Clinical Trials Directory

Trials / Conditions / Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors

71 registered clinical trials studyying Advanced or Metastatic Solid Tumors20 currently recruiting.

StatusTrialSponsorPhase
RecruitingPRISM-NK: Precision-Matched Allogeneic Single- or Dual-Target CAR-NK Cells for Advanced Solid Tumors
NCT07510828
Beijing BiotechPhase 1 / Phase 2
RecruitingA Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors
NCT07205718
TakedaPhase 1 / Phase 2
Active Not RecruitingA Phase 1b/2 Multisite Dose-finding and Expansion Study of WTX-330 in Adult Patients With Selected Advanced or
NCT06939283
Werewolf Therapeutics, Inc.Phase 1 / Phase 2
Not Yet RecruitingA Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors
NCT06389526
Coherus Oncology, Inc.Phase 1
RecruitingSafety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors
NCT06781983
Innate PharmaPhase 1
RecruitingA Phase 1 Study of LNCB74 in Advanced Solid Tumors
NCT06774963
NextCure, Inc.Phase 1
RecruitingDose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tum
NCT06724016
Hanmi Pharmaceutical Company LimitedPhase 1
RecruitingA Phase I Study to Investigate the Safety and Tolerability of KGX101 Monotherapy and Combination Therapy With
NCT07260305
Kangabio AUSTRALIA LTD PTYPhase 1
RecruitingTo Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With L
NCT06752681
Day One Biopharmaceuticals, Inc.Phase 1
RecruitingA Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
NCT06395519
858 Therapeutics, Inc.Phase 1 / Phase 2
TerminatedA Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combi
NCT06448364
PfizerPhase 1
Active Not RecruitingA Phase I Study of ONO-4538HSC in Subjects With Advanced or Metastatic Solid Tumors
NCT06548217
Ono Pharmaceutical Co., Ltd.Phase 1
TerminatedA Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors
NCT06257758
Valerio TherapeuticsPhase 1 / Phase 2
RecruitingA Phase 1 Study to Evaluate TGI-6 in Subjects With Locally Advanced/Metastatic Solid Tumors
NCT06374173
Hefei TG ImmunoPharma Co., Ltd.Phase 1
RecruitingStudy to Assess the Safety, Tolerability, and Blood Concentration of PMC-309
NCT05957081
PharmAbcinePhase 1
RecruitingDose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumo
NCT06234397
Hanmi Pharmaceutical Company LimitedPhase 1
Active Not RecruitingThis is an Open Label, Two-part, Multicenter, Phase I Trial to Investigate the Safety, Tolerability, and PK of
NCT06074497
Kangabio AUSTRALIA LTD PTYPhase 1
UnknownPhase I of XKH002 Injection in Patients
NCT06196762
Zhejiang Kanova Biopharmaceutical Co., LTDPhase 1
RecruitingA Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors
NCT06248411
Kyowa Kirin Co., Ltd.Phase 1
Active Not RecruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations
NCT05907304
Erasca, Inc.Phase 1
RecruitingDCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors
NCT05785754
DynamiCure BiotechnologyPhase 1
RecruitingA Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
NCT05787587
IDEAYA BiosciencesPhase 1
RecruitingA First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies
NCT05753722
Incendia TherapeuticsPhase 1
CompletedAssessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid
NCT05848466
Bio-Thera SolutionsPhase 1
TerminatedA Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors
NCT05716295
Medikine, Inc.Phase 1 / Phase 2
Not Yet RecruitingStudy of MHB088C in Participants With Advanced or Metastatic Solid Tumors
NCT05652855
Minghui Pharmaceutical Pty LtdPhase 1 / Phase 2
RecruitingPan-T Booster Co-expressing MSLN CAR T Cell Therapy in Advanced/Metastatic Solid Tumors
NCT05693844
Chinese PLA General HospitalPhase 1 / Phase 2
RecruitingDose Escalation and Expansion Study of HM97662 in Advanced or Metastatic Solid Tumors
NCT05598151
Hanmi Pharmaceutical Company LimitedPhase 1
CompletedA Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK
NCT05594043
Merck Sharp & Dohme LLCPhase 1
UnknownA Study to Investigate the Safety, Tolerability and Efficacy of HLX60 Combination With HLX10 in Subjects With
NCT05483530
Shanghai Henlius BiotechPhase 1
CompletedWTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma
NCT05678998
Werewolf Therapeutics, Inc.Phase 1
RecruitingA Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With A
NCT05538130
PfizerPhase 1
TerminatedDCBY02 as a Monotherapy in Patients With Advanced or Metastatic Solid Tumors
NCT05496595
DynamiCure BiotechnologyPhase 1
Active Not RecruitingA Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants with Advanced Unresectab
NCT05572684
NextCure, Inc.Phase 1 / Phase 2
UnknownTo Evaluate the Safety and Tolerability of SYHX2001 in Patients With Advanced or Metastatic Solid Tumors
NCT05407909
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.Phase 1
Active Not RecruitingA Dose Escalation and Expansion Study of TAC-001 in Patients With Select Advanced or Metastatic Solid Tumors
NCT05399654
