Trials / Active Not Recruiting
Active Not RecruitingNCT05956834
A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- Massachusetts General Hospital · Academic / Other
- Sex
- All
- Age
- 40 Years – 89 Years
- Healthy volunteers
- Not accepted
Summary
The primary objective of this study is to enroll an observational cohort of approximately 60 patients with PSP over the course of 24 months using a multicenter study design and to follow each of them for 12 months. The secondary objective of this study is to develop a robust solution for multi-modal remote monitoring of motor symptoms and function in PSP that can be applied to other Frontotemporal lobar degeneration (FTLD) syndromes.
Detailed description
The goal of this project is to develop a robust multi-modal platform for remote monitoring of motor symptoms and cognitive function in FTLD syndromes using wearable sensors and mobile health technology to assess speech, motor, and cognitive functions. The solution will be validated in Progressive Supranuclear Palsy (PSP) by collecting longitudinal data from 60 PSP individuals with PSP. Enrollment will take place over a period of 24 months, though each participant will only be followed for 12 months for data collection. The participants will consist of adult volunteers from two leading CurePSP Centers of Care located at the Atypical Parkinsonism Center at Johns Hopkins Hospital in Baltimore, MD and Massachusetts General Hospital (MGH) in Boston, MA.
Conditions
- PSP
- CBD
- Progressive Supranuclear Palsy
- FTD
- Corticobasal Degeneration
- Frontotemporal Dementia
- Frontotemporal Lobar Degeneration
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | PAMSys | Wearable accelerometer and gyroscope for measuring movement |
| DEVICE | LEGSys | Wearable accelerometer and gyroscope for measuring movement |
Timeline
- Start date
- 2023-07-28
- Primary completion
- 2026-06-30
- Completion
- 2027-12-30
- First posted
- 2023-07-21
- Last updated
- 2026-01-21
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT05956834. Inclusion in this directory is not an endorsement.