Clinical Trials Directory

Trials / Completed

CompletedNCT04442503

A Study to Evaluate the Efficacy and Safety of SAGE-217 in Participants With Severe Postpartum Depression (PPD)

A Randomized, Double-Blind, Placebo-controlled Study Evaluating the Efficacy and Safety of SAGE-217 in the Treatment of Adults With Severe Postpartum Depression

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
200 (actual)
Sponsor
Biogen · Industry
Sex
Female
Age
18 Years – 45 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if treatment with SAGE-217 reduces depressive symptoms in females with severe postpartum depression (PPD) as compared to placebo.

Detailed description

This study was previously posted by Sage Therapeutics. In November 2023, sponsorship of the trial was transferred to Biogen.

Conditions

Interventions

TypeNameDescription
DRUGSAGE-217SAGE-217 oral capsules.
DRUGPlaceboSAGE-217 matched-placebo oral capsules.

Timeline

Start date
2020-06-08
Primary completion
2022-03-15
Completion
2022-04-12
First posted
2020-06-22
Last updated
2023-11-30
Results posted
2023-06-22

Locations

82 sites across 3 countries: United States, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04442503. Inclusion in this directory is not an endorsement.