Actinic Keratoses

97 registered clinical trials studyying Actinic Keratoses — 14 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Actinic Keratoses Treated With 5-fluorouracil Plus Aluminum NCT07401277	West Virginia University	Phase 1
Withdrawn	Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients NCT04329221	Massachusetts General Hospital	Phase 2
Withdrawn	Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients NCT04642287	Massachusetts General Hospital	Phase 2
Not Yet Recruiting	Efficacy and Safety of Cryotherapy Followed by Tirbanibulin Ointment for Actinic Keratosis on the Scalp and Fo NCT07273656	University Hospital, Lille	Phase 3
Not Yet Recruiting	PDT vs Peels for Treatment of Actinic Keratoses NCT04429308	Northwestern University	Phase 2
Completed	Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage NCT07053852	Sherrif Ibrahim	Phase 1
Not Yet Recruiting	Efficacy of Topical 5-Fluorouracil Vs Calcipotriol As Photodynamic Therapy Pre-treatment for Field Actinic Ker NCT06685588	St Vincent's University Hospital, Ireland	N/A
Not Yet Recruiting	Methyl Aminolevulinate 8% and 16% Incubated by 1 and 3 for Actinic Keratoses Treatment NCT06507644	University of Nove de Julho	N/A
Recruiting	Combination Therapy of 5-Fluorouracil and CALcipotriol Versus 5-Fluorouracil in the Treatment of Actinic Kerat NCT06499415	Maastricht University Medical Center	Phase 4
Completed	Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses NCT05923060	Case Comprehensive Cancer Center	Phase 2
Not Yet Recruiting	Efficacy And Safety Of Illumination Dose Reduction In Red Light Photodynamic Therapy For Actinic Keratoses NCT06545396	Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal	N/A
Enrolling By Invitation	Efficacy and Safety of Cryotherapy Versus 5-Fluorouracil in the Treatment of Actinic Keratosis NCT06461442	University of California, Davis	Phase 4
Completed	Evaluating an Artificial Intelligence Tool to Help Primary Care Doctors Diagnose Skin Conditions. NCT07428941	AI Labs Group S.L	—
Recruiting	Investigation of the Effect of Lipikar Baume AP+M NCT06385340	CentroDerm GmbH	N/A
Recruiting	Effect of Lipikar Urea 30% Before Actinic Keratoses Treatment NCT06274320	Cosmetique Active International	N/A
Recruiting	The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Popula NCT06428721	Wright State University	N/A
Recruiting	SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomograph NCT06321003	University of Palermo	—
Withdrawn	Tirbanibulin 1% Ointment for the Treatment of Actinic Keratosis on the Back of the Hands NCT06026358	Medical University of Graz	Phase 4
Completed	Impact of Madecassoside and 5 % Panthenol Cream in Post Photodynamic Therapy for Actinic Keratosis NCT05937529	Merete Haedersdal	N/A
Unknown	Cryotherapy in Combination with Red Light PDT for Actinic Keratosis of Full Face NCT06745999	Psoriasis Treatment Center of Central New Jersey	Phase 4
Completed	OCT and Invasion in Cutaneous Skin Lesions NCT06014697	Maastricht University Medical Center	—
Unknown	Gene and Protein Expression Profiles After Treatment of Actinic Keratoses NCT05740969	Ismail Gögenur	Phase 2
Active Not Recruiting	Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatmen NCT05662202	Biofrontera Inc.	Phase 3
Active Not Recruiting	Patient Decision Aid for the Treatment of Actinic Keratosis NCT06008171	Maastricht University Medical Center	N/A
Completed	ADL-PDT Under Routine Clinical Conditions in Patients With Actinic Keratosis NCT05725213	Galderma Laboratorium GmbH	—
Completed	Efficacy and Safety of Tixel Treatment on Facial and/or Scalp Actinic Keratoses. NCT05365386	Novoxel Ltd.	N/A
Active Not Recruiting	Impact of Human Papillomavirus (HPV) Vaccination on Burden of Disease in Patients with Actinic Keratosis NCT05202860	Merete Haedersdal	Phase 2
Completed	Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmace NCT05078827	Encube Ethicals Pvt. Ltd.	Phase 3
Completed	Comparison of Nicotinamide Treatments for Actinic Keratosis NCT07049068	Federal University of Rio Grande do Sul	Phase 1
Completed	Clinical Evaluation of a Short Illumination Duration (35 Minutes) When Performing PDT of AK Using the Dermaris NCT05522036	Centre Dermatologique du Roy	N/A
Unknown	Phase I/IIa Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-d NCT05164393	Coegin Pharma AB	Phase 1 / Phase 2
