| Recruiting | HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Pre NCT06175104 | Children's Hospital Medical Center, Cincinnati | N/A |
| Recruiting | A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it NCT07047820 | Biogen | — |
| Completed | A Study to Assess the Safety and Efficacy of Oral LPCN 1154A in Women With Severe PPD NCT06979544 | Lipocine Inc. | Phase 3 |
| Recruiting | Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression NCT06877104 | University of Pennsylvania | N/A |
| Recruiting | IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression NCT06746337 | University of Washington | N/A |
| Recruiting | Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes NCT06702722 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Implementation of a Psychoeducational Intervention in New Mothers NCT06512025 | Alba Roca | N/A |
| Recruiting | TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and A NCT06364488 | BlueSkeye AI | N/A |
| Recruiting | Validation of the French Version of the Edinburgh Postnatal Depression Scale (EPDS) Postnatally in the Father NCT06772701 | Groupe Hospitalier du Havre | N/A |
| Completed | The Use of the Diary in Neonatal Pathology: a Mixed-method Study for Collecting and Analyzing the Experience o NCT06316193 | IRCCS Ospedale San Raffaele | — |
| Completed | A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depr NCT06285916 | DuKang Pharmaceuticals, Inc. | Phase 2 |
| Recruiting | Evaluation of Access to Screening for Post-partum Depression Via the Postnatal Interview Within 8 Weeks of Bir NCT06469476 | Centre Hospitalier de Troyes | — |
| Unknown | Cerebral Synchronization Between Mothers and Their Newborns During Breastfeeding NCT05821569 | IRCCS Burlo Garofolo | — |
| Recruiting | From Prevention to Treatment: How Biological Rhythms Can Maintain Perinatal Mental Health NCT06246214 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Determining the Effect of Telephone Counseling Service Provided to Primiparous Mothers on Postpartum Depressio NCT06070168 | Ondokuz Mayıs University | N/A |
| Completed | Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1) NCT05907213 | Grace Lim, MD, MS | Phase 1 |
| Recruiting | Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period. NCT05961306 | University Hospital, Ghent | — |
| Completed | The Feasibility, Usability and Satisfaction of an Online Tool for Perinatal Mental Health Problems NCT06035159 | University Hospital, Ghent | N/A |
| Active Not Recruiting | Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women NCT05552053 | Cedars-Sinai Medical Center | Phase 2 / Phase 3 |
| Completed | Efficacy of Mother's Time in Ethiopia NCT05806463 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Unknown | A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care NCT04998721 | University of Washington | Phase 2 |
| Unknown | The Effect of Baby Massage on Postpartum Depression and Maternal Attachment NCT05813782 | Tokat Gaziosmanpasa University | N/A |
| Completed | Mother and Baby Yoga Study - Early Postnatal Yoga and Mental Health NCT06056609 | York Teaching Hospitals NHS Foundation Trust | N/A |
| Completed | Thinking Healthy Program-Technology Assisted (THP-TA) NCT05353491 | Human Development Research Foundation, Pakistan | N/A |
| Completed | Integrated Psychological Program for Management of Postnatal Depression and Persistent Postpartum Pain After C NCT05285215 | KK Women's and Children's Hospital | N/A |
| Unknown | Immune/Inflammatory Biomarkers in Postpartum Depression NCT05784116 | IRCCS San Raffaele | — |
| Completed | The Effect of Stress Reduction Program on Pregnancy Process and Mental Health in High Risk Pregnant Women NCT05573009 | Istanbul University | N/A |
| Completed | eMBC for Perinatal Depression and Anxiety NCT04836585 | Women's College Hospital | N/A |
| Completed | To Evaluate the Effectiveness of a Virtual and Telephone Intervention for the Prevention of Postpartum Depress NCT05110456 | St. Justine's Hospital | N/A |
| Active Not Recruiting | Enhancing Mental and Physical Health of Women Veterans NCT05050266 | VA Office of Research and Development | N/A |
| Completed | Estimating the Prevalence of Postpartum Anxiety and Depression in the Context of the Coronavirus Disease (COVI NCT04852757 | Fondation Hôpital Saint-Joseph | — |
| Unknown | Feasibility of M-health Version of "What Were We Thinking" Intervention to Promote Maternal Postpartum Mental NCT04847076 | Universidad del Desarrollo | N/A |
| Completed | MOVIN Pilot Randomized Controlled Trial NCT04680585 | Women's College Hospital | N/A |
