| Not Yet Recruiting | LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients NCT07521488 | Beijing Anzhen Hospital | N/A |
| Recruiting | AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation NCT07438327 | Aiatella Oy | — |
| Not Yet Recruiting | Bentley Bridging Stent Graft Study NCT07295145 | Bentley InnoMed GmbH | — |
| Recruiting | A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an O NCT07078383 | Vascutek Ltd. | N/A |
| Recruiting | Prehabilitation for Aortic Aneurysm Surgery: Proof-of-concept Trial NCT06998498 | Massachusetts General Hospital | N/A |
| Active Not Recruiting | ANATOMICAL FEASIBILITY OF BRAILE STANDARD BRANCHED ENDOGRAFT NCT07118995 | Braile Biomedica Ind. Com. e Repr. Ltda. | — |
| Recruiting | Radiation Free Study NCT06549348 | Philips Clinical & Medical Affairs Global | N/A |
| Not Yet Recruiting | Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery NCT06918496 | Grena Biomed Limited | N/A |
| Recruiting | Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Complex Aortic A NCT06834607 | Akhilesh Jain | N/A |
| Recruiting | Prophylactic Mesh Reinforcement After Open Aortic Aneurysm Repair NCT06762561 | Hôpital Fribourgeois | — |
| Not Yet Recruiting | AI-enhanced Imaging Analysis to Predict Post-EVAR NCT06592105 | Centre Hospitalier Universitaire de Nice | — |
| Recruiting | Safety and Effectiveness of Physician-Modified Fenestrated and Branched Aortic Endografting for the Treatment NCT06501872 | Bjoern D. Suckow | N/A |
| Recruiting | Laser In Situ Fenestration Study NCT06411990 | Jonathan Bath | N/A |
| Recruiting | Improved Recovery by Iron Following Surgery With Blood Loss, the IRIS-trial NCT05744219 | Jon Unosson | Phase 3 |
| Recruiting | Gastrointestinal Dysfunction in Aortic Surgery Patients NCT06514170 | Instituto Nacional de Cardiologia Ignacio Chavez | — |
| Recruiting | Semibranch Registry - Retrospective NCT06374355 | University Hospital Muenster | — |
| Recruiting | Utilizing 3D Printed Personalized Aortic Lesion Models in Preoperative Assessment NCT06147024 | Fu Jen Catholic University | N/A |
| Unknown | Aortopathy Relationship to Imagery and Kinocardiography Features (ARTIK) NCT06286358 | Université Libre de Bruxelles | — |
| Recruiting | Outcome of the Semibranch in Pararenal and Thoracoabdominal Aortic Pathologies. A Prospective, Multicentre Reg NCT06059053 | University Hospital Muenster | — |
| Recruiting | Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms NCT06365138 | University Hospital Augsburg | — |
| Unknown | CO2 Automated Angiographies With Fusion Imaging for Zero- or Near Zero- Contrast FEVAR. NCT06337890 | University of Bologna | — |
| Completed | Prevalence of Ascending Aortic Dilation in Sports Medicine NCT07050953 | University Hospital, Caen | — |
| Recruiting | Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic NCT06789809 | The Cleveland Clinic | N/A |
| Unknown | Pre-operative Screening of Functional Fragilities Before Open Aortic Surgery: a New Area NCT06201338 | University Paul Sabatier of Toulouse | — |
| Active Not Recruiting | Cerebral Protection in Aortic Arch Surgery NCT04966247 | Barts & The London NHS Trust | — |
| Unknown | The Enzen Trial: Comparison of Evar Endoprosthesis: Endurant Versus Zenith NCT05969782 | Hospital do Servidor Publico Estadual | — |
| Active Not Recruiting | Thoraflex Hybrid and Relay Extension Post-Approval Study NCT05639400 | Vascutek Ltd. | — |
| Completed | Measurement of Heart-carotid Pulse Wave Velocity (hcPWV) by Laser Doppler Vibrometry (LDV) NCT05711693 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Recruiting | QoL After Complex Endovascular Aortic Repair NCT05774938 | Karolinska University Hospital | — |
