| Not Yet Recruiting | VIATORR® TIPS Study Evaluating 6-10mm Diameters (VIATIPS) NCT07390344 | W.L.Gore & Associates | — |
| Recruiting | Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis NCT07521332 | Asian Institute Of Medical Sciences | Phase 4 |
| Recruiting | Intraperitoneal SK-NK Cell Injection for Advanced Ovarian Cancer With Massive Ascites NCT07435701 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Phase 1 / Phase 2 |
| Recruiting | Free Fluid Detection With Telementored eFAST NCT06594562 | Oslo University Hospital | N/A |
| Recruiting | Kinesio-Taping vs. Usual Care for Malignant Bowel Obstruction With Ascites NCT07023042 | National Taiwan University Hospital | N/A |
| Recruiting | Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast Cancer NCT06658080 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Not Yet Recruiting | High Definition Profiling of Ovarian Cancer Ascites NCT06553742 | European Institute of Oncology | — |
| Recruiting | Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in China NCT07113808 | The Children's Hospital of Zhejiang University School of Medicine | — |
| Completed | PMCF Study of the CE-marked Drainova® ArgentiC Catheter NCT06436807 | ewimed GmbH | — |
| Enrolling By Invitation | Application of Bacterial DNA Quantitative Detection in Diagnosis of SBP in Cirrhosis: A Multi Center Diagnosti NCT06995846 | Beijing YouAn Hospital | — |
| Unknown | The INSIGHT Feasibility Study Ultrasound in the Intensive Care Unit: A Randomised Controlled Feasibility Trial NCT05569798 | King's College Hospital NHS Trust | N/A |
| Terminated | Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites ( NCT05900050 | Genfit | Phase 2 |
| Completed | Lung Point of Care Ultrasound to Guide Albumin Administration in Cirrhosis NCT07072572 | Centro Medico Issemym | Phase 3 |
| Unknown | Clinical Validation of Programmable Drain Fluid Regulator to Reduce Morbidity, Care Requirements, and Improve NCT05734729 | Changi General Hospital | N/A |
| Unknown | Comparison of Crystalloid and Colloid I.V Fluid Therapy in Prevention of Paracentesis Induced Circulatory Dysf NCT05220891 | Shady Ashraf Kassem | — |
| Unknown | Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in C NCT05700708 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Unknown | Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis NCT05511766 | Tanta University | Phase 2 / Phase 3 |
| Completed | A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney NCT05309200 | Ocelot Bio, Inc | Phase 2 |
| Unknown | Utility of 2- Octyl Cyanoacrylate (2-OCA) NCT05278013 | Methodist Health System | N/A |
| Completed | Empagliflozin in Diuretic Refractory Ascites NCT05013502 | Stanford University | Phase 1 |
| Recruiting | 13C-Glucose Tracing of Tumour and T Cells in the Ascites of Ovarian Cancer Patients. NCT05025878 | British Columbia Cancer Agency | — |
| Terminated | A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory NCT04112199 | BioVie Inc. | Phase 2 |
| Completed | Investigating Signal Change in Malignant and Non-malignant Pleural Effusions and asCitic Fluid Using fTiR Anal NCT04533854 | Portsmouth Hospitals NHS Trust | — |
| Completed | Comparative Study of Secondary Prophylaxis for SBP NCT06827756 | Tanta University | Phase 4 |
| Unknown | TIPS Combined With Microwave Ablation in HCC Patients With Refractory Ascites NCT04640116 | Sun Yat-sen University | N/A |
| Completed | The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy. NCT04675775 | University of Michigan | N/A |
| Completed | Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles Trial NCT04650295 | University of Michigan | N/A |
| Unknown | Role Of Multi-detector Computed Tomography In Differentiation Between Different Types Of Ascites NCT04550091 | Assiut University | — |
| Terminated | Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal Carcinomatosi NCT04232384 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Unknown | Cell Block Immunohistochemistry in Effusion Cytology NCT04279327 | Assiut University | — |
| Active Not Recruiting | Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Co NCT04315571 | University of California, Los Angeles | N/A |
| Completed | Phase Ib of Recombinant Human Albumin Injection NCT04701697 | The First Hospital of Jilin University | Phase 1 |
| Completed | Does Point of Care Ultrasound Change Needle Insertion Location During Routine Bedside Paracentesis? NCT04245553 | Steven Montague | N/A |
| Unknown | Alfapump® System in the Treatment of Refractory or Recurrent Ascites (POSEIDON Study) NCT03973866 | Sequana Medical N.V. | N/A |
| Completed | Safety and Tolerance Study of Recombinant Human Albumin Injection in Healthy Subjects. NCT04641364 | The First Hospital of Jilin University | Phase 1 |
| Terminated | A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis NCT03827200 | Noorik Biopharmaceuticals AG | Phase 2 |