| Unknown | Pregnancy Without Psychosocial Stress NCT04853693 | National Institute of Mental Health, Czech Republic | N/A |
| Completed | The Effect of the Close Collaboration With Parents Intervention - Estonian Study NCT06258655 | University of Turku | N/A |
| Completed | Intensified Tactile Contact With a Newborn Andt Emotional Transformation of the Mother NCT05820958 | The Jerzy Kukuczka Academy of Physical Education in Katowice | N/A |
| Completed | A Study to Evaluate the Efficacy and Safety of SAGE-217 in Participants With Severe Postpartum Depression (PPD NCT04442503 | Biogen | Phase 3 |
| Completed | "Investigation of the Relationship Between New Coronary Virus Disease (COVID-19) and Anxiety and Depressive Sy NCT04384887 | Kanuni Sultan Suleyman Training and Research Hospital | — |
| Withdrawn | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression NCT04211467 | ProgenaBiome | — |
| Completed | Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model NCT04051320 | University of North Carolina, Chapel Hill | Phase 2 |
| Withdrawn | CALM for Pregnant and Post-Partum Women NCT03351465 | University of California, Los Angeles | N/A |
| Completed | Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study NCT04154423 | University of California, San Francisco | N/A |
| Unknown | MAMA NO STRESS Project. The Effects of the "HAPPY MAMA" Intervention NCT04093791 | University of Roma La Sapienza | N/A |
| Completed | Examining the Effectiveness of Transdiagnostic, Internet-Delivered Cognitive Behaviour Therapy in New Mothers NCT04012580 | University of Regina | N/A |
| Completed | Look - Your Baby is Talking to You. NCT04169334 | Copenhagen University Hospital, Hvidovre | N/A |
| Completed | CHS Nurses Clinical Competence in Detecting Signs of PPD in Non-Native Speaking Immigrant Mothers' NCT04167709 | Lund University | N/A |
| Completed | Tracking Depression Symptoms With a Health Chatbot NCT03990389 | University of Chicago | N/A |
| Completed | Inhaled Oxytocin and HPA Axis Reactivity NCT03593473 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Randomized Controlled Trial of the Alma Peer Mentoring Program for Pregnant Women Experiencing Depression NCT02883686 | University of Colorado, Boulder | N/A |
| Completed | Screening for Depression and Anxiety in Pregnant and Postpartum Women: Evaluating Prevalence, Risk Factors, an NCT06664593 | University Hospital, Ghent | — |
| Completed | How Does Mindful Mood Balance for Moms Work? NCT05000879 | University of Colorado, Boulder | N/A |
| Completed | Meditation for NICU Moms NCT03574766 | St. Louis University | N/A |
| Completed | RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood NCT03646539 | Stanford University | N/A |
| Completed | Minimum Intervention to Maintain a Postpartum Depression Prevention Program in Clinics Serving Low-income Wome NCT03267563 | Michigan State University | N/A |
| Completed | Perinatal Interpersonal Psychotherapy Group for Distressed Women NCT06431672 | Chung Shan Medical University | N/A |
| Completed | A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression NCT03460756 | Marinus Pharmaceuticals | Phase 2 |
| Recruiting | MOther-Child Interaction Assessment TRAINING for Pediatricians NCT03300713 | University Hospital, Lille | N/A |
| Completed | Decreasing Stunting by Reducing Maternal Depression in Uganda: A Cluster Randomized Controlled Trial (CRCT) fo NCT03573713 | Food for the Hungry | N/A |
| Completed | The Effect of an Exercise Program in Reducing the Severity of Postpartum Depression in Women NCT04043533 | Didem Kucukkelepce | N/A |
| Completed | A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression NCT03228394 | Marinus Pharmaceuticals | Phase 2 |
| Active Not Recruiting | CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery) NCT03167905 | KK Women's and Children's Hospital | Phase 2 / Phase 3 |
| Completed | Post-natal Depression and Chronic Stress NCT03088319 | Institut de Recherche Biomedicale des Armees | — |
| Completed | Group CBT for PPD in the Public Health Setting NCT03039530 | McMaster University | N/A |
| Completed | CSE v. Epidural for Postpartum Depression NCT03022526 | Grace Lim, MD, MS | N/A |
| Completed | Online Collaborative Learning Intervention to Prevent Perinatal Depression NCT02121015 | University of Illinois at Chicago | N/A |
| Completed | Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project NCT02664467 | Ospedale Regionale di Lugano | N/A |
| Completed | Preventing Postpartum Depression With Intranasal Oxytocin NCT02505984 | Massachusetts General Hospital | Phase 2 |
