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Active Not RecruitingNCT04795934

Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repair

Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repair Combined With Transoral Incisionless Fundoplication Versus Laparoscopic Nissen Fundoplication for Treatment of Gastroesophageal Reflux Disease in Patients Requiring Hiatal Hernia Repair

Status
Active Not Recruiting
Phase
N/A
Study type
Interventional
Enrollment
142 (estimated)
Sponsor
Mayo Clinic · Academic / Other
Sex
All
Age
22 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This single-blind randomized control study will follow 142 subjects across 7 sites randomized on a 1:1 ratio to compare treatment efficacy and safety between TIF and LNF in GERD patients with hiatal hernia undergoing hernia repair.

Conditions

Interventions

TypeNameDescription
PROCEDURELAPAROSCOPIC PARAESOPHAGEAL HIATAL HERNIA REPAIR COMBINED WITH TRANSORAL INCISIONLESS FUNDOPLICATIONLAPAROSCOPIC PARAESOPHAGEAL HIATAL HERNIA REPAIR COMBINED WITH TRANSORAL INCISIONLESS FUNDOPLICATION VERSUS LAPAROSCOPIC NISSEN FUNDOPLICATION

Timeline

Start date
2021-01-26
Primary completion
2025-07-31
Completion
2030-01-01
First posted
2021-03-12
Last updated
2025-08-19

Locations

7 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT04795934. Inclusion in this directory is not an endorsement.

Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repair (NCT04795934) · Clinical Trials Directory