NCT06510608

Periodontal Disease and Salivary Mitofusin Levels

Evaluation of the Roles of Salivary Mitofusin-1 and Mitofusin-2 Levels in Periodontal Disease

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 81 (estimated)
• Sponsor: Erzincan University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this observational study is to find out whether there is a level difference in salivary mitofusin-1 and mitofusin-2 levels due to changes in periodontal status. The main question it aims to answer is: * Do salivary mitofusin-1 and mitofusin-2 levels of periodontitis patients differ from healthy patients? * Could salivary mitofusin-1 and mitofusin-2 levels be biomarkers for periodontal disease? Biochemical analysis will be performed on saliva samples taken at once from gingivitis or periodontitis patients and healthy individuals who apply to the periodontology clinic, at the initial stage of the treatment. There is no ongoing monitoring or second sampling.

Conditions

• Periodontitis
• Periodontal Diseases
• Gingivitis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Biochemical analysis of saliva sample	It is the examination of saliva samples taken with biochemical methods. In this way, the substances in its content and the concentration of cytokines are analyzed.

Timeline

• Start date: 2024-07-25
• Primary completion: 2024-08-25
• Completion: 2024-09-25
• First posted: 2024-07-19
• Last updated: 2024-07-19