| Recruiting | High Dose Albumin in Refractory Ascites NCT05867602 | Baylor College of Medicine | Phase 2 |
| Recruiting | Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic NCT03506893 | University Hospital, Grenoble | N/A |
| Completed | Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With A NCT03069131 | Centre Hospitalier Universitaire de Besancon | Phase 3 |
| Completed | Tackling 30-day Readmissions in Patients With Cirrhosis: The SALTYFOOD Trial NCT03493204 | University of Michigan | N/A |
| Suspended | Preoperative Ascites Drainage Versus Standard Care for Patients With Advanced Ovarian Cancer NCT02742428 | Gdynia Oncology Center | N/A |
| Unknown | Diagnosis of Ascites in Infants and Children NCT03341221 | Assiut University | — |
| Completed | Point-of-care Ultrasound in Finland NCT03327688 | Ossi Hannula | N/A |
| Unknown | Evaluation of Different Etiologies of Obscure Ascites NCT03205748 | Assiut University | — |
| Recruiting | VICIS - Vienna Cirrhosis Study NCT03267615 | Medical University of Vienna | — |
| Completed | Peritoneal Dialysis Catheters for the Treatment of Refractory Ascites NCT02975726 | University of Manitoba | N/A |
| Unknown | Liquid Biopsy With Immunomagnetic Beads Capture Technique for Malignant Cell Detection in Body Fluid NCT02891642 | The First Affiliated Hospital with Nanjing Medical University | — |
| Withdrawn | Bedside Inoculation of Ascitic Fluid in Diagnostic Paracentesis NCT02895919 | Medical College of Wisconsin | — |
| Unknown | The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With A NCT02755701 | Soonchunhyang University Hospital | Phase 4 |
| Unknown | The Role of Intravenous Albumin Replacement During Abdominal Paracentesis in Patients With Malignancy Related NCT02811406 | National University Hospital, Singapore | N/A |
| Completed | Validation of Diagnostic Usefulness of the Random Urine Na/K Ratio for Replacement of 24hr Urine Na Excretion NCT03263598 | Jang Byoung Kuk | — |
| Completed | Evaluation of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With Decompensated Cirrhosis Wit NCT02608658 | St. Louis University | N/A |
| Unknown | International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) NCT03210298 | Sabine Rhode | — |
| Completed | To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites NCT02649335 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 3 |
| Terminated | AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites NCT02417753 | National Cancer Institute (NCI) | Phase 2 |
| Completed | A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effecti NCT02400164 | Sequana Medical N.V. | N/A |
| Recruiting | Cirrhosis Registry of Hospitalized Patients NCT04767945 | F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica | — |
| Completed | Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT NCT02638051 | Galenic Research Institute Ltd | Phase 2 |
| Unknown | Comparative Study of Rifaximin Versus Norfloxacin in the Secondary Prophylaxis of Spontaneous Bacterial Perito NCT02120196 | Sherief Abd-Elsalam | Phase 3 |
| Completed | Metabolic Effects of Furosemide +HSS in Refractory Ascites NCT02821377 | University of Palermo | Phase 2 |
| Withdrawn | Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis; a Study of Efficacy and Side NCT01801228 | Emma Nilsson | Phase 2 |
| Unknown | Body Composition Analysis in Cirrhotic Undergoing Paracentesis NCT02022150 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | — |
| Completed | Intestinal Decontamination With Rifaximin. The Inflammatory and Circulatory State in Patients With Cirrhosis NCT01769040 | Copenhagen University Hospital, Hvidovre | Phase 4 |
| Unknown | Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites NCT01716611 | Konkuk University Medical Center | Phase 4 |
| Withdrawn | The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis NCT01777971 | NYU Langone Health | — |
| Completed | Tolvaptan for Ascites in Cirrhotic Patients NCT01292304 | University of Florida | Phase 4 |
| Terminated | VSL#3 and Spontaneous Bacterial Peritonitis NCT01701297 | Nottingham University Hospitals NHS Trust | Phase 2 |
| Withdrawn | Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis NCT01331785 | The Cleveland Clinic | N/A |
| Completed | Human Albumin for the Treatment of Ascites in Patients With Hepatic Cirrhosis NCT01288794 | University of Bologna | Phase 4 |
| Completed | Improving Performance of Paracentesis in Medical Residency Training NCT01403987 | Boston Medical Center | N/A |
| Unknown | Conservative Treatment Versus Elective Repair of Umbilical Hernia in Patients With Ascites and Liver Cirrhosis NCT01421550 | Erasmus Medical Center | Phase 3 |
| Terminated | Early TIPS for Ascites Study NCT01236339 | W.L.Gore & Associates | N/A |
