RUGGI Study NCT07038434 | Valentina Cerrone | N/A |
| Enrolling By Invitation | Effect of Transcutaneous Electrical Nerve Stimulation or Acupressure on Pain in Patients With Head and Neck Ca NCT07051265 | Kaohsiung Veterans General Hospital. | N/A |
| Not Yet Recruiting | Effectiveness of the Digital Multimedia Health Education in Improving Cancer Pain, Analgesic Adherence, and Pa NCT06791213 | National Taiwan University Hospital | N/A |
| Recruiting | Opioid Misuse in Patients with Cancer NCT06489769 | Rigshospitalet, Denmark | — |
| Not Yet Recruiting | The Effect of Patient-Controlled TEAS vs Sham TEAS for Improve Quality of Life in Patients With Cancer Pain NCT06188286 | Yi Liang | N/A |
| Recruiting | Virtual Reality Therapy for Cancer-Treatment Associated Symptoms NCT06248216 | University of Maryland, Baltimore | N/A |
| Recruiting | A Randomized Controlled Trial of a Web-based Platform for Cancer Pain Management NCT06663956 | West China Hospital | Phase 2 |
| Recruiting | Meditation With Virtual Reality for Cancer Pain Relief in the Pain Therapy and Palliative Care Service NCT06328751 | Emily Santos Montarroyos | N/A |
| Completed | Reiki Therapy to Improve Key Symptoms in Integrative Oncology Clinic (REIKI) NCT06354049 | Case Comprehensive Cancer Center | N/A |
| Not Yet Recruiting | Effects of Su Jok Seed Therapy Application on Pain, Anxiety and Psychological Resilience in Patients Hospitali NCT06532175 | Muş Alparslan University | N/A |
| Recruiting | Perineal Massage in Women With Gynecological Cancer NCT06432998 | University of Alcala | N/A |
| Recruiting | Evaluation of the Medical Service by Socio-aesthetics in Oncology NCT06035731 | Centre Hospitalier de Valence | N/A |
| Recruiting | Phase I Study of sss40 Injection for Moderate-to-Severe Bone Metastatic Cancer Pain NCT07008703 | Shenyang Sunshine Pharmaceutical Co., LTD. | Phase 1 / Phase 2 |
| Recruiting | Optimizing Subcutaneous FEntanyl titRation: RApid Achievement of Adequate Exposure When Treating Cancer-Relate NCT06498037 | Erasmus Medical Center | Phase 4 |
| Recruiting | Cancer Pain Management Using a Web-based Intervention NCT06085313 | University of Texas at Austin | N/A |
| Completed | 35kDa Hyaluronan Fragment Treatment of Colorectal and Rectal Cancer NCT06209970 | Nakhia Impex LLC | N/A |
| Unknown | TEAS for the Treatment of Pain in Bone Metastases of Lung Cancer NCT05730972 | The Third Affiliated hospital of Zhejiang Chinese Medical University | N/A |
| Unknown | Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds NCT05800834 | Instituto Nacional de Cancer, Brazil | Phase 2 |
| Completed | The Effectiveness of Battlefield Acupuncture (BFA) With Standard Therapy in Gynecological Cancer Pain NCT06115330 | Indonesia University | N/A |
| Completed | The Effectiveness of Electroacupuncture and Standard Therapy Compared to Standard Therapy in Gynecological Can NCT06073496 | Indonesia University | N/A |
| Completed | Effectiveness of Manual Acupuncture and Standard Therapy Compared to Standard Therapy in Gynecological Cancer NCT06070363 | Indonesia University | N/A |
| Unknown | Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC NCT05272865 | LaSanta S A S | Phase 1 / Phase 2 |
| Completed | Efficacy of Biofeedback-Based Serious Game for Pain Alleviation in Middle-Aged and Older Ovarian Cancer Patien NCT06612489 | Shanghai Jiao Tong University School of Medicine | N/A |
| Completed | Pilot Trial of an Online Pain Coping Skills Training Program in Spanish NCT05917171 | Wake Forest University Health Sciences | N/A |
| Completed | Clinical Classification of Pain in Breast Cancer Survivors NCT04219072 | Kutahya Health Sciences University | — |
| Completed | Randomized Controlled Trial of Virtual Reality Assisted Guided Imagery (VRAGI) for Pain in Advanced Cancer Pat NCT05348174 | Prisma Health-Upstate | N/A |