| Unknown | Progression of Ascending Aorta Diameters in Bicuspid Aortic Valve After Transcatheter or Surgical Replacement. NCT05708118 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Unknown | LANDMARC Study: a Study With Focus on Aorta Ascendens NCT05655767 | Maastricht University Medical Center | — |
| Not Yet Recruiting | Safety and Effectiveness of Surgeon-Modified Stent Grafts forTreatment of Complex Aortic Aneurysms NCT05531084 | Jesse Manunga, MD | N/A |
| Completed | Validation of a Software and the Follow-up of Anteropoterior Migration of Stent NCT05287828 | Nurea | — |
| Unknown | Clinical Investigation of Clinical Safety and Performance of the SP-GRIPFLOW, Selective Cerebral Perfusion Cat NCT05421130 | Fuji Systems Corporation | N/A |
| Completed | Anatomical Feasibility of an Off-the-shelf Scalloped Stent-graft for Infrarenal Abdominal Aneurysm With a Host NCT05150873 | Azienda Ospedaliero-Universitaria di Modena | — |
| Unknown | Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR. NCT05073991 | Mahidol University | — |
| Active Not Recruiting | PMCF Study in Patients With Acute or Chronic Aortic Dissection or Aortic Aneurysm Treated With E-vita OPEN NEO NCT04986709 | JOTEC GmbH | — |
| Completed | Saline Flush to Reduce the Amount of Residual Air Inside a Stentgraft Delivery System NCT04909190 | Semmelweis University Heart and Vascular Center | N/A |
| Terminated | Use of Sublingual Microcirculation and FloTrac Monitoring During Major Vascular Surgery and Its Effect on Hosp NCT04913493 | Universitair Ziekenhuis Brussel | N/A |
| Completed | Biomarkers in Thoracic Aorta Surgery NCT04689139 | Petrovsky National Research Centre of Surgery | N/A |
| Unknown | Comparison of Aorto-iliac Endovascular Interventions With and Without the EndoNaut Workstation NCT04714268 | Therenva | — |
| Active Not Recruiting | A PMCF Study in Patients With Acute or Chronic Aortic Dissection or Aortic Aneurysm Treated With E-vita OPEN N NCT04676672 | JOTEC GmbH | — |
| Completed | Mild vs Moderate Hypothermic Circulatory Arrest With Unilateral Anterograde Cerebral Perfusion in Hemiarch Rep NCT04569864 | Tomsk National Research Medical Center of the Russian Academy of Sciences | N/A |
| Recruiting | NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness NCT04471909 | Endospan Ltd. | N/A |
| Recruiting | Phenotyping Heterogeneity and Regionality of the Aorta NCT05603520 | Heinrich-Heine University, Duesseldorf | — |
| Unknown | Left Renal Vein Division for Juxtarenal Aortic Exposure NCT05054972 | Medical University of Vienna | — |
| Recruiting | Patient Specific Biomechanical Modeling of Abdominal Aortic Aneurysm to Improve Aortic Endovascular Repair NCT03481075 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Terminated | HAART Annuloplasty Device Valve Repair Registry NCT04035356 | Biostable Science & Engineering | — |
| Unknown | Secondary Rupture of Aortic Aneurysm Post EVAR NCT04507334 | Central Hospital, Nancy, France | — |
| Completed | Elective Treatment Rates and Surgical Non-eligibility Among Men and Women With Intact Abdominal Aortic Aneurys NCT05346289 | Karolinska University Hospital | — |
| Unknown | Evaluation of Adjunctive EndoAnchors for EVAR and TEVAR NCT04100499 | Hospital Universitario Ramon y Cajal | — |
| Enrolling By Invitation | Prospective Aortic Biobank of POP-STAR NCT04269447 | Karolinska University Hospital | — |
| Unknown | Safety and Efficacy of the Gore® Excluder® Iliac Branch Platform and Analysis of Its Behavior in Combination W NCT04356313 | Asociacion para el Estudio de la Enfermedades Vasculares de Galicia | — |
