NCT06711341

Comparing Exercise Programs for Managing Knee Osteoarthritis

Investigating The Most Effective Exercise Modality in Knee Osteoarthritis; A RCT

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 69 (actual)
• Sponsor: Uludag University · Academic / Other
• Sex: All
• Age: 45 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to assess and compare the effectiveness of three different exercise modalities-whole-body vibration exercise, progressive resistance exercise, and home-based exercise -in improving quadriceps isometric muscle strength, physical function, balance, knee pain, osteoarthritis symptoms, and overall quality of life in individuals with knee osteoarthritis. The main questions it aims to answer are: * How do WBV, PRE, and home-based exercise compare in improving quadriceps strength in people with knee osteoarthritis? * Which exercise modality leads to the greatest improvements in physical function, balance, knee pain, and quality of life? Researchers will compare the three exercise regimens to determine which is most effective for improving knee function and relieving osteoarthritis symptoms. Participants will: * Engage in whole-body vibration exercise, progressive resistance exercise, or home-based exercise for 3 weeks. * Undergo assessments before and at the end of the exercise program, including tests for physical function and balance (Timed Up and Go Test, 5x Sit to Stand Test) and questionnaires to evaluate knee osteoarthritis symptoms (WOMAC), quality of life (SF-36), and self-reported knee pain (Numeric Rating Scale).

Conditions

• Knee OA
• Osteoarthritis
• Osteoarthritis (OA) of the Knee

Interventions

Type	Name	Description
DEVICE	Whole-body Vibration (WBV) Training	Participants use the "Compex Winplate," designed specifically for vibration training. The device is set with a frequency of 30 Hz and an amplitude of 4 mm. Participants perform a total of 5 exercises consisting of static and dynamic squat exercises, with a 30-second rest period between sets and between different exercises. The exercises and progression over the weeks are as follows: Week 1: * Static squat with knees flexed at 30° - 2 sets of 30 seconds each * Dynamic squat with knees flexed between 0-60° - 2 sets of 30 seconds each * Fingertip-to-sole partial dynamic squat with knees flexed at 30° - 2 sets of 30 seconds each * Consecutive weight transfer with knees flexed at 45° - 2 sets of 30 seconds each * Single leg static squat with knees flexed at 30° - 30 seconds per leg Subsequent Weeks: The duration of each set increases by 10 seconds each week. Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises.
BEHAVIORAL	Progressive Resistance Exercise (PRE)	Training Duration: Participants undergo approximately 15-20 minute training sessions, 3 days per week for 3 weeks. Exercise Regimen: The training focuses on strengthening the quadriceps muscles using ankle weights. The load is determined using the DeLorme principle: * At the beginning of each week, the 10-repetition maximum (10RM) is measured. * During that week, participants perform their training sets as follows: * First set: 50% of 10RM * Second set: 75% of 10RM * Final set: 100% of 10RM Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises.
BEHAVIORAL	Home-Based Exercise	Protocol: Participants receive a printed document with instructions for home exercises and are instructed on how to perform the exercises. Training Duration: Sessions are conducted three days per week for 3 weeks. Exercise Regimen: The exercises include: * Bilateral Quadriceps Isometric Exercise: Participants lie on their backs with a roll below each knee, pressing for 10-second holds, totaling 20 repetitions. * Knee Extensions: Participants performed knee extensions while seated, holding each extension for 5 seconds, completing 10 repetitions per leg. * Knee Range of Motion (ROM) Exercises: Participants lie face down and alternately bend their knees, completing 10 repetitions. Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises

Timeline

• Start date: 2023-08-01
• Primary completion: 2024-05-01
• Completion: 2024-08-01
• First posted: 2024-12-02
• Last updated: 2024-12-02

Locations

1 site across 1 country: Turkey (Türkiye)