Clinical Trials Directory

Trials / Unknown

UnknownNCT05865496

A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps

A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase II Clinical Study to Evaluate the Efficacy and Safety of 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
90 (estimated)
Sponsor
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the effect and safety of 611 in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP).

Detailed description

The main purpose is to evaluate the effect of 611 on a background of mometasone furoate nasal spray (MFNS) in reducing endoscopic nasal polyp score (NPS) and nasal congestion/obstruction score (NCS) severity in eligible patients with CRSwNP whose disease remains inadequately controlled despite daily treatment with intranasal corticosteroid (INCS) therapy in comparison to placebo.

Conditions

Interventions

TypeNameDescription
DRUG611611 subcutaneous (SC) injection.
DRUGPlaceboPlacebo subcutaneous (SC) injection.

Timeline

Start date
2023-06-30
Primary completion
2024-05-31
Completion
2024-07-31
First posted
2023-05-19
Last updated
2024-01-12

Locations

4 sites across 1 country: China

Source: ClinicalTrials.gov record NCT05865496. Inclusion in this directory is not an endorsement.