| Completed | Labor Pain and Postpartum Behavioral Health Outcomes Study NCT02692404 | University of Pittsburgh | — |
| Completed | The Northern Babies Longitudinal Study NCT02538497 | University of Tromso | N/A |
| Completed | Effectiveness of a Web-based Nursing Intervention in the Reduction of Postpartum Depression and Parenting Stre NCT02843022 | Saint Anselm College | N/A |
| Completed | Perinatal Emotion and Relationships Longitudinal Study NCT03027037 | University of Colorado, Boulder | — |
| Completed | The Impact of Creative Interventions on Symptoms of Postnatal Depression NCT02526407 | Royal College of Music | N/A |
| Completed | The Impact of Creative Interventions on Symptoms of Postnatal Depression (Cohort Study) NCT02526433 | Royal College of Music | — |
| Completed | The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression NCT02769858 | University of Michigan | N/A |
| Completed | The Correlation Between Prelabor Analgesic Plan and Actual Labor Analgesia With Satisfaction, Postpartum Depre NCT02495350 | Rabin Medical Center | — |
| Completed | The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience NCT02454322 | Northwestern University | — |
| Completed | Mindfulness Based Childbirth and Parenting Education - RCT of Effects on Parent and Child Health NCT02441595 | Karolinska Institutet | N/A |
| Completed | Neuraxial Labor Analgesia and the Incidence of Postpartum Depression NCT02823418 | Peking University First Hospital | — |
| Terminated | Prophylactic Use of Postpartum Sertraline to Prevent Postpartum Depression NCT02235064 | The Cooper Health System | N/A |
| Unknown | SPRING Cluster Randomised Controlled Trial NCT02059863 | London School of Hygiene and Tropical Medicine | N/A |
| Terminated | Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum NCT01842542 | Neuronetics | N/A |
| Completed | Follow up of Mothers Suspected of Postpartum Depression NCT02559986 | Indiana University | — |
| Completed | Type II Diabetes Mellitus in Patients Exposed to Pravastatin and Paroxetine NCT01602913 | GlaxoSmithKline | — |
| Completed | Doula Home Visiting Randomized Trial NCT01947244 | University of Chicago | N/A |
| Completed | IMI PROTECT(WP2): Antidepressants & Fractures NCT01587729 | GlaxoSmithKline | — |
| Completed | Efficacy of Yoga for Postpartum Depression NCT02213601 | University of Iowa | N/A |
| Completed | Exploratory Trial of a Group Psychological Intervention for Postnatal Depression in British Mother's of South NCT01838889 | Lancashire Care NHS Foundation Trust | N/A |
| Completed | Madres Para la Salud (Mothers for Health) NCT01908959 | Arizona State University | N/A |
| Completed | Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT NCT00951717 | Icahn School of Medicine at Mount Sinai | N/A |
| Terminated | Controlled Randomised Trial of Ferric Carboxymaltose and Oral Iron to Treat Postpartum Anemia NCT00929409 | Norwegian University of Science and Technology | Phase 2 / Phase 3 |
| Completed | Randomised Control Trial of a Complex Intervention for Postnatal Depression NCT01309516 | Pakistan Institute of Living and Learning | Phase 2 |
| Completed | Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depr NCT00602355 | Women and Infants Hospital of Rhode Island | Phase 2 |
| Completed | Repetitive Transcranial Magnetic Stimulation in Postpartum Depression NCT01452321 | University of Sao Paulo General Hospital | Phase 2 |
| Completed | Depression Prevention for Pregnant Women on Public Assistance NCT00601757 | Women and Infants Hospital of Rhode Island | Phase 2 |
| Unknown | Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale NCT00251342 | Chinese University of Hong Kong | Phase 2 / Phase 3 |
| Completed | Interpersonal Treatment Program to Prevent Depression and Post-Traumatic Stress Disorder in Low-Income Pregnan NCT00602732 | Butler Hospital | Phase 1 |
| Completed | Use of Omega-3 Fatty Acids for Perinatal Depression NCT00402389 | University of Arizona | Phase 2 |
| Completed | Effectiveness of Supplemental Calcium in Preventing Postpartum Depression NCT00228033 | Oregon Health and Science University | Phase 4 |
| Completed | Group Therapy for Postpartum Depression NCT00051246 | University of Wisconsin, Madison | N/A |
| Completed | Prevention of Postpartum Depression in Low-Income Women NCT00053651 | Butler Hospital | Phase 1 |
| Completed | Clinician Managed Interpersonal Psychotherapy NCT00043602 | University of Iowa | EARLY_Phase 1 |
| Completed | Doula Support for Young Mothers: A Randomized Trial NCT01925664 | University of Chicago | N/A |