NCT06291597

Vaping Adverse Lung and Heart Events Cohort

VapALERT: A Prospective, Exploratory and Adaptive Cohort Study to Identify Symptomatic and Asymptomatic Pulmonary and Cardiovascular Effects of Vaping

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 250 (estimated)
• Sponsor: Laval University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This prospective study assesses the pulmonary and cardiovascular effets of vaping in adult electronic cigarette users with biannual visits and a 5-year follow-up.

Detailed description

Daily vaping device users will be recruited in the Quebec City metropolitan area. Subjects will be asked to perform pulmonary function tests (spirometry, oscillometry, plethysmography, methacholine provocation) every 6 months for a 5-year follow up. Subjects will also answer a questionnaire assessing their vaping, tobacco and cannabis smoking habits, as well as their perceived respiratory symptoms. Blood draws and sputum inductions will be performed for cell counts and to measure inflammation markers.

Conditions

• Vaping
• Electronic Cigarette Use

Interventions

Type	Name	Description
OTHER	Vaping	Participants use their vaping products at their own discretion and their intake is monitored via questionnaires.

Timeline

• Start date: 2021-10-14
• Primary completion: 2031-12-01
• Completion: 2032-06-01
• First posted: 2024-03-04
• Last updated: 2024-03-04

Locations

1 site across 1 country: Canada