NCT06725433

Nissen Versus Dor Hiatal Hernia Repair

NiDor-study: a Randomized Controlled Trial Comparing Nissen and Dor Fundoplication in Hiatal Hernia Repair

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Kuopio University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hiatal hernia can present with a wide range of symptoms. An usual surgical repair technique usually includes Nissen fundoplication, while other procedures are less frequently employed. However, recurrence and reoperation rates remain high. This randomized controlled trial aims to compare the efficacy of Nissen and Dor fundoplication in preventing hiatal hernia recurrence and reducing the risk of reoperation Participants undergoing minimally invasive hiatal hernia repair will be randomly assigned to either Nissen or Dor fundoplication. Postoperatively at 12 months, anatomical recurrence rates based on computed tomography scans and symptomatic recurrence rates, anti-reflux medication use, GERD-related quality of life, and dysphagia symptoms will be assessed. A subsequent long-term follow-up study will conducted afterwards utilizing national registry data to evaluate reoperation rates and anti-reflux medication use

Conditions

• Hiatal Hernia
• Paraesophageal Hernia
• Recurrence

Interventions

Type	Name	Description
PROCEDURE	Nissen fundoplication	Hiatal hernia repair and Nissen fundoplication
PROCEDURE	Dor fundoplication	Hiatal hernia repair and Dor fundoplication

Timeline

• Start date: 2025-02-07
• Primary completion: 2030-01-30
• Completion: 2030-01-30
• First posted: 2024-12-10
• Last updated: 2025-02-19

Locations

1 site across 1 country: Finland