| Recruiting | Optimizing Pain Treatment in Children On Mechanical Ventilation NCT06994442 | Weill Medical College of Cornell University | Phase 3 |
| Recruiting | The Effects of Transversalis Fascia Plane Block on Opioid Consumption in Patients Undergoing Hand-Assisted Lap NCT07396753 | Koç University | N/A |
| Recruiting | Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pai NCT06878014 | Medical University of Silesia | Phase 4 |
| Not Yet Recruiting | ED50 of Sufentanil for Intraoperative Analgesia NCT06662656 | China International Neuroscience Institution | — |
| Recruiting | Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Inductio NCT06487988 | American University of Beirut Medical Center | N/A |
| Enrolling By Invitation | Alternatives to Dental Opioid Prescribing After Tooth Extraction NCT06275191 | Douglas Oyler | N/A |
| Completed | Comparison of Total Intravenous Anesthesia and Inhalational Anesthesia in Opioid-Free Anesthesia for Bariatric NCT06390046 | Jagiellonian University | N/A |
| Recruiting | Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery NCT06380244 | Jagiellonian University | N/A |
| Recruiting | IPACK on Early Pain Scores After ACL Reconstruction NCT05985629 | Loyola University | Phase 4 |
| Completed | Opioid Use of Local Anaesthetic Agents in Open Heart Surgery and Its Effect on Recovery NCT06642077 | Yuzuncu Yil University | N/A |
| Recruiting | Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients Wit NCT05842928 | Ludwig-Maximilians - University of Munich | N/A |
| Completed | Perioperative Methadone in Hip Fracture Patients NCT05581901 | University of Southern Denmark | Phase 4 |
| Unknown | Multimodal Analgesic Management of Naborphine Combined With Opioid Free Anesthesia in OSA Patients Undergoing NCT05386979 | Qianfoshan Hospital | N/A |
| Completed | Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study NCT05099055 | St. Justine's Hospital | Phase 3 |
| Withdrawn | Rescue Quadratus Lumborum Blocks for Post-cesarean Pain NCT04397458 | The University of Texas Health Science Center, Houston | Phase 4 |
| Completed | Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass NCT05004519 | matthieu clanet | N/A |
| Unknown | Phase 1: Randomized Evaluation of a System to Deliver Mobile Cognitive Behavioral Therapy NCT04836169 | InCaveo | N/A |
| Unknown | Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery NCT04144933 | University of Saskatchewan | Phase 3 |
| Completed | Totally Transdermal Sedation in the Weaning From Remifentanil Infusion NCT04204967 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Phase 2 |
| Completed | Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine NCT04369950 | The University of Texas Health Science Center, Houston | Phase 4 |
| Withdrawn | A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture NCT02985177 | St. Justine's Hospital | Phase 4 |
| Completed | A Strategy to Reduce Opioid Drug Prescribing by Clinicians NCT03809507 | University of North Carolina, Chapel Hill | — |
| Completed | Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fent NCT03858621 | Victor Contreras, MSN | N/A |
| Active Not Recruiting | Tapering From Long-term Opioid Therapy in Chronic Pain Population. Randomized Controlled Trial With 12 Months NCT03485430 | Lund University Hospital | N/A |
| Completed | Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectom NCT03294109 | University of California, Los Angeles | Phase 4 |
| Unknown | A Patient Education Video Program for Post-Operative Recovery After Upper Extremity Surgery NCT03366805 | Carilion Clinic | N/A |
| Completed | Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Ton NCT02987985 | University of Saskatchewan | Phase 3 |
| Completed | Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair NCT03380533 | Hospital Italiano de Buenos Aires | Phase 2 / Phase 3 |
| Withdrawn | Improving Pain Relief Following Laparoscopic Ventral Hernia Repair NCT02785276 | University of Auckland, New Zealand | N/A |
| Completed | Pain and Narcotic Usage After Orthopaedic Surgery NCT03991546 | Christopher Anthony | N/A |
| Completed | Shared Decision Making for Prescription Opioids After Cesarean Delivery NCT02770612 | Massachusetts General Hospital | N/A |
| Completed | A Quality Improvement Project to Investigate Individual Provider Variation in Opioid Prescribing From the Emer NCT02665429 | University of Massachusetts, Worcester | N/A |
| Completed | Opioid Free Anesthesia in Thoracic Surgery NCT04355468 | Medical University of Silesia | N/A |
| Completed | A Study of OROS Hydromorphone HCL vs Morphine in Cancer Pain Patients. NCT00410540 | Alza Corporation, DE, USA | Phase 3 |
| Completed | A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients Wi NCT00411034 | Alza Corporation, DE, USA | Phase 3 |
| Completed | Safety and Tolerability of Long-term Administration of OROS Hydromorphone HCI (Slow Release) in Cancer Pain NCT00410787 | Alza Corporation, DE, USA | Phase 3 |
| Completed | Safety and Tolerability of Long-Term Administration of Hydromorphone HCI CR (Controlled Release) NCT00410748 | Alza Corporation, DE, USA | Phase 3 |
| Completed | A Repeated Dose Study of the Metabolism and Action Evaluation of OROS Hydromorphone HCI (Slow Release) Tablets NCT00410878 | Alza Corporation, DE, USA | Phase 1 |