Trials / Recruiting
RecruitingNCT06498037
Optimizing Subcutaneous FEntanyl titRation: RApid Achievement of Adequate Exposure When Treating Cancer-Related paIn.
- Status
- Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 45 (estimated)
- Sponsor
- Erasmus Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 120 Years
- Healthy volunteers
- Not accepted
Summary
The primary objective is to evaluate the effect of loading boluses when dose incresaing treatment with SC fentanyl in patients with cancer. The primary endpoint of this study is to prove the non-inferiority of fentanyl plasma concentrations 12 hours after dose augmentation compared to 48 hours after dose augmentation within each patient. Patients will be treated with additional loading boluses and plasma-PK samples will be obtained.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Fentanyl | Administration of subcutaneously administered fentanyl loading boluses |
Timeline
- Start date
- 2024-02-23
- Primary completion
- 2025-11-01
- Completion
- 2025-12-02
- First posted
- 2024-07-12
- Last updated
- 2024-07-12
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT06498037. Inclusion in this directory is not an endorsement.