NCT04658342

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 5 (actual)
• Sponsor: University of Wisconsin, Madison · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate post-operative and post-radiation upper esophageal sphincter opening measures in oral cancer patients, compare measures to age- and gender-matched healthy adults, and determine relationships with patient swallowing outcomes and quality of life.

Conditions

• Cancer of Head and Neck

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Videofluoroscopic imaging (VFSS) with high-resolution manometry (HRM)	The Videofluoroscopic Imaging (VFSS) is done by inserting a small catheter into the nose and down the throat. The catheter is approximately .4 millimeters in diameter. A trained speech-language pathologist will insert the catheter after applying numbing medicine, or topical anesthetic, inside the nose. The high-resolution manometry (HRM) is a swallowing pressure test done at the same time as the VFSS. The HRM will measure how strong the throat muscle squeeze the liquids and foods that a person swallows. The VFSS and HRM will occur about one month after surgery and three months after the completion of the radiation treatment.

Timeline

• Start date: 2021-04-16
• Primary completion: 2023-03-25
• Completion: 2023-03-25
• First posted: 2020-12-08
• Last updated: 2024-12-18

Locations

1 site across 1 country: United States