NCT04377841

Facial Demodicosis and Ocular Demodicosis

Clinical Correlation Between Facial Demodicosis and Ocular Demodicosis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

To understand the association between facial demodicosis and ocular demodicosis, we plan to enroll patients with facial demodicosis, ocular demodicosis, or both, in order to analyze their clinical presentations, the density of Demodex infestation over facial skin and eyelashes, and possible risk factors of the two diagnoses.

Detailed description

Although facial demodicosis and ocular demodicosis are described in a variety of clinical presentations, the association between the two diagnoses is not clearly identified. Clinically, we plan to enroll 120 patients with facial demodicosis, ocular demodicosis. We will obtain their basic information, medical history, medication, and lifestyle. We will evaluate their clinical features. We will also perform quantitative tests including direct microscopic examination and cilia epilation test: 1. Direct microscopic examination: On glabella and bilateral cheeks, follicular contents in the 1-cm × 1-cm area will be squeezed out. The contents are transferred onto a glass slide, covered with mineral oil and a cover slide, and examined under the microscope. 2. Epilation: Four (4) non-adjacent cilia will be pulled from each upper eyelid and examined under the microscope. The total Demodex counts are recorded. We will analyze the clinical presentations, the density of Demodex infestation, and possible risk factors of the two diagnoses.

Conditions

• Demodex Infestation
• Rosacea
• Blepharitis
• Meibomian Gland Dysfunction
• Pityriasis Folliculorum

Timeline

• Start date: 2020-04-13
• Primary completion: 2020-12-14
• Completion: 2020-12-14
• First posted: 2020-05-06
• Last updated: 2020-05-06

Locations

1 site across 1 country: Taiwan