| Not Yet Recruiting | Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions NCT07290426 | Candela Corporation | N/A |
| Recruiting | Acupuncture for Refractory Rosacea: A Study on Its Effectiveness and Safety NCT07296497 | Xiangya Hospital of Central South University | N/A |
| Completed | Brimonidine 0.33% for Rosacea-Related Facial Erythema NCT07431476 | Istanbul Training and Research Hospital | Phase 4 |
| Completed | Analysis of Factors Associated With the Efficacy of 595-nm Pulsed Dye Laser Treatment for Rosacea NCT07410533 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Not Yet Recruiting | Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermat NCT06763367 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Completed | Comparative Study of Low-Energy 1064nm Laser and DPL in Rosacea Treatment NCT06915636 | Second Affiliated Hospital of Xi'an Jiaotong University | N/A |
| Completed | Combined Therapy of 532-nm KTP and Microsecond 1064-nm Nd:YAG Laser for Rosacea NCT07250165 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Evaluation of the Efficacy and Tolerance of Two Cosmetic Products in Subjects With Rosacea NCT06582043 | NAOS Argentina S.A. | N/A |
| Completed | Bioequivalence Study of Ivermectin 1% Cream and Soolantra (Ivermectin) 10 mg/g Cream NCT06557603 | Humanis Saglık Anonim Sirketi | Phase 1 |
| Unknown | Assessment of Rosacea Patients' Clinical Trial Experiences NCT05747391 | Power Life Sciences Inc. | — |
| Recruiting | Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Pati NCT06312813 | Wright State University | Phase 2 |
| Completed | Efficacy and Safety of Different Dose Regimens of Gabapentin for Treating Erythema/Flushing in Rosacea: A Rand NCT06776445 | First Affiliated Hospital of Chongqing Medical University | Phase 1 |
| Completed | The Impact of Untreated Depression and Anxiety Among Patients With Skin Diseases in Jeddah, Saudi Arabia. NCT07046039 | King Abdulaziz University | — |
| Completed | FMRF Combined With 30% SSA in the Treatment of Rosacea NCT06969300 | Second Affiliated Hospital of Xi'an Jiaotong University | N/A |
| Recruiting | Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic I NCT06072066 | Integrative Skin Science and Research | N/A |
| Unknown | Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of Rosacea NCT06307288 | Second Affiliated Hospital of Xi'an Jiaotong University | Phase 4 |
| Completed | Potassium-titanyl Phosphate (KTP) Laser vs KTP Laser and Ivermectin Cream for Facial Rosacea NCT06033352 | Insel Gruppe AG, University Hospital Bern | Phase 2 |
| Completed | Changes in PACAP, CGRP, and VIP Levels in Rosacea Patients on Systemic Isotretinoin and Their Association with NCT06873087 | SB Istanbul Education and Research Hospital | Phase 4 |
| Recruiting | The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis NCT05942248 | Integrative Skin Science and Research | N/A |
| Recruiting | Determinants of Chronic Inflammatory Skin Disease Trajectories NCT05928169 | University Hospital Schleswig-Holstein | — |
| Unknown | Effectivity and Safety of Metronidazole 1% Cream in Rosacea Therapy NCT05861310 | Dr.dr.Irma Bernadette, SpKK (K) | Phase 1 |
| Unknown | Potassium Titanyl Phosphate Laser Versus Pulsed Dye Laser for Rosacea - a Prospective Study NCT05771298 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Withdrawn | A Pilot Study Testing the Effects of Chemical Peels in Patients With Rosacea NCT04889703 | University of Texas Southwestern Medical Center | N/A |
| Completed | Clinical Trial to Evaluate the Effect of a Probiotic Mixture on the Rosacea Evolution NCT05815511 | Bionou Research, S.L. | N/A |
