Trials / Terminated
TerminatedNCT07254988
Gut Peptides and Bone Remodeling in Children With Neuromuscular Disorders
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 3 (actual)
- Sponsor
- University of Copenhagen · Academic / Other
- Sex
- All
- Age
- 10 Years – 17 Years
- Healthy volunteers
- Not accepted
Summary
Both GIP and GLP-2 reduce bone resorption (measured as CTX) in healthy adult individuals. In this study, we will investigate whether GIP and GLP-2 reduce CTX in children with spinal muscular atrophy, duchenne muscular dystrophy, or cerebral palsy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Meal test | Ingestion of an oral liquid meal (nutridrink), 3.3 mL/kg body weight. |
| OTHER | GIP + GLP-2 | Subcutaneous GIP + GLP-2 injection (1 mL containing 100 microgram GIP + 1 mL containing 400 microgram GLP-2). |
| OTHER | Placebo | Subcutaneous saline injection (2 mL isotonic saline). |
Timeline
- Start date
- 2023-03-24
- Primary completion
- 2025-12-01
- Completion
- 2025-12-01
- First posted
- 2025-11-28
- Last updated
- 2026-04-16
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT07254988. Inclusion in this directory is not an endorsement.