Trials / Recruiting
RecruitingNCT07130760
Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
Is Intraligamentary Injection the Anesthesia of Choice for Symptomatic Irreversible Pulpitis in Mandibular Molars? A Multicenter Randomized Comparative Trial.
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 52 (estimated)
- Sponsor
- Aula Dental Avanzada · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars. The goal is to determine which technique provides better pain control during endodontic treatment.
Detailed description
Symptomatic irreversible pulpitis in mandibular molars presents a clinical challenge due to the difficulty in achieving profound anesthesia. This prospective, randomized, controlled clinical trial evaluates two anesthetic techniques-intraligamentary injection (ILA) versus inferior alveolar nerve block (IANB)-to compare their efficacy in eliminating pain during endodontic access. Patients will be enrolled from multiple dental centers following standardized inclusion and exclusion criteria. Pain will be assessed using validated scales. Statistical analysis will be conducted to determine significant differences in anesthetic success between groups.
Conditions
- Symptomatic Irreversible Pulpitis (SIP)
- Dental Pain
- Inferior Alveolar Nerve Block Failure
- Local Anesthesia
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Intraligamentary Injection | Intraligamentary local anesthesia will be administered using a standard dental syringe with 2% lidocaine and 1:100,000 epinephrine. |
| PROCEDURE | Inferior Alveolar Nerve Block | Inferior alveolar nerve block will be performed with 2% lidocaine and 1:100,000 epinephrine using the conventional technique. |
Timeline
- Start date
- 2025-06-20
- Primary completion
- 2027-06-01
- Completion
- 2027-07-01
- First posted
- 2025-08-19
- Last updated
- 2025-08-19
Locations
2 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT07130760. Inclusion in this directory is not an endorsement.