NCT01523262

Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm

The Effect of Preconditioning to Prevent Perioperative Myocardial Ischemia in Elective Operation of Abdominal Aortic Aneurysm

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Aarhus University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Primary To investigate whether peripheral predonditioning induced by brief, intermittent constriction of blood supply to an arm can reduce the incidence of perioperative myocardial ischemia in patients operated electively for infrarenal aortic aneurysm. Secondary To investigate the impact of peripheral preconditioning on perioperative inflammatory response. To investigate whether peripheral preconditoning can protect against perioperative myocardial infarction and reduced cardiac pump function.

Conditions

• Aortic Aneurysm

Interventions

Type	Name	Description
PROCEDURE	preconditioning	peripheral preconditioning induced by brief, intermittent constriction of blood supply to an arm
PROCEDURE	Normal surgery, with sham intervention without inflating arm cuff

Timeline

• Start date: 2011-01-01
• Primary completion: 2015-01-01
• Completion: 2016-01-01
• First posted: 2012-02-01
• Last updated: 2015-01-14

Locations

2 sites across 1 country: Denmark