Trials / Completed
CompletedNCT06145685
Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- October 6 University · Academic / Other
- Sex
- All
- Age
- 20 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study is to evaluate the effect of smoking cessation on inflammatory markers following non-surgical treatment of periodontal disease. This is to assess the period of smoking abstinence needed before any periodontal surgery in order to reverse the negative effects of the reported increased levels of inflammatory markers (IL-1β and PGE2 in this study) associated with smoking on the healing and the periodontium.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Minimally invasive non-surgical periodontal therapy | Minimally invasive non-surgical periodontal therapy |
| PROCEDURE | Conventional non-surgical periodontal therapy | Conventional non-surgical periodontal therapy |
Timeline
- Start date
- 2021-01-01
- Primary completion
- 2022-02-28
- Completion
- 2022-02-28
- First posted
- 2023-11-24
- Last updated
- 2023-11-24
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT06145685. Inclusion in this directory is not an endorsement.