| Completed | Evaluation of the Effectiveness of Ischemic Pre-conditioning on the Morbidity and Mortality of Open Surgery of NCT03718312 | University Hospital, Rouen | N/A |
| Completed | ELECT Trial - Embolization of the Lumbar Arteries Before EVAR NCT03842930 | University of Leipzig | N/A |
| Completed | Evaluation of the Accuracy of the Vessel Navigator Tool for Catheterization of Supra-aortic Vessels - ARCHIBAL NCT03269734 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Completed | Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels NCT03727542 | Istanbul University | N/A |
| Active Not Recruiting | Identification of Genetic Causes of Calcific Aortic Valve Disease NCT04149600 | Beth Israel Deaconess Medical Center | — |
| Completed | Freestyle Prosthesis for Aortic Root-replacement With and Without Hemiarch Replacement NCT04068337 | Triemli Hospital | — |
| Unknown | Longitudinal Registry of Endovascular Thoracoabdominal Aneurysms NCT03499431 | Tara Mastracci | — |
| Completed | AoA Guided Thoracic Epidural Analgesia for Abdominal Aortic Repair NCT06609993 | Michał Stasiowski | N/A |
| Active Not Recruiting | Early Feasibility Study of the RelayBranch Thoracic Stent-Graft System NCT03214601 | Bolton Medical | N/A |
| Unknown | A Laboratory Scan of Patients With Aortic Aneurysms to IgG4 Levels in the Blood NCT03267875 | Meir Medical Center | N/A |
| Completed | Autophagy, Oxidative Stress and Hippo Signaling in Human Aortic Aneurysm NCT03211000 | Neuromed IRCCS | — |
| Unknown | Organ Failure After Advanced Endovascular Thoracoabdominal Aortic Surgery NCT03136536 | Region Örebro County | — |
| Completed | Effect of Remote Ischemic Preconditioning on the Incidence of Contrast Induced Nephropathy in Patients Undergo NCT05350683 | Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery | Phase 2 |
| Completed | Different Antihypertensive Drugs on Aortic Diseases NCT06626607 | Eighth Affiliated Hospital, Sun Yat-sen University | — |
| Completed | Blood microRNA Depression Change After DHCA NCT03339414 | China International Neuroscience Institution | — |
| Completed | Modern Technology For Learning and Psychosocial Support In Patients With Abdominal Aortic Aneurysm NCT03157973 | Karolinska University Hospital | N/A |
| Unknown | Role of Circulating MicroRNAs in Pathogenesis of Aneurysms of the Abdominal and Thoracic Aorta - Study "Micro NCT03090763 | Charles University, Czech Republic | — |
| Unknown | Intraoperative Nasal Insulin Effect on Plasma and CSF Insulin Concentration and Blood Glucose NCT02729064 | Hiroaki Sato, MD., PhD. | Phase 1 |
| Completed | Thoraflex™ Hybrid IDE Study NCT02724072 | Bolton Medical | N/A |
| Completed | Economic Comparison of Percutaneous (pEVAR) vs. Open Access in EVAR. NCT02822560 | Wilhelminenspital Vienna | N/A |
| Completed | Point of Care 3D Ultrasound for Various Applications: A Pilot Study NCT02831556 | Duke University | — |
| Recruiting | Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease NCT04005976 | The University of Texas Health Science Center, Houston | — |
| Terminated | Prehabilitation for Aortic Repair Patients NCT02767518 | University of Michigan | N/A |
| Completed | Computed Tomography Arteriograms (CTA) Volume Dose Reduction Study NCT02669784 | Milton S. Hershey Medical Center | N/A |
| Unknown | Evaluation of Aortic Aneurysms With Focus on Wall Stress and Wall Rupture Risk NCT02800876 | University of Zurich | — |
| Unknown | Validation of the Cheetah NICOM by Comparison to TEE During Open Vascular Surgery - Pilot Study NCT02630550 | Maisonneuve-Rosemont Hospital | — |
