NCT07195110

Prevalence of Periodontitis in Egyptian Multiple Sclerosis Patients.

Prevalence of Periodontal Disease Among Egyptian Patients With Multiple Sclerosis S: A Cross Sectional Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 293 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to explore the association between multiple sclerosis and periodontal disease in a sample of Egyptian population The main question it aims to answer is: • Is there an association between MS and periodontal disease Participants already diagnosed with multiple sclerosis. A conventional oral examination will be held on a dental unit, filling charts and patients' acceptance to participate in the survey.

Detailed description

Periodontal disease is a chronic inflammatory condition leading to progressive destruction of the supporting structures of the teeth. Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that may share common inflammatory pathways with periodontal disease. Recent evidence suggests that systemic inflammation may influence the severity and progression of both conditions. This study will recruit participants already diagnosed with MS and assess their periodontal status using standard clinical parameters, including clinical attachment loss (CAL), probing pocket depth, and bleeding on probing measured at six sites per tooth using a periodontal probe. Data will be collected through a conventional oral examination in a dental unit, and results will be compared to evaluate the prevalence and potential association between MS and periodontal disease within this population.

Conditions

• Multiple Sclerosis (MS)
• Periodontal Diseases

Timeline

• Start date: 2025-09-18
• Primary completion: 2026-02-01
• Completion: 2026-03-16
• First posted: 2025-09-26
• Last updated: 2026-03-18

Locations

1 site across 1 country: Egypt