| Unknown | Real World Study of Oxycodone Sustained-release Tablets for Patients With Moderate to Severe Cancer Pain NCT05962294 | Henan Cancer Hospital | — |
| Active Not Recruiting | Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief NCT05877521 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain NCT05774197 | University of Oklahoma | N/A |
| Recruiting | Implementation of Personalized Medicine for Optimal Drug Therapy in Cancer NCT05830279 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Unknown | Treatment Efficacy of Mindfulness-based Cognitive Therapy for Distress in Advanced Cancer Patients NCT05768256 | CHA University | N/A |
| Completed | Correlation Between the Analgesic Effect of Fentanyl Transdermal Patches and Nutritional Status in Cancer Pain NCT06369961 | Chongqing University Cancer Hospital | — |
| Unknown | Effectiveness of a Pain Neuroscience Education Program in Adults With Cancer Pain NCT05581784 | Instituto Neurociencia Del Dolor | N/A |
| Unknown | Home Management of Simple Hydromorphone PCA Pump Mode NCT05744089 | The First Affiliated Hospital of Xinxiang Medical College | N/A |
| Completed | The Effect Of Mandala Activity On Postoperative Pain And Anxiety Levels In Gynecological Oncology Patients NCT06590389 | Istanbul University - Cerrahpasa | N/A |
| Unknown | Telemedicine Improves Pain-related Disabilities in Following up Cancer Pain Outpatient NCT05628246 | Mahidol University | N/A |
| Completed | Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain NCT05674240 | Wake Forest University Health Sciences | — |
| Unknown | Coeliac Plexus Neurolysis Versus Splanchnic Nerve Neurolysis NCT05541211 | The University of Hong Kong | N/A |
| Withdrawn | Proportional Dose of Sublingual Fentanyl Tablet Based on Daily Opioid Requirement NCT05053308 | Seoul National University | N/A |
| Unknown | Early Treatment With Invasive Technique in Cancer Pain Management NCT05594459 | Regina Elena Cancer Institute | N/A |
| Recruiting | Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement NCT05506878 | Jacques E. Chelly | N/A |
| Completed | Treatment of Cancer Pain Using an Implantable Intrathecal Pump NCT07427888 | Institute of Oncology Ljubljana | N/A |
| Withdrawn | Methadone for 'Adenocarcinopathic' Pain Treatment NCT05325164 | Ottawa Hospital Research Institute | Phase 3 |
| Completed | Virtual Reality for Outpatient Cancer Pain Management NCT05442866 | Medstar Health Research Institute | N/A |
| Completed | Early Interventional Treatment for Cancer Pain NCT05366413 | Dana-Farber Cancer Institute | N/A |
| Completed | Intraoperative Aromatherapy Versus Placebo for Port-a-Cath Placement Under Monitored Anesthesia Care. A Random NCT05328973 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Clinical Pharmacists' Intervention on Pain Management in Cancer Patients NCT05021393 | Monash University Malaysia | N/A |
| Completed | Efficacy of Duloxetine in Conjunction With Tramadol for Chronic Cancer Pain NCT05311774 | Assiut University | N/A |
| Completed | Improving Cancer Pain Management Through Teach-Back Educational Approach for Patients and Primary Caregivers: NCT05856292 | Tarumanagara University | N/A |
| Completed | Real-life Observational Study of Cancer Pain Management With Methadone NCT05265442 | RECORDATI GROUP | — |
| Completed | Assessment of Updated Educational Materials for Instanyl® NCT04938440 | Takeda | — |
| Completed | The Effect of Acupressure and Reiki on Pain and Fatigue Levels NCT05473845 | Mardin Artuklu University | N/A |
| Completed | Predictive Factors of Analgesic Response in Patients With Pain Associated With Bone Metastasys NCT06777004 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Suspended | Decreasing Long-term Opioid Use in Cancer Survivors NCT05067556 | Virginia Commonwealth University | N/A |
| Unknown | Effects of Mobile Medicine on Cancer Patients NCT05049811 | Fujian Cancer Hospital | N/A |