| Completed | A Case Control Observational Study to Assess CYDAR Automated Overlay Guidance During EVAR NCT02592733 | Royal Free Hospital NHS Foundation Trust | — |
| Completed | Implementation of Non-size Markers Derived From 4D Flow MRI of Patients With Aortic Disease. NCT02467062 | Universitair Ziekenhuis Brussel | N/A |
| Completed | Dynamic CT Imaging After Nellix Endoprosthesis Implantation NCT02438605 | Rijnstate Hospital | — |
| Recruiting | Multidisciplinary Analysis by Morphological and Mechanical Evaluation of the Aortic Wall in Patients Undergoin NCT07422129 | Fondazione IRCCS Policlinico San Matteo di Pavia | — |
| Completed | Matrix Aging and Aneurysm NCT02784769 | CHU de Reims | N/A |
| Completed | Characterization of Aortic Tissue at Reoperation NCT02375542 | CryoLife Europa | — |
| Completed | PET-CT After Nellix Implantation NCT02349100 | Rijnstate Hospital | — |
| Completed | Trimodal Prehabilitation for Aneurysm Surgery Study NCT02292927 | Imperial College London | N/A |
| Completed | RE-GENERATION: The Safety and Performance of the Relay Pro and Relay NBS Pro Stent-graft Devices in the Europe NCT03207568 | Bolton Medical | N/A |
| Completed | Dual Energy CT Urography With Reduced Iodinated Contrast NCT02283307 | University of Washington | N/A |
| Completed | Is Obstructive Sleep Apnoea a Risk Factor for Thoracic Aortic Aneurysm Expansion? A Prospective Cohort Study. NCT02204774 | University of Zurich | — |
| Unknown | Safety and Efficacy of Multiple Overlapping Uncovered Stents for Pararenal Aortic Aneurysm Repair NCT01985906 | Changhai Hospital | N/A |
| Completed | Patient Tailored Contrast Volume for Preoperative CT Angiography of the Aorta NCT05716568 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Recruiting | Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study NCT03233087 | Beijing Institute of Heart, Lung and Blood Vessel Diseases | — |
| Completed | Post-market Observational Study Zenith® t-Branch™ NCT02104089 | Cook Group Incorporated | — |
| Terminated | The CardioPAT Project: A Randomized Trial NCT02058134 | Rigshospitalet, Denmark | N/A |
| Unknown | Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aorti NCT01678274 | University of Aarhus | — |
| Unknown | Reference Values of Circulating Endothelial Progenitor Cells NCT01918969 | Hopital Jean Minjoz | — |
| Unknown | Circulating Endothelial Progenitor Cells and Aortic Aneurysm NCT01918982 | Hopital Jean Minjoz | — |
| Completed | Clinical Evaluation of a Modular Extracorporeal Circulation Circuit NCT02000544 | AHEPA University Hospital | N/A |
| Completed | Microcirculation and Anesthesia in Vascular Surgery NCT03510793 | Università Politecnica delle Marche | — |
| Recruiting | Cardiovascular Health Improvement Project NCT02306200 | University of Michigan | — |
| Completed | Platelet Activity in Vascular Surgery for Thrombosis and Bleeding NCT01897103 | NYU Langone Health | — |
| Completed | X-chromosome Inactivation, Epigenetics and the Transcriptome NCT01678261 | University of Aarhus | — |
| Completed | Zenith® p-Branch™: Single-Center Study NCT01663064 | Cook Group Incorporated | N/A |
| Completed | ANCHOR (Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System Global Registry) NCT01534819 | Medtronic Cardiovascular | — |
| Completed | Aortic Cross-Clamping and Systemic Inflammatory Response in Humans: Effect of Ischemic Preconditioning NCT02570464 | University Hospital, Rouen | N/A |
| Completed | Endurant™ Stent Graft System in the Treatment of Infra-renal Abdominal Aortic Aneurysms (ENDURANT France) NCT01526811 | Medtronic Cardiovascular | — |