| Completed | Impact of DFD-29 on Microbial Flora of Healthy, Adult Human Subjects When Administered Over 16 Weeks NCT05597462 | Journey Medical Corporation | Phase 1 |
| Unknown | Brimonidine in Rosacea NCT05401422 | Cairo University | N/A |
| Completed | Evaluation of the Safety and Efficacy of Topical Roflumilast Cream in the Treatment of Facial Papulopustular R NCT05278624 | Dermatology Consulting Services, PLLC | Phase 2 |
| Unknown | Clinical Observation of Botulinum Toxin A Treatment in the Treatment of Rosacea NCT06282679 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Completed | A Study of a Polymeric Surfactant Technology Cleanser in Sensitive Skin Participants NCT05094700 | Johnson & Johnson Consumer Inc. (J&JCI) | N/A |
| Completed | Therapeutic Effects of Topical Herbal Medicine -Rhubarb Ointment on Rosacea NCT05045469 | Chang Gung Memorial Hospital | Phase 2 |
| Unknown | Clinical Benefit of M89PB in Subjects With Rosacea Associated With Erythema and Sensitive Skin NCT04898582 | Institute of Skin and Product Evaluation, Italy | N/A |
| Completed | CGB-400 Topical Gel for the Treatment of Inflammatory Lesions of Rosacea NCT04886739 | CAGE Bio Inc. | Phase 2 |
| Completed | Rosacea and Ivermectin NCT04275999 | Wake Forest University Health Sciences | Phase 2 |
| Completed | M89PF in Rosacea Associated With Erythema and Sensitive Skin NCT05562661 | Cosmetique Active International | — |
| Unknown | Efficacy and Tolerability of Erenumab in the Management of Persistent Redness and Flushing in Rosacea NCT04419259 | Messoud Ashina | Phase 2 |
| Unknown | Facial Demodicosis and Ocular Demodicosis NCT04377841 | National Taiwan University Hospital | — |
| Completed | Use of the SpiderMass for in Vivo Analysis of the Skin in Five Chronic Inflammatory Dermatosis NCT04472546 | Pierre Fabre Dermo Cosmetique | N/A |
| Terminated | Skin Imaging to Inform Laser Treatments NCT04336163 | University of California, Irvine | N/A |
| Active Not Recruiting | Analysis of the Microbiome in Rosacea NCT04108897 | Johns Hopkins University | EARLY_Phase 1 |
| Completed | Role of the Sympathetic Nervous System in Rosacea NCT03989492 | Kristen Metzler-Wilson | N/A |
| Completed | A Clinical Endpoint Bioequivalence Study of "Oxymetazoline Hydrochloride Cream" NCT03954444 | Actavis Inc. | Phase 3 |
| Completed | 4 Week In-Use Study Evaluating How Well-Tolerated a Skin Care Product Is on Adults With Facial Redness NCT03841032 | Bayer | N/A |
| Withdrawn | Intense Pulsed Light as an Adjunctive to Bromonidine for the Treatment of Rosacea NCT03053700 | Rabin Medical Center | Phase 4 |
| Completed | PACAP38 Induced Headache and Rosacea-like Symptoms in Patients With Rosacea NCT03878784 | Danish Headache Center | N/A |
| Completed | CGB-400 for the Reduction of Facial Redness and Bumps and Blemishes NCT04508205 | CAGE Bio Inc. | Phase 1 |
| Completed | CGB-400 for the Reduction of Facial Redness NCT04508660 | CAGE Bio Inc. | Phase 1 |
| Completed | Deep Phenotyping of Rosacea and Migraine NCT03872050 | Danish Headache Center | — |
| Completed | A Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Rosacea NCT03590366 | AOBiome LLC | Phase 2 |
| Suspended | Evaluation of Topical Application of BMX-010 in Subjects With Rosacea NCT03756389 | BioMimetix JV, LLC | Phase 2 |
| Completed | The Suitability of Two Skin Care Regimens in Moderate to Severe Facial Rosacea NCT03392558 | Burt's Bees Inc. | N/A |
| Completed | To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea NCT03689010 | Sun Pharmaceutical Industries, Inc. | Phase 1 |
