NCT06470204

Dexamethasone for iPACK Block With ACB in Total Knee Arthroplasty

Infiltration Between the Popliteal Artery and Capsule of the Knee Block With Adductor Canal Block With Ropivacaine vs Ropivacaine and Dexamethasone in Total Knee Arthroplasty: A Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Poznan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 65 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Effect of adding Dexamethasone to Infiltration between the Popliteal Artery and Capsule of the Knee Block with ACB in Patients undergoing Total Knee Arthroplasty

Detailed description

Knee arthroplasty is one of the most common orthopaedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prostheses. Regional anaesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.

Conditions

• Knee Osteoarthritis
• Knee Pain Chronic
• Knee Arthritis

Interventions

Type	Name	Description
DRUG	Ropivacaine	Ultrasound-guided iPACK block + ACB - 2 x (20ml 0,2% ropivacaine + 2ml 0.9% NaCl)
DRUG	Ropivacaine+Dexamethasone	Ultrasound-guided iPACK block + ACB - 2 x (20ml 0,2% ropivacaine + 2mg Dexamethasone)

Timeline

• Start date: 2024-08-13
• Primary completion: 2025-01-31
• Completion: 2025-03-30
• First posted: 2024-06-24
• Last updated: 2025-07-23

Locations

1 site across 1 country: Poland