NCT06955286

Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Qifu Li · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the incidence of adrenal insufficiency after surgery in Primary aldosteronism (PA) patients concurrent with or without autonomous cortisol secretion (ACS).

Detailed description

This study is a prospective, single-center research. Primary aldosteronism patients concurrent with or without autonomous cortisol secretion who underwent adrenalectomy and completed the adrenocorticotropic hormone (ACTH) stimulation test will be included. To evaluate the incidence of adrenal insufficiency after surgery in these patients.

Conditions

• Primary Aldosteronism
• Autonomous Cortisol Secretion
• Adrenal Insufficiency

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	complete ACTH stimulation test the day after surgery	patients complete ACTH stimulation test on the one day after surgery

Timeline

• Start date: 2025-01-02
• Primary completion: 2027-12-31
• Completion: 2028-12-31
• First posted: 2025-05-02
• Last updated: 2025-08-01

Locations

1 site across 1 country: China