| Completed | PARASTOP - Paracetamol With Strong Opioids NCT05051735 | Oslo University Hospital | Phase 3 |
| Recruiting | Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes NCT04907643 | Cedars-Sinai Medical Center | N/A |
| Completed | IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Succe NCT04785768 | Fujian Cancer Hospital | Phase 3 |
| Recruiting | Pain ASsessment in CAncer Patients by Machine LEarning (PASCALE) NCT04726228 | National Cancer Institute, Naples | — |
| Unknown | Transcranial Direct-current Stimulation (tDCS) Efficacy in Refractory Cancer Pain. NCT04683172 | Elsan | N/A |
| Unknown | Using Mini Program for Self-management VS Conventional Pharmaceutical Care for Cancer Pain NCT04844645 | Fujian Cancer Hospital | N/A |
| Completed | Effect of Music on Pain and Anxiety in Palliative Cancer Patients NCT07262151 | Karamanoğlu Mehmetbey University | N/A |
| Unknown | Evaluation of ESMO Guidelines Applicability and Adherence in Cancer Pain Management in the Palliative Care Set NCT04795739 | Antea Foundation | — |
| Withdrawn | Compare the Efficacy and Safety of Intranasal Esketamine in Chronic Opioid Refractory Pain NCT04666623 | University Hospital, Basel, Switzerland | Phase 2 |
| Unknown | Safety and Efficacy of Inhaled Cannabis For the Uncontrolled Pain Relief in Patients With Advanced Cancer NCT04042545 | Tetra Bio-Pharma | Phase 2 |
| Completed | Intravenous vs Oral Analgesia in Cancer Patients With Severe Pain After Successful Titration NCT04243954 | Fujian Cancer Hospital | Phase 2 |
| Completed | Retrospective Analysis of PET Brain Imaging in Chronic Cancer Pain NCT04537845 | National Taiwan University Hospital | — |
| Unknown | The Brain Metabolic Change in Chronic Cancer Pain Patient: FDG PET Image Study NCT04255628 | National Taiwan University Hospital | — |
| Completed | Permanent Celiac Plexus Block: Comparison of Pain Score in Unilateral and Bilateral Posterior Percutaneous App NCT06316908 | Sindh Institute of Urology and Transplantation | Phase 4 |
| Completed | Virtual Reality for Cancer Pain Management NCT04572074 | Medstar Health Research Institute | N/A |
| Completed | Antalgic Effects of Well-being Treatments in Cancer Care NCT05493150 | Centre Hospitalier de Valence | — |
| Completed | An Observation Study to Assess the Efficacy and Safety of Proportional Doses of Painkyl® in Patients With Brea NCT05209906 | Mackay Memorial Hospital | — |
| Active Not Recruiting | Integrative Medicine for Pain in Patients With Advanced Cancer Trial (IMPACT) NCT04095234 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Unknown | Ropivacaine/Dexamethasone and 10% Lignocaine Injection in GPN Block for Intractable Cancer Pain NCT04085120 | All India Institute of Medical Sciences | N/A |
| Unknown | Human Physiology and Self-Reported Pain Score NCT04053608 | Taichung Veterans General Hospital | — |
| Completed | Screening Tool to Identify the Dominant Pain Mechanism in Cancer Survivors: PainsCan NCT03981809 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Usefulness of Acetaminophen Associated With Strong Opioids for Acute Pain in Cancer Patients NCT04779567 | Pontificia Universidad Catolica de Chile | Phase 4 |
| Unknown | A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer NCT03967327 | Mundipharma (China) Pharmaceutical Co. Ltd | Phase 3 |
| Completed | PCA vs Non-PCA Intravenous Hydromorphone Titration for Severe Cancer Pain NCT03375515 | Fujian Cancer Hospital | Phase 3 |
| Unknown | Individualized Pharmaceutical-care in Outpatients With Cancer Pain NCT03439904 | Zhejiang Cancer Hospital | N/A |
| Unknown | Individualized Pharmaceutical-care for Inpatients With Cancer Pain NCT03455023 | Zhejiang Cancer Hospital | N/A |
| Completed | Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment NCT05558397 | Universidade Federal de Alfenas | N/A |
