NCT05678049

Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Iuliu Hatieganu University of Medicine and Pharmacy · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes. For patients with liquid under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physician. The investigators want to use this liquid for Microscopic and Spectrophotometric evaluation.

Conditions

• Osteoarthritis, Knee
• Knee Arthritis
• Gout Arthritis
• Microcrystal Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Synovial fluid analysis	For patients with knee under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physicians. After making the evacuation we will want to use this liquid for Microscopic and Spectrophotometric evaluation

Timeline

• Start date: 2023-01-15
• Primary completion: 2023-12-15
• Completion: 2024-12-15
• First posted: 2023-01-10
• Last updated: 2023-01-10