Trials / Completed
CompletedNCT01059396
Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal
Multicenter, Randomized, Double-blind, Placebo-controlled Study on the Effectiveness of Treatment With Beta-blockers to Prevent Decompensation of Cirrhosis With Portal Hypertension
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 201 (actual)
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This is a multicenter, randomized, double-blind, placebo-controlled study on the effectiveness of treatment with beta-blockers to prevent decompensation of cirrhosis with portal hypertension.
Conditions
- Portal Hypertension Gastropathy
- Esophageal Varices
- Spontaneous Bacterial Peritonitis
- Hepatic Encephalopathy
- Ascites
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | propranolol | GPVH ≥ 10 mmHg - responders: propranolol. |
| DRUG | carvedilol | GPVH ≥ 10 mmHg nonresponders: carvedilol. |
| DRUG | placebo | placebo propranolol / carvedilol |
Timeline
- Start date
- 2010-01-28
- Primary completion
- 2015-07-15
- Completion
- 2015-07-15
- First posted
- 2010-01-29
- Last updated
- 2017-08-22
Locations
8 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT01059396. Inclusion in this directory is not an endorsement.