| Not Yet Recruiting | False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study (FLAGS NCT06740721 | Shape Memory Medical, Inc. | N/A |
| Not Yet Recruiting | LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients NCT07521488 | Beijing Anzhen Hospital | N/A |
| Not Yet Recruiting | False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study (FLAGS NCT07387250 | Shape Memory Medical, Inc. | N/A |
| Not Yet Recruiting | Nutritional Ketosis Marfan NCT07495267 | Washington University School of Medicine | N/A |
| Recruiting | False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study NCT06550986 | Shape Memory Medical, Inc. | N/A |
| Not Yet Recruiting | CLEAR Trial: CA330 Cytokine Adsorption Column for Anticoagulant/Antiplatelet Patients in Non-Elective CPB Surg NCT07284199 | Beijing Anzhen Hospital | N/A |
| Recruiting | Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection NCT06968806 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Phase 3 |
| Not Yet Recruiting | Guo&Amp;'s Distal Entry Tear Repair With WeFlow-EndoPatch System (Gallant Study) NCT06945809 | Hangzhou Endonom Medtech Co., Ltd. | N/A |
| Recruiting | GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections NCT06827990 | W.L.Gore & Associates | N/A |
| Enrolling By Invitation | Research on the Development and Implementation of an Exercise Rehabilitation Program for Aortic Dissection Pat NCT07117500 | Shuzhen Wang | N/A |
| Recruiting | Study on the Aortic Arch Single Branch Stent Graft System NCT06915545 | Lifetech Scientific (Shenzhen) Co., Ltd. | N/A |
| Enrolling By Invitation | Protective Effect of Ulinastatin and Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction A NCT06966687 | Nanjing Medical University | N/A |
| Not Yet Recruiting | POCUS Screening for TAA in Hypertensive Patients in the ED NCT06854588 | Chinese University of Hong Kong | — |
| Active Not Recruiting | Aortic Dissection fAlse enlarGement radIomics predictiOn NCT07117825 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Not Yet Recruiting | Optimized Strategies for Malperfusion Syndrome NCT06532838 | Xiamen Cardiovascular Hospital, Xiamen University | N/A |
| Recruiting | Hemiarch vs Extended Arch in Type 1 Aortic Dissection NCT03885635 | Ottawa Heart Institute Research Corporation | N/A |
| Recruiting | Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular NCT06195267 | Nanjing Medical University | N/A |
| Enrolling By Invitation | SPIRIT: Study of the Patency of Spinal aRteries After the STABILISE Technique NCT06373393 | Associacao para Investigacao e Desenvolvimento da Faculdade de Medicina - CETERA | — |
| Not Yet Recruiting | REgistRy BRAnch goRE EndopRosthEsis NCT06276413 | University Hospital Padova | — |
| Enrolling By Invitation | Optimal Strategy for Repair of Type A Acute Aortic Dissection NCT05912608 | Centre Cardiologique du Nord | N/A |
| Active Not Recruiting | Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes NCT05389865 | Golden Jubilee National Hospital | — |
| Unknown | Safety and Efficacy of the Minimally Invasive Bentall Procedure Via a Small Right Intercostal Incision in Pati NCT06177548 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Enrolling By Invitation | Evaluation of the GORE® Ascending Stent Graft NCT05800743 | W.L.Gore & Associates | N/A |
| Recruiting | Clinical Characteristics and Prognosis of Aortic Dissection in China (CLASSIC) NCT05999188 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Recruiting | Study Comparing Hemiarch Replacement and Hemiarch Plus Stent Implantation in Acute Aortic Dissection NCT06044259 | Chinese University of Hong Kong | N/A |
