| Not Yet Recruiting | Image-Guided Herniorrhaphy Study NCT07267494 | University of California, Davis | N/A |
| Recruiting | Evaluating Clinical Hiatal Hernia Outcomes Using OviTex® NCT07070115 | Tela Bio Inc | N/A |
| Completed | Laparoscopic Hiatal Hernia Repair With Mesh Cruroplasty NCT07491003 | Zagazig University | N/A |
| Not Yet Recruiting | Comparative 3-year Study of Nissen-sleeve vs. Sleeve Plus Cruroplasty in Obese Patients With Hiatal Hernia NCT06835790 | Elsan | N/A |
| Recruiting | Nissen Versus Dor Hiatal Hernia Repair NCT06725433 | Kuopio University Hospital | N/A |
| Recruiting | Laparoscopic Toupet's Fundoplication: Is it Proper Solution of Radiological Negative, Endoscopically Positive NCT06884800 | Minia University | N/A |
| Recruiting | Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair NCT06444347 | Weill Medical College of Cornell University | N/A |
| Completed | Safety and Feasibility of Liver Retraction With the Levita Magnetic Surgical System: Extended Magnetic Grasper NCT06432088 | Levita Magnetics | N/A |
| Not Yet Recruiting | A Prospective Randomised Multi - Center Trial on the Repair of Large Hiatal Hernias: Absorbable Mesh vs. Pledg NCT04591860 | Paracelsus Medical University | N/A |
| Recruiting | Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia NCT05953428 | Endeavor Health | N/A |
| Unknown | Treatment of Reflux With Sleeve Gastrectomy NCT06170060 | Yusuf Emre ALTUNDAL | N/A |
| Unknown | Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CA NCT05710913 | Dr. Med Anas Taha | — |
| Completed | Hiatal Hernia and Pulmonary Involvement NCT05716022 | University of Virginia | — |
| Unknown | Can EndoFLIP Improve Quality of Life Before and After Fundoplication? NCT06159972 | Dr. Wiley Chung | N/A |
| Recruiting | Sutures Versus Polyglactin Mesh in Hiatal Hernia Repair NCT05201508 | Oulu University Hospital | N/A |
| Completed | Long-term Follow-up After Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing NCT05069493 | Karolinska University Hospital | — |
| Unknown | Pain Relief After Hiatal Hernia Repair Surgery NCT04936711 | Norton Thoracic Institute | Phase 4 |
| Active Not Recruiting | Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repa NCT04795934 | Mayo Clinic | N/A |
| Terminated | LINX Reflux Management System or Fundoplication Clinical Study in Patients With Hiatal Hernia >3 cm NCT04695171 | Foregut Research Foundation | — |
| Completed | Incentive Spirometry and Upper Abdominal Laparoscopic Surgery NCT04716166 | Riphah International University | N/A |
| Active Not Recruiting | Esophagogastric Junction Distensibility During Hiatal Hernia Repair NCT04450628 | Wake Forest University Health Sciences | N/A |
| Completed | Laparoscopic Total Left-sided Surgical Approach Versus Traditional Bilateral Surgical Approach for Hiatal Hern NCT06828627 | Beijing Friendship Hospital | N/A |
| Completed | SurgiMend Mesh at the Hiatus NCT04282720 | Kettering Health Network | N/A |
| Unknown | Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese Patients NCT03776669 | National Taiwan University Hospital | N/A |
| Completed | Complications of Laparoscopic Hiatal Hernia Repair Complicated by Gastroesophageal Reflux Disease Using the ER NCT07138235 | Osh State University | — |
| Unknown | Registry of Outcomes From AntiReflux Surgery NCT02923362 | The Heartburn Foundation | — |
| Completed | Miromatrix Biological Mesh for Hiatal Hernia Repair NCT02436681 | Miromatrix Medical Inc. | N/A |
| Unknown | Biologic Versus Synthetic Mesh for Treatment of Paraesophageal Hernia NCT02242526 | Stony Brook University | Phase 4 |
| Unknown | Usage of Biological Patch Versus Plastic in the Laparoscopic Repair of Hiatal Hernias NCT02328248 | Xijing Hospital of Digestive Diseases | Phase 2 / Phase 3 |
| Completed | Approach to Hiatal Hernia Repair Based on Collagen Study NCT04152798 | Grubnik Volodymyr | N/A |
| Completed | Long-term Outcome of Laparoscopic Hiatal Hernia Repair With or Without Alloderm Mesh at a University Hospital NCT01776827 | University of Nebraska | — |
| Completed | Use of Strattice Mesh in Paraesophageal Hernia Surgery NCT01678157 | University of Nebraska | — |
| Completed | Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT Study NCT01136980 | EndoGastric Solutions | N/A |
| Completed | Transoral Incisionless Fundoplication (TIF) Registry Study for Treatment of Gastroesophageal Reflux Disease (G NCT01118585 | EndoGastric Solutions | N/A |
| Completed | Veritas Laparoscopic Paraesophageal Hiatal Hernia (PEH) Repair Pilot Trial NCT01195545 | University of Washington | N/A |
| Completed | Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD NCT01110811 | EndoGastric Solutions | N/A |
| Unknown | Study of Paraesophageal Hernia Repair With Small Intestine Submucosa NCT00786084 | University of Washington | — |
| Completed | The Biologic Basis of Hernia Formation NCT01099033 | Washington University School of Medicine | — |
| Completed | Necessity of Esophageal Dissection During Laparoscopic Fundoplication NCT00287612 | Children's Mercy Hospital Kansas City | N/A |
| Completed | Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing NCT03730233 | Karolinska Institutet | N/A |
| Completed | Foreshortened Esophagus and Its Surgical Therapy NCT00507377 | University of Bologna | — |
| Unknown | Immunologic Factors in Reflux Esophagitis and Barrett's Esophagus NCT00155805 | National Taiwan University Hospital | — |
| Completed | Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD) NCT00872755 | G. Hatzikosta General Hospital | Phase 4 |
| Recruiting | Esophageal Cancer Risk Registry NCT00260585 | University of Pittsburgh | — |