NCT06353503

Bone Marrow Aspirate Concentrate for Anterior Cruciate Ligament Tear Treatment.

Using Autologous Bone Marrow Aspirate Concentrate to Treat Complete Anterior Cruciate Ligament Tear.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: abdulmajeed hammadi · Industry
• Sex: All
• Age: 20 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

A single armed multicenter study enrolling 20 patients using autologous bone marrow aspirate concentrate (which is done under local or general anesthesia to aspirate around 1-2 cc/kg body weight then concentration which is done by using centrifugation and special disposable kit) local injection of 4 cc per joint under ultrasonic guidance ,completely sterile field with local anesthesia.

Detailed description

The anterior cruciate ligament (ACL) is key to the functional stability of the knee joint and is highly susceptible to injury, especially in athletes engaged in high-impact sports. Conventional treatment for partial tears may involve conservative management; however, complete tears often necessitate surgical reconstruction. In seeking alternative treatments, this study investigates the potential of bone marrow aspirate concentrate BMAC-a regenerative medicine approach-to promote healing and restore functionality to completely torn ACLs. The regenerative properties of BMAC, attributed to the presence of stem cells and growth factors, may facilitate ligament repair and regeneration. the team aim treating 1st and 2nd degree anterior cruciate ligament tear without retraction.

Conditions

• Anterior Cruciate Ligament Tear

Interventions

Type	Name	Description
PROCEDURE	autologous bone marrow aspirate concentrate	local knee joint injection of autologous bone marrow

Timeline

• Start date: 2024-04-02
• Primary completion: 2026-09-27
• Completion: 2026-09-27
• First posted: 2024-04-09
• Last updated: 2025-08-07

Locations

1 site across 1 country: Iraq