| Unknown | Adequacy of Pain Treatment in Radiotherapy NCT03550599 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Withdrawn | A Novel mHealth Approach to Assess and Manage Palliative Care Needs for Cancer Patients in Kigali NCT03367637 | Massachusetts General Hospital | N/A |
| Completed | Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in NCT03031938 | Pfizer | Phase 3 |
| Completed | PENS or TENS for Pain in Liver Cancer NCT03338543 | Fuda Cancer Hospital, Guangzhou | N/A |
| Completed | PENS or TENS for Pain in Pancreatic Cancer NCT03331055 | Fuda Cancer Hospital, Guangzhou | N/A |
| Unknown | Endovascular Denervation in Patients With Cancer Pain NCT03431922 | Zhongda Hospital | N/A |
| Completed | Study of Opioid-Induced Constipation 1 Project NCT04350112 | Royal Surrey County Hospital NHS Foundation Trust | — |
| Completed | Study of Opioid-Induced Constipation 2 Project NCT04404933 | Royal Surrey County Hospital NHS Foundation Trust | — |
| Unknown | A Hospital Based Survey on Lung Cancer Related-pain in Northern China NCT03189277 | Chinese Academy of Medical Sciences | — |
| Withdrawn | A Pilot Study to Evaluate the Efficacy of ITDD vs. CMM in the Treatment of Pancreatic Cancer Pain NCT02578459 | Flowonix Medical | N/A |
| Completed | An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared NCT02660229 | Mundipharma Korea Ltd | Phase 4 |
| Completed | Phase 3 Study on the Efficacy and Safety of Tanezumab in Patients With Cancer Pain Due to Bone Metastasis Who NCT02609828 | Pfizer | Phase 3 |
| Unknown | Long-term Effects of Methadone for Cancer Pain NCT02856399 | Hospices Civils de Lyon | — |
| Completed | GREAT - Good Response With Appropriate Treatment NCT02293785 | Mario Negri Institute for Pharmacological Research | — |
| Unknown | Development of a Personalised Care Plan Designed to Reduce Chronic Post-Operative Pain Following Breast Surger NCT02170415 | Royal Marsden NHS Foundation Trust | N/A |
| Completed | Prospective Longitudinal Observational Study to Evaluate the Clinical Characteristics and Opioids Treatments i NCT01946555 | Mario Negri Institute for Pharmacological Research | — |
| Completed | Prometra Post-Approval Study NCT01854229 | Flowonix Medical | N/A |
| Completed | Effect of Early Management on PAin and DEpression in Patients With PancreatoBiliary Cancer, EPADE-PB NCT01589328 | National Cancer Center, Korea | N/A |
| Completed | Study to Evaluate Effectiveness and Tolerability of OROS Hydromorphone for Cancer Pain Treatment in Korean Pat NCT01621100 | Janssen Korea, Ltd., Korea | Phase 4 |
| Completed | RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, NCT01809106 | Mario Negri Institute for Pharmacological Research | Phase 4 |
| Terminated | Study of Breakthrough Cancer Pain: Assessment of Fentanyl Buccal Tablets Titration and Treatment in Opioid-Tol NCT00842829 | Cephalon | Phase 4 |
| Terminated | A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) NCT00803283 | Johnson & Johnson Taiwan Ltd | Phase 3 |
| Completed | An Efficacy and Safety Study of Low-dose Transdermal Therapeutic System (TTS)-Fentanyl D-Trans in Taiwan Parti NCT00771199 | Janssen-Cilag Ltd. | Phase 4 |
| Completed | An Efficacy and Safety Study of Hydromorphone Oral Osmotic System (OROS) in Korean Participants With Cancer Pa NCT00766831 | Janssen Korea, Ltd., Korea | Phase 4 |
| Completed | Gene Transfer for Cancer Pain NCT00804076 | Diamyd Inc | Phase 1 |
| Completed | Case-control Study- Cancer Pain: Uncontrolled Pain as Depression Development Predictor in Oncologic Patients ( NCT01402830 | Janssen-Cilag, S.A. | — |
| Completed | Efficacy & Safety Study of Nasalfent (Fentanyl Citrate Nasal Spray) for Treatment of Breakthrough Cancer Pain NCT00459277 | Archimedes Development Ltd | Phase 3 |
| Completed | Opioid Titration in the Hospice Setting: Barriers Assessment and Modification of the Model Order Sheet and Pro NCT01230515 | Vanderbilt-Ingram Cancer Center | — |