NCT03066843

Photodynamic Therapy Incubation Times for Actinic Keratosis

A Randomized Controlled Trial Evaluating 5-aminolevulinic Acid Photodynamic Therapy With Different Incubation Times for the Treatment of Actinic Keratosis

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Northwestern University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This is a randomized clinical trial evaluating blue light 5-aminolevulinic acid (ALA) photodynamic therapy with different incubation times for the treatment of actinic keratosis. Subjects who are interested in participating, currently living in the Chicago metropolitan area, and meet inclusion and exclusion criteria will be enrolled in the study. Subjects will be randomized to either 1) zero time ALA incubation or 2) 1 hour ALA incubation. Demographic and health data will be collected prior to treatment initiation. Three visits will be conducted: screening, treatment, and follow up visit at 8 weeks. This study is a pilot study designed to determine feasibility of this procedure.

Conditions

• Actinic Keratoses

Interventions

Type	Name	Description
DRUG	ALA (5-aminolevulinic acid)	ALA (5-aminolevulinic acid) will be applied to subjects' skin for either zero time incubation or one hour incubation
DEVICE	Blue light therapy	Subjects will be exposed to blue light

Timeline

• Start date: 2017-03-01
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2017-02-28
• Last updated: 2025-01-31

Locations

1 site across 1 country: United States