NCT06297044

Neural and Cognitive Correlates of Pragmatic Abilities

Neural and Cognitive Correlates of Pragmatic Communication Abilities

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 324 (estimated)
• Sponsor: IRCCS San Camillo, Venezia, Italy · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively. Disorders in the pragmatics of language are prevalent in various clinical populations. They are a cause of social withdrawal and worse quality of life, both for patients directly affected and for their family members. Despite this, this type of disorder is rarely considered in neuropsychological assessment and rehabilitation. This study's objective is to characterize pragmatic deficits in various neurological populations, allowing for the most accurate diagnosis possible and leading to the planning of personalized and effective Rehabilitation Plans.

Detailed description

To delineate the pragmatic deficit profile for each pathology group, eligible participants will undergo a neuropsychological assessment, subdivided into as many sessions as per the participant's availability and tolerance. Assessment tools will include: * APACS (A test for the Assessment of Pragmatic Abilities and Cognitive Substrates; Arcara and Bambini, 2016) * SET (Story-based Empathy Task, Dodich et al., 2015) * COAST (Communication Outcome After Stroke, Bambini et al., 2016) * PWB (Psychological Well-Being scales, Sirigatti et al., 2009) * other neuropsychological assessment tools depending on the participant's pathology and routinely used in the clinical practice within the Institution. Resulting test scores will be statistically analyze to provide pragmatic and cognitive profiles for each pathology.

Conditions

• Right Hemispheric Stroke
• Left Hemispheric Stroke
• Traumatic Brain Injury
• Right Hemispheric Brain Tumor
• Left Hemispheric Brain Tumor
• Mild Cognitive Impairment
• Healthy

Interventions

Type	Name	Description
OTHER	Neuropsychological assessment	* APACS assessing various aspects of pragmatic communication abilities; * SET assessing cognitive and emotional theory of mind; * COAST assessing functional communication impairments in daily activities and their impact on the quality of life after the illness onset; * PWB assessing the individual's perceived quality of life and psychological well-being; * other neuropsychological assessment tools depending on the participant's pathology and routinely used in the clinical practice within the Institution.

Timeline

• Start date: 2018-03-29
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2024-03-06
• Last updated: 2024-03-06

Locations

1 site across 1 country: Italy