| Not Yet Recruiting | Discontinuation of Tobacco Dependence in Smoking Patients With Squamous Cell Carcinoma of the Head-neck Distri NCT06995417 | Azienda Ospedaliero-Universitaria Careggi | — |
| Not Yet Recruiting | Artificial Intelligence-based Voice Assessment of Children and Adults Respiratory Conditions NCT06630078 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Unknown | Lung Ultrasound Score After ENT Cancer Surgery NCT05482841 | Centre Leon Berard | — |
| Completed | Lymphoedema Among Persons With Head- and Neck Cancer NCT05316974 | Lund University | — |
| Withdrawn | Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck NCT05331131 | Northwell Health | Phase 2 |
| Completed | The Gut Microbiome As an Indicator of Readiness for Head & Neck Cancer Surgery NCT05061316 | University of Alabama at Birmingham | N/A |
| Completed | RCT of Effects of Mindfulness-based Stress Reduction in Head and Neck Cancer NCT04800419 | Universiti Sains Malaysia | N/A |
| Active Not Recruiting | A Comprehensive Approach to Head and Neck Cancer Prehabilitation NCT04617678 | Sanford Health | N/A |
| Recruiting | Interest of Bilateral Basic Tongue Mucosectomy Assisted by Robot or Laser in Combination with Tonsillectomy in NCT04767048 | Centre Francois Baclesse | Phase 2 |
| Active Not Recruiting | Onco-primary Care Networking to Support TEAM-based Care NCT04258813 | Duke University | N/A |
| Terminated | Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing NCT04658342 | University of Wisconsin, Madison | — |
| Completed | Trial Evaluating Adapted Chemotherapy in Patients With Squamous Carcinoma NCT04356170 | Groupe Oncologie Radiotherapie Tete et Cou | Phase 2 |
| Completed | Heavy Lifting Strength Training in Head and Neck Cancer Survivors NCT04554667 | University of Alberta | Phase 1 |
| Unknown | Assessment of the Prevalence of Sarcopenia by CT Scan in Patients Diagnosed With Head & Neck Cancer NCT04804852 | Weprom | — |
| Active Not Recruiting | Tempus Priority Study: A Pan-tumor Observational Study NCT05179824 | Tempus AI | — |
| Completed | Postoperative Pain, Why Still in Hospital and DAOH Following TORS for SCCUP & OSAS NCT04189107 | Rigshospitalet, Denmark | Phase 3 |
| Completed | Radiogenomics in Aerodigestive Tract Cancers NCT04314349 | Buddhist Tzu Chi General Hospital | — |
| Completed | Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain NCT03894553 | Jeff Elias, MD | N/A |
| Completed | Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer NCT03993353 | University of California, San Diego | Phase 2 |
| Recruiting | A Multicenter Cancer Biospecimen Collection Study NCT04510129 | Cofactor Genomics, Inc. | — |
| Unknown | Targeting Potassium Channels to Reprogram Glioblastoma Microenvironment: in Vitro and in Vivo Studies NCT03954691 | Neuromed IRCCS | — |
| Completed | Single-arm Phase II Study of NDURE for Patients With HNC NCT03821064 | Medical University of South Carolina | N/A |
| Unknown | The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor NCT03896958 | SpeciCare | — |
| Unknown | Head and Neck Cancer in Children: A Retrospective Study NCT02557048 | Assiut University | — |
| Terminated | Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery NCT03682367 | University of California, Davis | Phase 3 |
| Unknown | Palliative and Oncology Care Intervention: Symptom COACH NCT03760471 | Fox Chase Cancer Center | N/A |
| Unknown | Hypnosis and Meditation for Cancer Pain NCT03558594 | VA Puget Sound Health Care System | N/A |
| Completed | Forecasts Impact of the Pre-therapeutic TEP-TDM in the 18-FDG Restaging of Upper Aero-digestive Tract Cancers NCT03841175 | University Hospital, Brest | — |
| Active Not Recruiting | Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer NCT03383094 | Loren Mell, MD | Phase 2 |
| Completed | Effectiveness and Safety of Nivolumab in Participants That Have Head and Neck Cancer That Has Come Back or Has NCT03569436 | Bristol-Myers Squibb | — |
| Terminated | Study Comparing Pembrolizumab With Methotrexate in Elderly, Frail or Cisplatin-ineligible Patients With Head a NCT03193931 | AIO-Studien-gGmbH | Phase 2 |
| Completed | Prognostic Value of 18FDG PET/CT Textural Indices in HNSCC NCT03378193 | University Hospital, Brest | — |
| Completed | Wearable Sensor for Biometrics During Locoregional Therapy for Head and Neck Cancer NCT03574870 | University of Texas Southwestern Medical Center | N/A |
| Completed | Brain Stimulation For Cancer Smokers NCT03419741 | Medical University of South Carolina | N/A |
| Completed | Nurse-led Exercise Improves Shoulder Pain, Shoulder Disability, and Quality of Life in Head and Neck Cancer NCT05269342 | YU LONG HONG | N/A |
| Completed | Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal NCT02865135 | Dana-Farber Cancer Institute | Phase 1 / Phase 2 |
| Completed | Improving Quality of Life Through the Routine Use of the Patient Concerns Inventory for Head and Neck Cancer P NCT03086629 | Liverpool University Hospitals NHS Foundation Trust | N/A |
| Terminated | Evaluation of an Active Swallowing Rehabilitation on Quality of Life of Patients Treated by Radiotherapy for H NCT02892487 | Rennes University Hospital | N/A |
