NCT06843213

Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention

Teaching Health Promotion and Resilience in Varied Environments: a Peer-led Intervention Following Hospital Discharge

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 390 (estimated)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to develop an acceptable, feasible, and effective peer-led bundle of health resilience and promotion services to be delivered in the hospital setting, called the THRIVE intervention. The main question it aims to answer is: Will participants receiving the THRIVE intervention have a reduced risk of self-reported non-fatal overdoses OR skin/soft tissue infections compared to participants receiving enhanced usual care? Researchers will compare the THRIVE model to enhanced usual care to see if the THRIVE model helps participants reduce their number of self-reported non-fatal overdoses OR skin/soft tissue infections. Intervention participants will: * Receive one in-person session from a peer support specialist while in the hospital * Receive weekly text messages from the peer support specialist for a 12-week period * Receive monthly, multiple-choice assessments via text message at Month 1, 2, 3, 4, 5, and 6 * Complete a baseline, 3-month, and 6-month assessment with Research Assistants Enhanced usual care participants will: * Receive a handout with health resilience education and resources in their local area * Receive monthly, multiple-choice assessments via text message at Month 1, 2, 3, 4, 5, and 6 * Complete a baseline, 3-month, and 6-month assessment with Research Assistants

Conditions

• Opioid Use Disorder
• Harm Reduction
• Health Promotion

Interventions

Type	Name	Description
BEHAVIORAL	Peer Intervention	Participants will receive one peer-led, in-person session boosted by weekly text messages over a 12-week period.
OTHER	Enhanced Usual Care	Participants will receive a handout that includes health resilience education and resources in their local area as part of enhanced usual care.

Timeline

• Start date: 2025-02-18
• Primary completion: 2028-04-01
• Completion: 2028-08-01
• First posted: 2025-02-24
• Last updated: 2026-02-27

Locations

3 sites across 1 country: United States