NCT04705610

Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography

EYE-SEP : Study of Social Cognition in Patients With Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Association de Recherche Bibliographique pour les Neurosciences · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study aims to: * analyze prospectively the prevalence of subclinical oculomotor disorders (OMDs) in different phenotypes of Multiple Sclerosis (MS) and to study correlations with brain MRI T2 data. * highlight link between modification of visual exploration strategies to decode emotions, and social behavioral disorders, in patients with demyelinating disease, from early to clinically definite stages.

Conditions

• Multiple Sclerosis (MS)
• Multiple Sclerosis (MS) Relapsing Remitting
• Multiple Sclerosis (MS) Primary Progressive
• Multiple Sclerosis (MS) Secondary Progressive
• Radiologically Isolated Syndrome
• Clinically Isolated Syndrome
• Healthy

Interventions

Type	Name	Description
OTHER	Video-oculography / Social cognition tasks / Neuropsychological evaluations	* Recording of eye movements with a video-oculography device during oculomotor paradigms (Fixations, horizontal and vertical reflex saccades, horizontal and vertical smooth pursuit, anti-saccades) * Recording of eye gaze with a video-oculography device during emotions recognition tasks (Reading the Mind in the Eyes test (Baron-Cohen 2001); Ekman Faces task (1976)) * Neurological evaluation * Neuropsychological evaluations * Social cognitions tasks * Behaviour assessment

Timeline

• Start date: 2017-05-23
• Primary completion: 2019-06-26
• Completion: 2019-06-26
• First posted: 2021-01-12
• Last updated: 2021-01-22

Locations

1 site across 1 country: Monaco