| Completed | Study to Compare the Effect of Two Different Types of Humidifier on the Endotracheal Tube Patency NCT02780765 | Tata Memorial Hospital | N/A |
| Completed | Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers NCT02648178 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | Swallowing Rehabilitation in Patients With Head and Neck Cancer Receiving Radiotherapy NCT02900911 | Parc de Salut Mar | N/A |
| Completed | Nab-Paclitaxel and Cisplatin or Nab-paclitaxel as Induction Therapy for Locally Advanced Squamous Cell Carcino NCT02573493 | Washington University School of Medicine | Phase 2 |
| Unknown | Big Data and Models for Personalized Head and Neck Cancer Decision Support (BD2Decide) NCT02832102 | Azienda Ospedaliero-Universitaria di Parma | — |
| Completed | Safety and Tolerability Study of AlloVax(TM) in Patients With Metastatic or Recurrent Cancer of the Head and N NCT01998542 | Mirror Biologics, Inc. | Phase 2 |
| Completed | A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) NCT02627274 | Hoffmann-La Roche | Phase 1 |
| Completed | Tertiary Prevention of Head and Neck Cancer With a Dietary Intervention NCT02869399 | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | N/A |
| Completed | Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma NCT02296684 | Washington University School of Medicine | Phase 2 |
| Completed | Multi-Site Pathological Images-Guided ViT for Oral Squamous Cell Carcinoma Recurrence Prediction NCT06638762 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Terminated | Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interaction NCT02402348 | West Virginia University | EARLY_Phase 1 |
| Completed | Pain Control Using Neuromodulation in Patients Undergoing Definitive Chemoradiotherapy for Head and Neck Cance NCT02366611 | University of Michigan | N/A |
| Completed | De-Intensification Radiotherapy Postoperative Head Neck NCT02528955 | University of Erlangen-Nürnberg Medical School | Phase 2 |
| Completed | Quick Diagnostic Program for Head and Neck Cancer NCT02030509 | Corporacion Parc Tauli | — |
| Withdrawn | A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer NCT02013453 | University of Michigan Rogel Cancer Center | Phase 2 |
| Completed | Soy Isoflavone in Combination With Radiation Therapy and Cisplatin in SCC of the Head and Neck NCT02075112 | Emory University | Phase 1 |
| Completed | Hyperbaric Oxygen and Its Effect on Radiation Induced Long Term Side Effects NCT02450305 | State University of New York - Upstate Medical University | — |
| Completed | Comparison of Percutaneous Image-guided Gastrostomies NCT02053428 | University Health Network, Toronto | N/A |
| Completed | Validation of High-resolution PET/CT for the Pretherapeutic Lymphnode Staging of Head/Neck Cancer NCT02372890 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | Efficacy of Novel Edible Gel-based Artificial Saliva in Cancer Patients NCT01885065 | Dental Innovation Foundation Under Royal Patronage | N/A |
| Completed | Exercise and Nutrition for Head and Neck Cancer Patients NCT01681654 | University of Calgary | N/A |
| Completed | Safety Study of Attenuated Vaccinia Virus (GL-ONC1)With Combination Therapy in Head & Neck Cancer NCT01584284 | Genelux Corporation | Phase 1 |
| Unknown | Clinic Study of 18F-Al-NOTA-PRGD2 in Cancer Diagnostics NCT02441972 | Wuxi No. 4 People's Hospital | Phase 1 |
| Completed | Treatment of Pain in Head-and-Neck Cancer Patients: is Methadone More Effective? NCT01317589 | Maastricht University Medical Center | Phase 4 |
| Completed | A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Car NCT01059643 | Eli Lilly and Company | Phase 2 |
| Terminated | To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Partic NCT01284348 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Phase I Chemoprevention Trial With Green Tea Polyphenon E & Erlotinib in Patients With Premalignant Lesions of NCT01116336 | Emory University | Phase 1 |
| Completed | Adaptive Radiation Therapy for Head & Neck Cancer Patients NCT01853670 | Beth Israel Medical Center | N/A |
| Completed | Prognostic Evaluation of 18fmiso Pet-ct in Head and Neck Cancer NCT01235052 | University Hospital, Bordeaux | N/A |
| Completed | Trial of Postoperative Radiation, Cisplatin, and Panitumumab in Locally Advanced Head and Neck Cancer NCT00798655 | Robert Ferris | Phase 2 |
| Completed | Evaluation of Cetuximab (ERBITUX) and Concurrent Carboplatin, Paclitaxel & Radiotherapy in the Management of P NCT00343083 | University of Maryland, Baltimore | Phase 2 |
| Terminated | Assessment of Early Genetic Changes in Smokers NCT00200408 | Montefiore Medical Center | — |
| Completed | The IRESSA Novel Head and Neck Chemotherapy Evaluation Study NCT00255476 | AstraZeneca | Phase 2 |
| Completed | IRESSA in Combination With Cisplatin & Radiotherapy in Patients With Advanced Head & Neck Carcinoma NCT00242749 | AstraZeneca | Phase 2 |
| Completed | Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Hea NCT00318890 | University of Alabama at Birmingham | Phase 1 / Phase 2 |
| Completed | A Phase IB Study Of Oral SCH 66336 Preoperatively In Patients With Head And Neck Squamous Cell Cancer NCT00038584 | M.D. Anderson Cancer Center | Phase 1 |