| Not Yet Recruiting | Therapeutic Benefits of a Motor Imaging Protocol Following Anterior Cruciate Ligament Reconstruction Surgery NCT07210489 | GCS Ramsay Santé pour l'Enseignement et la Recherche | N/A |
| Not Yet Recruiting | Prognosis Analysis of Three Surgical Techniques for Arthroscopic Anterior Cruciate Ligament Reconstruction NCT06891430 | Beijing Tsinghua Chang Gung Hospital | N/A |
| Recruiting | Vitamin D to Improve Quadricep Muscle Strength NCT05174611 | Chinese University of Hong Kong | Phase 2 |
| Enrolling By Invitation | A Study to Evaluate the Incrediwear Products Immediately After ACL Repair NCT06668376 | Texas Bone and Joint | N/A |
| Recruiting | Over-the-Top vs. Anteromedial ACLR With Lateral Extraarticular Tenodesis NCT06664047 | Ankara City Hospital Bilkent | N/A |
| Recruiting | Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction NCT06511232 | The Methodist Hospital Research Institute | Phase 4 |
| Active Not Recruiting | Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Fo NCT06524349 | Sanford Health | N/A |
| Recruiting | Bone Marrow Aspirate Concentrate for Anterior Cruciate Ligament Tear Treatment. NCT06353503 | abdulmajeed hammadi | N/A |
| Unknown | Effect of Physical Therapy and/or Platelet Rich Plasma Injection in People With Knee Cruciate Ligament Injurie NCT06233305 | Taipei Hospital, Ministry of Health and Welfare | — |
| Recruiting | Tunnel Widening in Augmented ACL Integration Via PrP Enriched Collected Autologous Bone vs Standard ACL Techni NCT05953051 | Schulthess Klinik | N/A |
| Recruiting | Effect of ACL Reconstruction in Biomechanical Properties of Ankle Joint Complex NCT06631690 | Cairo University | N/A |
| Recruiting | Exploring Prolonged AMR in ACL Reconstructed Patients NCT06430775 | University Ghent | — |
| Withdrawn | Bilateral Versus Unilateral Strength Training After ACLR NCT06032247 | University of Kansas | N/A |
| Terminated | Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee NCT05204836 | University of Calgary | Phase 1 |
| Completed | Arthrometry and Clinical Tests for Diagnosing ACL Tears NCT05416632 | Liverpool University Hospitals NHS Foundation Trust | N/A |
| Unknown | The Effect of Perioperative and Postoperative Music Reduces Pain Perception After Anterior Cruciate Ligament R NCT06275828 | Police General Hospital, Thailand | N/A |
| Completed | Comparison of Two ACL Reconstruction Techniques: All-inside Versus Complete Tibial Tunnel Technique NCT05574946 | Samsun University | N/A |
| Unknown | Physical Activity, Knee Joint Loading and Joint Health NCT05306054 | University of Bath | — |
| Recruiting | Vibration on Patellofemoral Joint Pain After ACLR NCT05501210 | Chinese University of Hong Kong | N/A |
| Unknown | Comparative Evaluation of Functional Results and Survival Rate of Peroneus Longus Tendon - PLT and Hamstring T NCT05579067 | eMKa MED Medical Center | N/A |
| Completed | External Focus of Attention Posttraumatic Osteoarthritis NCT04922268 | University of North Carolina, Charlotte | N/A |
| Completed | The Effectıveness Of Structured Myofascial Chain Exercise Training After Anterior Cruciate Ligament Reconstruc NCT05423184 | Bahçeşehir University | N/A |
| Active Not Recruiting | Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair NCT05494073 | Henry Ford Health System | N/A |
| Completed | Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque NCT05109871 | Liverpool University Hospitals NHS Foundation Trust | N/A |
| Completed | The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study NCT04956393 | University of British Columbia | N/A |
| Active Not Recruiting | A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction NCT03776162 | The Cleveland Clinic | N/A |
| Unknown | Reconstruction of the Anterior Cruciate Ligament of the Knee Joint, by the Method of Stabilization of the Scre NCT05328544 | eMKa MED Medical Center | N/A |
| Completed | Werewolf Flow 50 During ACL Reconstruction NCT04998656 | University of Colorado, Denver | N/A |
| Completed | Long Term Clinical and Radiographical Outcomes of Different Anterior Cruciate Ligament Reconstruction Techniqu NCT05088278 | Istituto Ortopedico Rizzoli | N/A |