| Completed | Prospective Feasibility Study of Point-of-care Ultrasound in Suspected Aortic Dissection NCT05897476 | Centre Hospitalier Universitaire de Besancon | N/A |
| Unknown | A Real World Study on Fabulous® Thoracic Aortic Stent System for Stanford B Aortic Dissection NCT05965271 | Hangzhou Endonom Medtech Co., Ltd. | — |
| Active Not Recruiting | Cerebral Protection in Aortic Arch Surgery NCT04966247 | Barts & The London NHS Trust | — |
| Recruiting | Potential Diagnostic Biomarkers for Aortic Dissection in the Emergency Department NCT06065306 | Chinese University of Hong Kong | — |
| Recruiting | Scandinavian Trial of Uncomplicated Aortic Dissection Therapy NCT05215587 | University of Aarhus | N/A |
| Unknown | A Real-World Study on Distal Aortic Remodeling for Stanford Type B Aortic Dissection With Fabulous Thoracic Ao NCT05883592 | Hangzhou Endonom Medtech Co., Ltd. | — |
| Active Not Recruiting | Thoraflex Hybrid and Relay Extension Post-Approval Study NCT05639400 | Vascutek Ltd. | — |
| Active Not Recruiting | The Branch-based Intraoperative Stent System in the Treatment of Stanford A Aortic Dissection（BROAD） NCT05659641 | Permed Biomedical Engineering Co., Ltd | N/A |
| Unknown | LANDMARC Study: a Study With Focus on Aorta Ascendens NCT05655767 | Maastricht University Medical Center | — |
| Recruiting | Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics NCT06001073 | First Affiliated Hospital Xi'an Jiaotong University | — |
| Unknown | Quick Recognition of Aortic Dissection NCT05699395 | Shanghai Zhongshan Hospital | — |
| Completed | The DAShED (Diagnosis of Aortic Syndrome in the ED) Study NCT05582967 | NHS Lothian | — |
| Unknown | Safety and Efficacy Study Of The Thoracic Aortic Stent Graft System Treating Aortic Dissection NCT05430672 | Zhejiang Zylox Medical Device Co., Ltd. | N/A |
| Unknown | Clinical Investigation of Clinical Safety and Performance of the SP-GRIPFLOW, Selective Cerebral Perfusion Cat NCT05421130 | Fuji Systems Corporation | N/A |
| Unknown | Population Pharmacokinetics of Lassila Tazobactam in Patients After Aortic Dissection NCT05349305 | The Second Hospital of Shandong University | — |
| Completed | Correlation Study of PAI-1 4G/5G Polymorphism and Postoperative AKI in Patients With Aortic Dissection NCT05490394 | Xijing Hospital | — |
| Unknown | Improvement of Pulmonary Insufficiency After Aortic Dissection With Sivelestat Sodium NCT05343338 | First Affiliated Hospital Xi'an Jiaotong University | N/A |
| Unknown | Effects of Intraoperative Hemoperfusion on Acute Kidney Injury After Aortic Dissection NCT05331495 | First Affiliated Hospital Xi'an Jiaotong University | N/A |
| Unknown | Shear Stress Endothelial/Hemodynamics in Aortic Dissection and Endothelial Shear Stress-biological Profile NCT05745428 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Unknown | Concave Supra-arch Branched Stent-Graft System for Treatment of Aortic Arch Diseases NCT05996354 | China National Center for Cardiovascular Diseases | N/A |
| Completed | Intravascular Ultrasound for the Evaluation of Malperfusion Syndrome in the Setting of Acute Aortic Dissection NCT04907071 | London Health Sciences Centre | N/A |
| Completed | Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial) NCT05329740 | Shanghai Zhongshan Hospital | Phase 4 |
| Unknown | Endovascular Repair With In Situ nEedle feNestration of Left Subclavian Artery to Treat AoRtic Dissection(RISE NCT05186181 | First Affiliated Hospital of Zhejiang University | — |
| Completed | Clinical Features, Outcomes, and Therapeutics of Pregnancy-Related Aortic Dissection NCT05501145 | Nanjing Medical University | — |
