NCT04581811

Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS)

Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS): A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: University of Alabama at Birmingham · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Prone positioning is one of the few therapies known to improve mortality in ARDS. Traditionally, patients are proned for 16 hours per 24 hour period. Some retrospective data suggests improvement may persist beyond 16 hours. We aim to perform a pilot study comparing traditional prone positioning to prolonged prone positioning in patients with COVID-induced ARDS.

Conditions

• ARDS
• Covid19
• Acute Hypoxemic Respiratory Failure

Interventions

Type	Name	Description
OTHER	Prolonged Proned Positioning	Patients will be placed in the prone position for 24 hours followed by 8 hours supine for consecutive periods for the duration of the study period
OTHER	Traditional Proning Arm	Patients will be placed in the prone position for 16 hours followed by 8 hours supine for consecutive periods for the duration of the study period

Timeline

• Start date: 2020-11-10
• Primary completion: 2021-03-20
• Completion: 2021-03-20
• First posted: 2020-10-09
• Last updated: 2022-03-31
• Results posted: 2022-03-31

Locations

1 site across 1 country: United States