| Unknown | Assessment of the Safety and Performance of Knee Ligament Supports in the Context of a Return to Sport After S NCT04592471 | Decathlon SE | — |
| Completed | Quantifying the Benefits of Supervised vs. Unsupervised Pre-habilitation for Patients With Acute ACL Tears NCT04593264 | WellSpan Health | N/A |
| Unknown | Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction NCT04764916 | Carilion Clinic | Phase 3 |
| Completed | Anterior Cruciate Ligament Reconstruction With and Without Lateral Extra-Articular Tenodesis Among High Demand NCT05962580 | Ain Shams University | N/A |
| Unknown | Anterior Cruciate Ligament Reconstruction With Quadriceps Tendon Bone Autograft NCT05673356 | Artromedical Konrad Malinowski Clinic | N/A |
| Terminated | Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury NCT04331002 | Austin V Stone | Phase 2 |
| Active Not Recruiting | Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial NCT04039971 | University of Colorado, Denver | N/A |
| Completed | Use of Blood Flow Restriction Therapy Following ACL Tear NCT04374968 | Henry Ford Health System | N/A |
| Unknown | Analysis of Radiological Features of Lateral Femoral Impaction Fracture / Lateral Femoral Notch Sign NCT05682820 | Artromedical Konrad Malinowski Clinic | — |
| Recruiting | SEQUAR SEmitendinosus vs QUadriceps in Anterior Cruciate Ligament Reconstruction NCT04295148 | Karolinska Institutet | N/A |
| Completed | Primary Anterior Cruciate Ligament Repair With and Without Lateral Extraarticular Tenodesis NCT05923710 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | N/A |
| Terminated | Treatment of Acute ACL Injuries in Young Patients Using a Rebound ACL Brace NCT04185532 | Frida Hansson, MD | N/A |
| Unknown | The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults NCT04178538 | Marshall University | N/A |
| Completed | Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears NCT04088227 | Andrews Research & Education Foundation | Phase 2 |
| Terminated | IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction NCT03983941 | Sujana Dontukurthy | Phase 3 |
| Terminated | IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions NCT02930122 | Cale Jacobs, PhD | Phase 2 |
| Completed | A New Etiological Cause for Anterior Cruciate Ligament Injury: E-Scooter NCT04960020 | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | — |
| Completed | Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation NCT04635579 | University of Washington | N/A |
| Terminated | Moderated Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction NCT02911909 | University of Missouri-Columbia | N/A |
| Active Not Recruiting | Bridge-Enhanced ACL Repair vs ACL Reconstruction NCT02664545 | Miach Orthopaedics | N/A |
| Completed | Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength NCT05190120 | University of California, San Francisco | Phase 4 |
| Completed | Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique NCT02760589 | AUVA | — |
| Active Not Recruiting | Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial) NCT02292004 | Miach Orthopaedics | N/A |
| Completed | Regenexx™ SD Versus Exercise Therapy for ACL Tears NCT01850758 | Regenexx, LLC | N/A |
| Completed | Dynamic Knee Laxity Measurement Coupled to MRI in Cases of Suspected Partial Anterior Cruciate Ligament Tear NCT02787096 | Hospices Civils de Lyon | N/A |
| Completed | Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing NCT01580722 | Isfahan University of Medical Sciences | Phase 2 |
| Completed | Prospective Femoral Versus Femoral and Sciatic Nerve Block for Anterior Cruciate Ligament (ACL) Reconstruction NCT01447277 | University of California, San Francisco | N/A |
| Unknown | Anterior Cruciate Ligament (ACL) Reconstruction: Single Bundle Versus Double Bundle NCT01025895 | Assaf-Harofeh Medical Center | Phase 4 |
| Completed | Prospective Registry of Anterior Cruciate Ligament Reconstructions NCT04135950 | State University of New York at Buffalo | — |
| Completed | Evaluation of Biocleanse Allografts For ACL Reconstruction NCT00187876 | University of Florida | Phase 4 |