| Terminated | Antibiotic Prophylaxis for TEVAR NCT05405790 | First Affiliated Hospital of Zhejiang University | — |
| Unknown | Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR. NCT05073991 | Mahidol University | — |
| Withdrawn | The Effects of Exercise on Quality of Life and Fluid Dynamics in Patients With Aortic Dissection NCT05499650 | University of Maryland, Baltimore | N/A |
| Completed | Angiotensin II Pathway and Postoperative Hypoxemia NCT05055570 | Beijing Anzhen Hospital | — |
| Active Not Recruiting | PMCF Study in Patients With Acute or Chronic Aortic Dissection or Aortic Aneurysm Treated With E-vita OPEN NEO NCT04986709 | JOTEC GmbH | — |
| Unknown | 4D Motion of the Aorta in the Chest and Simulated Wall Stress Distribution in Relation to Aortic Events NCT04958083 | Royal Brompton & Harefield NHS Foundation Trust | N/A |
| Active Not Recruiting | the Aorta Arch Stent Graft System Combined With the Endovascular Needle System in Situ Fenestration NCT05126446 | Lifetech Scientific (Shenzhen) Co., Ltd. | N/A |
| Recruiting | Valved Graft PMCF Study NCT04754217 | Abbott Medical Devices | — |
| Completed | The Effect of the CytoSorb® Filter to Remove Anticoagulants From the Circulation During Emergency Surgery for NCT05235178 | Oslo University Hospital | — |
| Recruiting | B-SAFER: Branched Stented Anastomosis Frozen Elephant Trunk Repair NCT04747626 | Eric Roselli, M. D. | N/A |
| Recruiting | Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular Gr NCT04746677 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Biomarkers in Thoracic Aorta Surgery NCT04689139 | Petrovsky National Research Centre of Surgery | N/A |
| Unknown | Prospective Study of Tailored Management Strategies for Malperfusion Syndrome NCT05517356 | Xiamen Cardiovascular Hospital, Xiamen University | N/A |
| Unknown | Additive Anti-inflammatory Action for Critically Ill Patients With Cardiovascular Surgery (Xuebijing) IV NCT04993794 | Nanjing Medical University | N/A |
| Completed | Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Multicenter Cohort Study) III NCT04918108 | Nanjing Medical University | — |
| Completed | Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection NCT07167628 | China Medical University Hospital | — |
| Active Not Recruiting | A PMCF Study in Patients With Acute or Chronic Aortic Dissection or Aortic Aneurysm Treated With E-vita OPEN N NCT04676672 | JOTEC GmbH | — |
| Recruiting | NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness NCT04471909 | Endospan Ltd. | N/A |
| Completed | Prediction of Postoperative Acute Kidney Injury in Patients With Acute Type A Aortic Dissection Using Cystatin NCT05039814 | Qilu Hospital of Shandong University | — |
| Unknown | Study on Susceptibility Genes and Pathogenic Mechanism of Non-syndromic Familial Aortic Dissection NCT04439565 | Chinese Medical Association | — |
| Unknown | Diagnostic Value of D-dimer/Fibrinogen Ratio in Patients With Acute Aortic Dissection NCT04251247 | Dr. Lutfi Kirdar Kartal Training and Research Hospital | — |
| Unknown | Pre-hospital Management of Aortic Dissection NCT04304443 | Centre Hospitalier Universitaire de Besancon | — |
| Unknown | Functional Study of Metabolites in Patients With Aortic Dissection NCT04450433 | Shenzhen People's Hospital | — |
| Terminated | Digital Home Blood Pressure Monitoring in Type B Aortic Dissection Patients NCT04116684 | The Cleveland Clinic | N/A |
| Unknown | Magnetic Resonance Imaging (MRI) for Aortic Dissection to Visualise Inflammation NCT03948555 | University of Leicester | — |