| Completed | Endoleak Repair Guided by Navigation Technology NCT01843322 | Norwegian University of Science and Technology | N/A |
| Completed | Study of Post-operative Oxygen Consumption Following Vascular Surgery NCT01327820 | NHS Lothian | — |
| Unknown | Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm NCT01523262 | Aarhus University Hospital | Phase 1 |
| Terminated | Long-term Benefit of Aortic Stent-graft in Patients With Distal Aortic Dissection NCT01354119 | Asan Medical Center | Phase 4 |
| Completed | Computed Tomography Dose Reduction Using Sequential or Fast Pitch Sprial Technique NCT01272453 | Gilbert L. Raff, MD | — |
| Completed | An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Su NCT01256372 | Action Pharma A/S | Phase 2 |
| Terminated | Cook Iliac Branch Graft Post-market Registry NCT01055275 | Cook Group Incorporated | — |
| Withdrawn | ATLANTIS:Extensive Type A Dissections and Thoracic/ Thoraco-Abdominal Aneurysms Repair With LupiAe Hybrid Tech NCT01107366 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Phase 4 |
| Completed | TX2® Low Profile TAA Endovascular Graft NCT01151020 | Cook Research Incorporated | N/A |
| Terminated | A Safety and Efficacy Study of Blood Pressure Control in Acute Aortic Emergencies - A Pilot Study (PROMPT) NCT01033370 | Asma Zainab, M.D. | Phase 4 |
| Unknown | Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Thoracal Abdominal Ane NCT01354821 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Prevention of Incisional Hernia by Mesh Augmentation After Midline Laparotomy for Aortic Aneurysm Treatment NCT00757133 | University Hospital, Ghent | N/A |
| Completed | Magnetic Resonance Imaging of Aortic Aneurysm Instability NCT00794092 | University of Edinburgh | Phase 2 / Phase 3 |
| Completed | Haemocomplettan® P During Aortic Replacement NCT00701142 | CSL Behring | Phase 2 |
| Unknown | PET/CT Imaging of Aneurysm Wall Inflammation NCT00661518 | Radboud University Medical Center | — |
| Completed | Prevention of Colon Ischemia During Aortic Aneurysm (AAA) Repair NCT00671203 | Spectros Corporation | Phase 3 |
| Completed | Conservative Aortic Valve Surgery for Aortic Insufficiency and Aneurysms of the Aortic Root. CAVIAAR NCT00478803 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion NCT00494598 | Columbia University | — |
| Completed | Melatonin and Cardiac Outcome After Major Surgery NCT00315926 | University Hospital, Gentofte, Copenhagen | Phase 2 / Phase 3 |
| Unknown | Dynamic Computed Tomography Angiography (CTA) Follow-up for EndoVascular Aortic Replacement (EVAR) NCT00680004 | Radboud University Medical Center | — |
| Completed | Fast Track Management in Elective Open Infrarenal Aortic Aneurysm Repair NCT00615888 | University of Ulm | N/A |
| Completed | Adjunctive Treatment With Doxycycline to Enhance the Durability of Endovascular Aortic Aneurysm Repair NCT00126204 | The Foundation for Barnes-Jewish Hospital | N/A |
| Completed | Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA) NCT00094575 | VA Office of Research and Development | Phase 4 |
| Unknown | Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques NCT00449306 | Sheba Medical Center | — |
| Unknown | Abdominal Aortic/Aorto-Iliac Aneurysm Endoluminal Graft Study NCT00549354 | Arizona Heart Institute | Phase 2 |
| Completed | Study of the Influence of the Moon and Seasons On Outcomes Following Surgery To Repair Ascending Aortic Dissec NCT02236923 | 22EON | — |
| Approved For Marketing | Zenith® TX2® Low Profile TAA Endovascular Graft NCT02471781 | Cook Group Incorporated | — |