Completed	Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo NCT04969419	Momentum Data	—
Completed	Earliest Stage Treatment of Aktinic Keratosis With Imiquimod 3.75% Cream NCT04842422	Medical University of Graz	Phase 4
Terminated	Comparing Immune Responses to Topical Imiquimod NCT04809662	University of California, Davis	—
Active Not Recruiting	High- and Low-risk Actinic Keratosis Referrals to Secondary Care NCT05976061	Maastricht University Medical Center	—
Completed	Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emol NCT04875026	Pierre Fabre Medicament	Phase 4
Active Not Recruiting	The Influence of an E-learning Program on Recognition of Actinic Keratosis NCT05987553	Maastricht University Medical Center	—
Enrolling By Invitation	HRQoL Keratinocyte Carcinomas NCT04814953	University Hospital, Ghent	—
Completed	Evaluation of The Efficacy and Safety of Tixel Treatment for the Treatment of Facial and/or Scalp Actinic Kera NCT04527653	Novoxel Ltd.	N/A
Completed	Study to Evaluate the Safety of BF-200 ALA (Ameluz®) for Photodynamic Therapy (PDT) in the Treatment of Expand NCT04319159	Biofrontera Bioscience GmbH	Phase 1
Active Not Recruiting	Implementation of Actinic Keratosis Guideline Among General Practitioners. NCT05976048	Maastricht University Medical Center	—
Terminated	Duration of Ameluz Application in Acral Actinic Keratoses Response NCT03963102	Royal Cornwall Hospitals Trust	Phase 4
Completed	Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream NCT04085367	Galderma R&D	Phase 3
Terminated	Combination Topical Therapy for Treatment of Scalp Actinic Keratoses NCT03996252	Tulane University	EARLY_Phase 1
Completed	Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scal NCT03575780	Athenex, Inc.	Phase 1
Unknown	Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention NCT03642535	Shanghai Dermatology Hospital	Phase 4
Unknown	The Study of Plum-blossom Needling Enhancing Efficacy of Aminolevulinic Acid-photodynamic Therapy for Actinic NCT03596619	Shanghai Dermatology Hospital	N/A
Completed	5-ALA Patch-PDT of Actinic Keratosis on the Upper Extremities NCT03606122	photonamic GmbH & Co. KG	Phase 2
Completed	Microwave Therapy for Treatment of Precancerous Actinic Keratoses NCT03483935	University of Dundee	N/A
Completed	Nevus Doctor Clinical Decision Support for GPs NCT03246412	University Hospital of North Norway	N/A
Completed	Therapeutic Equivalence of Diclofenac Sodium Gel 3% vs Solaraze ® in the Treatment of Actinic Keratosis NCT03826550	Encube Ethicals Pvt. Ltd.	Phase 3
Recruiting	Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia NCT03906253	Wright State University	N/A
Completed	Daylight Photodynamic Therapy for Actinic Keratosis NCT03322293	University of California, San Francisco	Phase 1
Completed	Treatment of Actinic Keratosis With 5% KOH Solution NCT04024579	Infectopharm Arzneimittel GmbH	—
Completed	Validation of SHADE a Mobile Technology for Monitoring of Ultraviolet Exposure NCT03315286	Weill Medical College of Cornell University	N/A
Completed	Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects o NCT03279328	University of Arizona	Phase 4
Completed	A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp NCT03285477	Almirall, S.A.	Phase 3
Completed	PRO With Luxerm® in the Field Treatment of Thin and Non-hyperkeratotic Non-pigmented AK NCT03511326	Galderma R&D	Phase 4
Active Not Recruiting	Photodynamic Therapy Incubation Times for Actinic Keratosis NCT03066843	Northwestern University	N/A
Completed	Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients NCT04843553	Rhode Island Hospital	EARLY_Phase 1
Unknown	New Treatments for Actinic Keratoses of the Scalp NCT05456334	Helsinki University Central Hospital	N/A
Completed	Daylight-PDT With MAL for AK and Photodamaged Skin NCT02736760	University Hospital Regensburg	Phase 4
Withdrawn	Photo-therapy With a Topical Retinoid Versus Photo-therapy Alone for Actinic Keratoses NCT00756288	Northwestern University	N/A
Completed	Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy Wit NCT02622594	Dermatology, Laser & Vein Specialists of the Carolinas	Phase 4
Completed	Actinic Keratoses Treatment With Metvix® in Combination With Light NCT02373371	University Hospital, Limoges	Phase 3
Completed	Treatment of Actinic Keratoses (AK) on the Face NCT02411851	Icahn School of Medicine at Mount Sinai	Phase 1