| Recruiting | Nordic Consortium for Acute Type a Aortic Dissection-2 NCT06862583 | Karolinska Institutet | — |
| Unknown | Biomechanical Reappraisal of Planning for Thoracic Endovascular Aortic Repair NCT03824626 | Ospedale San Donato | — |
| Completed | Assessment of Risk in Thoracic Aortopathy Using 18F-Sodium Fluoride NCT04083118 | University of Edinburgh | — |
| Active Not Recruiting | Post-market Registry of the AMDS for the Treatment of Acute DeBakey Type I Dissection NCT03894033 | JOTEC GmbH | — |
| Completed | Hemodynamic Changes in the Aorta After Endovascular Treatment of the Aortic Dissection NCT03669055 | Hospices Civils de Lyon | N/A |
| Active Not Recruiting | Registry of Patients With Acute/Subacute Type B Aortic Dissection Treated by Means of the STABILISE Technique NCT03707743 | IRCCS San Raffaele | — |
| Enrolling By Invitation | Endovascular Treatment of Thoracic Aortic Disease NCT00583817 | Matthew Eagleton | N/A |
| Unknown | A Validation Study of The Relationship Between ALDH2 and Aortic Dissection NCT03780738 | Qilu Hospital of Shandong University | — |
| Completed | 18F Sodium Fluoride PET/CT in Acute Aortic Syndrome NCT03647566 | University of Edinburgh | — |
| Completed | Freestyle Prosthesis for Aortic Root-replacement With and Without Hemiarch Replacement NCT04068337 | Triemli Hospital | — |
| Active Not Recruiting | Thoraflex Hybrid Post-Market Study NCT03414866 | Vascutek Ltd. | — |
| Unknown | On-table Renal Perfusion Evaluation Renal Artery Stenosis or Obstruction NCT03530748 | Shanghai Zhongshan Hospital | — |
| Recruiting | Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients NCT04937868 | University of California, Los Angeles | — |
| Completed | Factors Influencing Perioperative Mortality in Type A Acute Aortic Dissections Operated at Dijon University Ho NCT04408404 | Centre Hospitalier La Chartreuse | — |
| Unknown | Clinical Study for Evaluating the Safety and Efficacy of Total Endovascular Aortic Arch Repair NCT03347812 | Chinese Academy of Medical Sciences, Fuwai Hospital | — |
| Completed | DARTS I Feasibility Study NCT03035643 | Ascyrus Medical LLC. | N/A |
| Completed | The Roles of Intraluminal Pressure and the Dilation of Tunica Media in the Development of Aortic Dissection NCT03030521 | Wuhan Asia Heart Hospital | — |
| Completed | Percutaneous Plug-based Femoral Arteriotomy Closure Device Use in Surgery for Acute Type A Aortic Disection NCT05482555 | Karolinska University Hospital | — |
| Completed | Different Antihypertensive Drugs on Aortic Diseases NCT06626607 | Eighth Affiliated Hospital, Sun Yat-sen University | — |
| Terminated | My Research Legacy Pilot Study NCT02958098 | American Heart Association | — |
| Completed | Thoraflex™ Hybrid IDE Study NCT02724072 | Bolton Medical | N/A |
| Recruiting | Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease NCT04005976 | The University of Texas Health Science Center, Houston | — |
| Unknown | Significance of Serum Tenascin C in Patients With Acute Aortic Disease NCT02816892 | Central South University | — |
| Unknown | Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years NCT02837120 | Qilu Hospital of Shandong University | — |
| Unknown | Cerebral and Spinal Protection of Xenon Post-conditioning in Patients Undergoing Aortic Dissection Repair NCT02774096 | Beijing Anzhen Hospital | N/A |
| Unknown | The Relationship Between ALDH2 and Aortic Dissection NCT02630212 | Qilu Hospital of Shandong University | — |
| Unknown | Glucocorticoid on the Prognosis of TEVAR NCT02523300 | Changhai Hospital | N/A |
