Trials / Completed
CompletedNCT04600323
Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 34 (actual)
- Sponsor
- University of Colorado, Denver · Academic / Other
- Sex
- All
- Age
- 50 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
This is a pilot, randomized, double-blinded, placebo-controlled, 12-month trial of 50 patients with CKD stage 3b-4 with metabolic acidosis to examine the effect of sodium bicarbonate therapy on cognitive and cerebrovascular function.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sodium Bicarbonate Tablets | Participants will be given sodium bicarbonate at 0.5 mEq/kg-LBW/day for 12 months |
| DRUG | Placebo | Participants will be given placebo at 0.5 mEq/kg-LBW/day for 12 months |
Timeline
- Start date
- 2021-02-01
- Primary completion
- 2023-08-30
- Completion
- 2023-08-30
- First posted
- 2020-10-23
- Last updated
- 2024-12-20
- Results posted
- 2024-12-20
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04600323. Inclusion in this directory is not an endorsement.