Completed	A Clinical Trial Evaluating the Role of Systemic Antihistamine Therapy in the Reduction of Adverse Effects Ass NCT02451579	Goldman, Butterwick, Fitzpatrick and Groff	N/A
Completed	Daylight-mediated Photodynamic Therapy of Actinic Keratoses:Comparing 0.2%HAL With 16%MAL NCT02149342	Joint Authority for Päijät-Häme Social and Health Care	Phase 1 / Phase 2
Completed	A Comparison of White-light and Daylight Topical Methyl 5-aminolaevulinic Acid Photodynamic Therapy for Actini NCT02520700	St Vincent's University Hospital, Ireland	N/A
Completed	Phase 3b Study of Metvix NDL-PDT Versus Metvix c-PDT in Subjects With Actinic Keratoses NCT01821391	Galderma R&D	Phase 3
Completed	Effects of Topical Diclofenac on Tumor Metabolism NCT01935531	University Hospital Regensburg	Phase 4
Completed	Safety and Efficacy of Ingenol Mebutate 0.05% Gel When Used After Cryotherapy in the Hypertrophic Actinic Kera NCT02251652	Icahn School of Medicine at Mount Sinai	Phase 4
Completed	Continuous Quality Improvement (CQI) Pilot Study Evaluating the Utility of an Educational Video NCT02062853	University of California, Davis	N/A
Terminated	Imiquimod Versus Photodynamic Therapy of Actinic Keratoses in Organ Transplant Recipients NCT01538901	Medical University of Vienna	Phase 4
Completed	Intra-individual Comparison of Efficacy and Safety of Metvix® Natural Daylight Photodynamic Therapy Versus Con NCT01475071	Galderma R&D	Phase 3
Completed	A Bioequivalence Study With Clinical Endpoints Comparing Generic Imiquimod Cream, 3.75% and Zyclara™ (Imiquimo NCT01502020	Actavis Mid-Atlantic LLC	N/A
Terminated	Prevention of UV-induced Carcinogenic Skin Alterations in Immunosuppressed Solid Organ Transplanted Patients NCT01532453	Spirig Pharma Ltd.	Phase 3
Completed	Bioequivalence Study of Generic Fluorouracil 0.5% Cream and 0.5% Carac® and Placebo NCT01354717	Spear Pharmaceuticals	Phase 3
Completed	Photodynamic Therapy With Levulan® +/- Topical Retinoid Pre-Treatment In The Treatment Of Actinic Keratoses NCT01053000	Stewart, Roger H., M.D., P.A.	N/A
Completed	A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Ac NCT00942604	Peplin	Phase 3
Terminated	ALA-PDT Versus Vehicle PDT for Treatment of AK and Reduction of New NMSC in Solid Organ Transplant Recipients NCT00865878	DUSA Pharmaceuticals, Inc.	Phase 2
Completed	The Efficacy and Tolerability of Oleogel-S-10 in Patients With Actinic Keratoses NCT00786994	Birken AG	Phase 2
Completed	Topical Imiquimod Cream in Combination With Cryotherapy for the Treatment of Actinic Keratoses NCT00774787	Rigel Dermatology	Phase 4
Completed	A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Ac NCT00742391	Peplin	Phase 3
Completed	Carac & PDT Combination in the Treatment Of Actinic Keratoses NCT06712381	Skin Laser & Surgery Specialists	Phase 1 / Phase 2
Completed	A Randomized Multicenter Study of Daylight Mediated Photodynamic Therapy (PDT) NCT00711178	Bispebjerg Hospital	N/A
Completed	Bioequivalence of Generic Imiquimod Cream, 5% When Compared to Aldara™ (Imiquimod) Cream, 5% in the Treatment NCT00948428	Actavis Inc.	Phase 3
Completed	Follow-up Study to Evaluate Sustained Clearance Rates of Actinic Keratoses up to One Year NCT00668733	Graceway Pharmaceuticals, LLC	—
Completed	Safety and Effectiveness Study of Imiquimod Creams for Treatment of Actinic Keratoses (AKs) NCT00605176	Graceway Pharmaceuticals, LLC	Phase 3
Unknown	Phase II AK Study in Organ Transplant Patients NCT00829192	Clinuvel Pharmaceuticals Limited	Phase 2
Completed	Pharmacokinetic Study to Evaluate the Extent of Systemic Absorption of PEP005 NCT00544258	Peplin	Phase 1
Completed	A Photodynamic Therapy for Treatment of Actinic Keratoses NCT00558688	Northwestern University	N/A
Completed	A Study to Determine the Optimal Tolerated Regime and Safety of PEP005 Topical Gel NCT00427050	Peplin	Phase 2
Completed	Treatment of Actinic Keratoses With Photodynamic Therapy Using Sunlight Versus Red Light NCT00432224	Bispebjerg Hospital	N/A
Completed	A Study to Follow up Recurrence Rates of Actinic Keratoses One Year After Completion of Study 1487-IMIQ NCT00189254	MEDA Pharma GmbH & Co. KG	—
Completed	Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic Keratoses NCT00175643	University of British Columbia	Phase 3
Completed	An Open-Label 18-Month Safety Study of Fluorouracil Cream 0.5% for the Treatment of Actinic Keratoses NCT00377273	Sanofi	Phase 4