| Active Not Recruiting | ARISE: Evaluation of the GORE® Ascending Stent Graft in the Treatment of DeBakey Type I/II Aortic Dissection NCT02380716 | W.L.Gore & Associates | — |
| Completed | Zenith® TXD Post-market Surveillance in Japan NCT02663739 | Cook Group Incorporated | — |
| Unknown | A Single-center Trial of Patients With Aortic Dissection in the Chinese XinJiang Province NCT02378103 | Xiang Ma | — |
| Completed | Characterization of Aortic Tissue at Reoperation NCT02375542 | CryoLife Europa | — |
| Completed | Outcomes of Secondary Endovascular Aortic Repair After Initial Frozen Elephant Trunk Procedure NCT05571930 | University Paul Sabatier of Toulouse | — |
| Completed | Aortic Dissection Detection Risk Score Plus D-dimer in Suspected Acute Aortic Dissection NCT02086136 | Azienda Ospedaliero-Universitaria Careggi | — |
| Recruiting | Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified E NCT02043691 | University of Alabama at Birmingham | N/A |
| Recruiting | Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study NCT03233087 | Beijing Institute of Heart, Lung and Blood Vessel Diseases | — |
| Enrolling By Invitation | Repair Versus Non-repair of the Aortic Arch in Type A Aortic Dissection NCT05912634 | Centre Cardiologique du Nord | — |
| Recruiting | Feasibility of Endovascular Repair Of Ascending Aortic Pathologies NCT02201589 | Rodney A. White, MD | N/A |
| Recruiting | Cardiovascular Health Improvement Project NCT02306200 | University of Michigan | — |
| Unknown | Potential Biomarkers for Early Diagnosis of Acute Aortic Dissection NCT01860768 | Central South University | — |
| Completed | Zenith® Dissection Clinical Trial NCT01568320 | Cook Research Incorporated | N/A |
| Completed | Point-of-Care Focused Cardiac Ultrasound in Assessing the Thoracic Aorta NCT01671618 | Yale University | — |
| Completed | CoSeal for Hemostasis of Aortic Anastamoses NCT01653769 | Michael Reardon, MD | — |
| Completed | Clinical Characteristics, Management Patterns and Outcomes of Type A Aortic Dissection: A Sino-US Comparative NCT05409469 | Xin Chen | — |
| Unknown | Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection NCT01552720 | Xijing Hospital | — |
| Terminated | Long-term Benefit of Aortic Stent-graft in Patients With Distal Aortic Dissection NCT01354119 | Asan Medical Center | Phase 4 |
| Completed | Study to Evaluate the Clinical Performance of the Valiant Thoracic Stent Graft With the Captivia Delivery Syst NCT01114724 | Medtronic Cardiovascular | N/A |
| Completed | Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation NCT01206751 | Taipei Medical University WanFang Hospital | — |
| Completed | Aortic-Stent-Register NCT01197651 | Stiftung Institut fuer Herzinfarktforschung | — |
| Completed | Zenith® Dissection Endovascular System NCT02094300 | Cook Group Incorporated | N/A |
| Completed | The VIRTUE Post Marketing Surveillance Registry NCT01213589 | Medtronic Endovascular | — |
| Completed | Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain NCT00855231 | University of Washington | — |
| Completed | Surgery for Delay-recognized or Defer-operated Type A Aortic Dissection NCT05044494 | Mackay Memorial Hospital | — |
| Completed | Logistic Regression of Risk Factor for the 5-year Mortality of Aortic Dissection NCT01782534 | Central South University | — |
| Completed | Investigation of Stent-grafts in Aortic Dissection (INSTEAD) NCT01415804 | University of Rostock | Phase 2 / Phase 3 |
| Approved For Marketing | Zenith® Dissection Endovascular System in the Treatment of Patients With Aortic Dissections NCT02464943 | Cook Research Incorporated | — |