| Terminated | Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis NCT01455246 | University of Padova | Phase 2 / Phase 3 |
| Completed | Phase III Study of Tolvaptan Tablet to Treat Cirrhosis Ascites NCT01349348 | Otsuka Beijing Research Institute | Phase 3 |
| Completed | Impact of Palliative Catheter Placement on the Quality of Life of Patients With Refractory Ascites NCT01188746 | Memorial Sloan Kettering Cancer Center | N/A |
| Completed | B-type Natriuretic Peptide in the Diagnosis of Heart Failure Related Ascites NCT01150916 | University of Sao Paulo | N/A |
| Withdrawn | The Influence of Paracentesis on Intra-abdominal Pressure and Kidney Function in Critically Ill Patients With NCT01091233 | University Hospital, Ghent | — |
| Unknown | Portal Venous Hemodynamic Changes After Hepatectomy NCT01073345 | Heidelberg University | — |
| Completed | Safety and Performance of the Automated Fluid Shunt in Patients With Ascites and Diuretic Resistance NCT01030185 | NovaShunt AG | Phase 2 / Phase 3 |
| Completed | Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal NCT01059396 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 4 |
| Completed | Procalcitonin in Cirrhotic Patients at High Risk for Sepsis NCT01578226 | Prof. Facchinetti Fabio | — |
| Completed | Effects of Long Term Albumin 20% Administration in Patients With Cirrhosis and Ascites. NCT00968695 | Instituto Grifols, S.A. | Phase 4 |
| Completed | The Automated Fluid Shunt (AFS)in Chronic Congestive Heart Failure NCT00907673 | NovaShunt AG | N/A |
| Completed | Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascites NCT01349335 | Otsuka Beijing Research Institute | Phase 2 |
| Completed | Multiple-dose Pharmacokinetics Study of Tolvaptan Tablets in Chinese Patients With Hepatocirrhosis NCT01359462 | Otsuka Beijing Research Institute | Phase 1 |
| Completed | Long-term Follow-up of HALT-C Sustained Virological Responders NCT00825877 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Abdominal Hernia in Cirrhotic Patients: Surgery or Conservative Treatment? NCT02787772 | University of Sao Paulo General Hospital | N/A |
| Withdrawn | Effect of Large Volume Paracentesis on Fatigue in Cirrhosis NCT00603200 | Weill Medical College of Cornell University | — |
| Completed | Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community NCT00591968 | Edward Via Virginia College of Osteopathic Medicine | N/A |
| Terminated | Sodium Restriction in the Management of Cirrhotic Ascites NCT00548366 | University of Texas Southwestern Medical Center | Phase 4 |
| Suspended | Acute Hemodynamics of Albumin Versus Normal Saline in Cirrhosis NCT00511394 | Govind Ballabh Pant Hospital | N/A |
| Terminated | Trial of Sunitinib for Refractory Malignant Ascites NCT00796861 | Milton S. Hershey Medical Center | Phase 2 |
| Terminated | Satavaptan for the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver NCT00366795 | Sanofi | Phase 3 |
| Completed | Study of the Effect of Intravenous AVE0005 (VEGF Trap) in Advanced Ovarian Cancer Patients With Recurrent Symp NCT00327444 | Sanofi | Phase 2 / Phase 3 |
| Terminated | Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver NCT00359437 | Sanofi | Phase 3 |
| Completed | Cirrhotic Ascites Treatment With Satavaptan in Patients With Ascites Due to Cirrhosis of the Liver (CATS) NCT00358878 | Sanofi | Phase 3 |
| Unknown | Prevention of Decompensation in Liver Cirrhosis NCT00239096 | Odense University Hospital | Phase 4 |
| Completed | Spironolactone Versus Spironolactone Plus Furosemide (SVSSF) NCT00741663 | University of Padova | Phase 4 |
| Completed | Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosis NCT00570622 | Medical University of Vienna | Phase 4 |
| Completed | Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites NCT00115947 | Hvidovre University Hospital | Phase 2 / Phase 3 |
| Completed | Satavaptan Dose-Ranging Study in the Prevention of Ascites NCT00501384 | Sanofi | Phase 2 |
| Completed | Satavaptan Dose-Ranging Study in Normonatraemic Patients With Cirrhotic Ascites NCT00501566 | Sanofi | Phase 2 |
| Completed | Satavaptan Dose-Ranging Study in Hyponatraemic Patients With Cirrhotic Ascites NCT00501722 | Sanofi | Phase 2 |
| Completed | Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis NCT00108355 | US Department of Veterans Affairs | Phase 4 |
| Completed | Treatment With Octreotide in Patients With Lymphangioleiomyomatosis NCT00005906 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | North American Study for the Treatment of Refractory Ascites (NASTRA) NCT00006166 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 3 |
| Completed | Spontaneous Bacterial Peritonitis: Incidence, Risk Factors and Outcome NCT00490217 | Tampere University | — |
| Withdrawn | Lipopolysaccharide Binding Protein and Development of Infectious Events in Cirrhotic Patients NCT00760032 | Florencia Vargas-Vorackova | Phase 4 |