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Active Not RecruitingNCT06209567

A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors

An Investigator-Initiated Study to Evaluate PSMA Expression in Patients With High-Grade Gliomas or Brain Metastases With 68Ga-PSMA-11 PET

Status
Active Not Recruiting
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
11 (actual)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to find out whether 68Ga-PSMA-11 PET/CT is effective in assessing tumor uptake (tumor activity seen in cancerous tissue) in participants with high-grade glioma/HGG or brain metastases.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TEST68Ga-PSMA-11 PET ScansParticipants will be injected intravenously with 68Ga-PSMA-11 via intravenous catheter. PET scans will first be interpreted without information on the results of other imaging modalities. Following the blinded read of the 68Ga-PSMA-11 PET scans, all recorded findings will be correlated with the results of CE CT and MR studies and 18F-FDG PET/CT or PET/MR performed as part of standard clinical care.

Timeline

Start date
2024-01-05
Primary completion
2027-01-05
Completion
2027-01-05
First posted
2024-01-17
Last updated
2025-12-03

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06209567. Inclusion in this directory is not an endorsement.