NCT04969419

Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo: A Case-control Study in the United Kingdom, 2009-2020

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 75,771 (actual)
• Sponsor: Momentum Data · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

This study examines melanoma and nonmelanoma skin cancer in people diagnosed with vitiligo compared to matched controls.

Detailed description

For the primary analysis, this study examines the risk of melanoma and nonmelanoma skin cancers: squamous cell carcinoma and basal cell carcinoma in people diagnosed with vitiligo. It also examines actinic keratoses. In secondary analysis, this study examines the prevalence of skin cancer in people diagnosed with vitiligo compared to matched controls. This study also examines whether the susceptibility to melanoma and nonmelanoma skin cancer may vary between different patient subgroups, e.g. ethnicity, those who undergo phototherapy or treatment with the new targeted biologic immunosuppressive therapies.

Conditions

• Vitiligo
• Melanoma (Skin)
• Nonmelanoma Skin Cancer
• Squamous Cell Carcinoma
• Basal Cell Carcinoma
• Actinic Keratoses

Interventions

Type	Name	Description
OTHER	Exposure of skin cancer of interest	Melanoma and nonmelanoma skin cancers: squamous cell carcinoma, basal cell carcinoma and actinic keratoses.

Timeline

• Start date: 2021-06-18
• Primary completion: 2022-03-31
• Completion: 2023-04-04
• First posted: 2021-07-20
• Last updated: 2025-01-14
• Results posted: 2025-01-14

Locations

1 site across 1 country: United Kingdom