NCT04635657

Cognitive Status After Removal of Skull Base Meningioma

Pre and Post-Operative Cognitive Status in Patients Undergoing Surgery for Resection of Meningioma Associated With the Frontal and Temporal Lobes

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Ohio State University · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: —

Summary

The purpose of this prospectively enrolling trial is to assess long-term cognitive outcomes of patients undergoing surgery for resection of a meningioma associated with the frontal and temporal lobes.

Detailed description

This study will look at patients who are undergoing resection of a skull based meningioma, located in the frontal or temporal lobe, via craniotomy or via endoscopic endonasal approach. The study will compare cognitive function at baseline, at six weeks postoperatively and at one year postoperatively. The cognitive testing being done at baseline will be a clinical care set of assessments done by the speech language pathology team and will include the RBANS tests, the MoCA, PROMIS-29, and NeuroQOL-Cognitive Functions.

Conditions

• Meningioma
• Skull Base Meningioma
• Frontal Meningioma
• Temporal Meningioma
• Cognitive Impairment
• Cognitive Decline
• Post-Surgical Cognition

Interventions

Type	Name	Description
OTHER	Long-term Cognitive testing	These patients will undergo their standard of care cognitive testing at baseline, six weeks post-operatively and one year post-operatively.

Timeline

• Start date: 2019-12-10
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2020-11-19
• Last updated: 2023-10-24

Locations

1 site across 1 country: United States