Tallac TherapeuticsPhase 1 / Phase 2
Active Not RecruitingA Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic So
NCT05382325
Merck Sharp & Dohme LLCPhase 1
TerminatedA Clinical Study to Evaluate the Safety and Tolerability of JS012 in Advanced or Metastatic Solid Tumors
NCT05388279
Shanghai Junshi Bioscience Co., Ltd.Phase 1
UnknownA Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK114
NCT05200273
AkesoPhase 1
WithdrawnA Safety and Tolerability Study of NC318 in Combination With Chemotherapy for Subjects With Advanced or Metast
NCT04430933
NextCure, Inc.Phase 1 / Phase 2
Active Not RecruitingA Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembroli
NCT05017012
Merck Sharp & Dohme LLCPhase 1
UnknownA Study of MRG004A in Patients With Tissue Factor Positive Advanced or Metastatic Solid Tumors
NCT04843709
Shanghai Miracogen Inc.Phase 1 / Phase 2
TerminatedA Safety and Tolerability Study of NC762 in Subjects With Advanced or Metastatic Solid Tumors
NCT04875806
NextCure, Inc.Phase 1 / Phase 2
Active Not RecruitingA Study of ERAS-007 as Monotherapy or in Combination With ERAS-601 in Patients With Advanced or Metastatic Sol
NCT04866134
Erasca, Inc.Phase 1 / Phase 2
Active Not RecruitingA Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors
NCT04670679
Erasca, Inc.Phase 1
CompletedA Study of AK119 (Anti-CD73) in Combination With AK104 in Subjects With Advanced Solid Tumors
NCT04572152
AkesoPhase 1
TerminatedA Study of TAS0612 in Participants With Advanced or Metastatic Solid Tumor Cancer
NCT04586270
Taiho Oncology, Inc.Phase 1
CompletedA Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors
NCT04381650
TakedaPhase 1 / Phase 2
TerminatedA Study of Surufatinib Plus Sintilimab in Patients With Advanced Solid Tumor
NCT04427774
Innovent Biologics (Suzhou) Co. Ltd.Phase 1
TerminatedA Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors
NCT04408599
NextCure, Inc.Phase 1 / Phase 2
TerminatedEfficacy and Safety of Pemigatinib in Participants With Solid Tumors With FGFR Mutations or Translocations (FI
NCT04003623
Incyte CorporationPhase 2
CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tum
NCT03849469
Xencor, Inc.Phase 1
CompletedFirst-in-human Study of CA102N Monotherapy and CA102N Combined With Trifluridine/Tipiracil (LONSURF) in Subjec
NCT03616574
Holy Stone Healthcare Co., LtdPhase 1
TerminatedIntratumoral Cavrotolimod Combined With Pembrolizumab or Cemiplimab in Patients With Merkel Cell Carcinoma, Cu
NCT03684785
Exicure, Inc.Phase 1 / Phase 2
CompletedPhase 1 Study of ONO-7475 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors
NCT03730337
Ono Pharmaceutical Co., Ltd.Phase 1
CompletedA Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors
NCT03665285
NextCure, Inc.Phase 1 / Phase 2
TerminatedOral Immunomodulatory Tyrosine Kinase Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors
NCT03454243
Hoffmann-La RocheEARLY_Phase 1
TerminatedA Study of a New Investigational Medicinal Product to Treat Patients with Advanced or Metastatic Solid Tumors
NCT03316638
Pierre Fabre MedicamentPhase 1 / Phase 2
CompletedA Study of PD-L1 Antibody KN035 in Japanese Subjects With Locally Advanced or Metastatic Solid Tumors
NCT03248843
3D Medicines (Sichuan) Co., Ltd.Phase 1
Active Not RecruitingStudy of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors
NCT03155061
Ono Pharmaceutical Co., Ltd.Phase 1
CompletedA Study of Varlitinib in Japanese Subjects With Advanced or Metastatic Solid Tumours
NCT03082053
ASLAN PharmaceuticalsPhase 1
CompletedA Phase I Study of TAS-102 in Solid Tumors
NCT02261532
Taiho Pharmaceutical Co., Ltd.Phase 1
CompletedA Study of Nivolumab by Itself or Nivolumab Combined With Ipilimumab in Patients With Advanced or Metastatic S
NCT01928394
Bristol-Myers SquibbPhase 1 / Phase 2
CompletedPhase I Clinical Study of Metatinib Tromethamine Tablet
NCT02004548
Jiangsu Simcere Pharmaceutical Co., Ltd.Phase 1
TerminatedE7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine Alone in Patients With
NCT01355302
Eisai Inc.Phase 1 / Phase 2
TerminatedA Study Evaluating the Bioavailability of Two Formulations of Linifanib and Food Effect on Pharmacokinetics of
NCT01506934
AbbottPhase 1
CompletedDose Escalation of Velcade Daily Dose in Patients With Solid Tumors
NCT02220049
Gustave Roussy, Cancer Campus, Grand ParisPhase 1
CompletedStudy of NMS-1286937 in Adult Patients With Advanced/Metastatic Solid Tumors
NCT01014429
Nerviano Medical SciencesPhase 1
CompletedA Phase I/II Clinical Trial of Vidaza With Abraxane in Patients With Advanced/Metastatic Solid Tumors and Brea
NCT00748553
University of UtahPhase 1 / Phase 2
CompletedA Dose Escalation Study of SF1126, a PI3 Kinase (PI3K) Inhibitor, Given By Intravenous (IV) Infusion in Patien
NCT00907205
Semafore PharmaceuticalsPhase 1
CompletedA Phase I Study of STA-5312 in Subjects With Advanced or Metastatic Solid Tumors
NCT00276913
Synta Pharmaceuticals Corp.Phase 1