NCT07464106

Evaluation of the Impact of Interventional Treatments for Symptomatic, Severe Tricuspid Valve Insufficiency on Renal Integrity and Function, as Well as on Physical Function and Activity in Older Adults.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Robert Bosch Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The hypothesis is that renal function will improve following tricuspid valve intervention. A reduction in renal biomarkers is also expected. Furthermore, based on previous assessments, it is anticipated that there will be an improvement in volume status (reduced edema), symptom burden, and physical capacity in patients. Additionally, the study will assess the impact of the intervention on functional parameters such as motor capacity, physical activity, performance of activities of daily living, and ultimately, participation and quality of life.

Conditions

• Tricuspid Regurgitation
• Tricuspid Valve Insufficiency
• Cardio-Renal Syndrome
• Frailty

Interventions

Type	Name	Description
PROCEDURE	Transcatheter edge-to-edge repair (TEER)	Routine intervention, observational

Timeline

• Start date: 2025-02-01
• Primary completion: 2026-12-01
• Completion: 2027-12-01
• First posted: 2026-03-11
• Last updated: 2026-03-11

Locations

1 site across 1 country: Germany