Clinical Trials Directory

Trials / Completed

CompletedNCT05777863

The Effects of a Multidomain Lifestyle Intervention on Brain Functioning and Its Relation With Immunometabolic Markers in Ageing

The Effects of a Multidomain Lifestyle Intervention on Brain Functioning and Its Relation With Immunometabolic Markers in Ageing: the HELI Study

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
102 (actual)
Sponsor
Donders Centre for Cognitive Neuroimaging · Academic / Other
Sex
All
Age
60 Years – 75 Years
Healthy volunteers
Not accepted

Summary

HELI is a multicenter, randomised controlled trial in two Dutch research centres (Donders Centre for Cognitive Neuroimaging, Nijmegen, and the department of Human Nutrition \& Health at Wageningen University) among 104 older adults aged 60-75 years who are at risk for cognitive decline with an intervention duration of 26 weeks (roughly 6 months). Participants are randomized in a 1:1 ratio to a multidomain lifestyle intervention characterized by group-sessions and guidance (high-intensity intervention group) versus online access to general lifestyle-related health information in the form of biweekly leaflets (low-intensity intervention group).

Conditions

Interventions

TypeNameDescription
BEHAVIORALMultidomain lifestyle interventionA multidomain lifestyle intervention including the following lifestyle domains: (1) diet, (2) physical activity, (3) sleep, (4) stress/mindfulness, and (5) cognitive training.

Timeline

Start date
2022-05-10
Primary completion
2024-05-23
Completion
2024-05-23
First posted
2023-03-21
Last updated
2024-06-21

Locations

2 sites across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT05777863. Inclusion in this directory is not an endorsement.