| Completed | Safety and Tolerability of Oxymetazoline and Energy-Based Therapy in Participants With Rosacea NCT03380390 | Aclaris Therapeutics, Inc. | Phase 4 |
| Completed | Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment NCT03424304 | Cutera Inc. | N/A |
| Completed | Lipidome and Microbiome Profile of the Eye in Rosacea NCT03655197 | University of California, Davis | EARLY_Phase 1 |
| Completed | Study to Evaluate the Safety and Efficacy of Topical Minocycline Gel in Patients With Papulopustular Rosacea NCT03263273 | Hovione Scientia Limited | Phase 2 |
| Completed | An Evaluation of the Reduction in Erythema in Adult Patients With Moderate to Severe Persistent Facial Erythem NCT03352323 | Padagis LLC | Phase 3 |
| Completed | A Controlled Study to Assess the Efficacy, Safety and Tolerability of Oral DFD-29 Extended Release Capsules NCT03340961 | Dr. Reddy's Laboratories Limited | Phase 2 |
| Completed | Treatment of Dilated Blood Vessels on the Cheeks With a New Yellow Laser and a Traditional Green Laser NCT03472859 | Tampere University Hospital | N/A |
| Unknown | Characterization of the Facial and Gut Microbiome in Rosacea NCT03228927 | The Acne Cure Alliance | — |
| Completed | A Study of Patient Concerns and Treatment Satisfaction in Patients Being Treated With Finacea Foam for Rosacea NCT03193372 | LEO Pharma | — |
| Completed | Oracea Soolantra Association in Participants With Severe Rosacea NCT03075891 | Galderma R&D | Phase 4 |
| Completed | Assessing the Quality of Life of Patients With Rosacea NCT06271135 | Medical University of Bialystok | N/A |
| Completed | Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component) NCT03253666 | Harvard School of Public Health (HSPH) | — |
| Completed | Bioequivalence Study of Two Treatments in the Treatment of Inflammatory Lesions of Rosacea on the Face NCT02800148 | Padagis LLC | Phase 3 |
| Unknown | EVALUATION OF THE EFFECT OF THE PERFECTA V-BEAM LASER ON ROSACEA NCT03211585 | Syneron Medical | N/A |
| Completed | A Study to Evaluate Safety and Equivalence of Generic Azelaic Acid Foam and Finacea® Foam in Participants With NCT03287791 | Actavis Inc. | Phase 3 |
| Completed | A Study to Assess the Efficacy, Safety and Tolerability of DFD-04 NCT02828241 | Dr. Reddy's Laboratories Limited | Phase 2 |
| Completed | Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation. NCT02806414 | University of California, San Diego | Phase 1 / Phase 2 |
| Completed | To Evaluate the Therapeutic Equivalence and Safety of Azelaic Acid 15% Topical Gel NCT03094403 | Sun Pharmaceutical Industries, Inc. | Phase 1 |
| Completed | Pharmacokinetics of Doxycycline in Skin of Healthy Volunteers NCT03478436 | Medical University of Vienna | Phase 1 |
| Completed | Internet Surveys and Their Impact on Adherence for Rosacea NCT03048058 | Wake Forest University Health Sciences | Phase 4 |
| Completed | Comparative Safety and Efficacy of Two Treatments in the Treatment of Inflammatory Lesions of Rosacea NCT02795117 | Padagis LLC | Phase 3 |
| Completed | Timolol for the Treatment of Acne and Rosacea NCT02774590 | Johns Hopkins University | Phase 1 |
| Completed | Genetic Basis of Rosacea Study (Control) NCT02749786 | Stanford University | N/A |
| Completed | Study to Evaluate the Safety and Efficacy of a Once-Daily CLS001 Topical Gel Versus Vehicle NCT02547441 | Maruho Co., Ltd. | Phase 3 |
| Completed | MirvasO Soolantra Association In the Treatment of Moderate to Severe rosaCea. NCT02616250 | Galderma R&D | Phase 4 |
| Completed | Mirvaso® Utilisation and Patient Satisfaction Evaluation (MUSE) NCT02637232 | Galderma R&D | — |
| Completed | Study to Evaluate the Long-term Safety of a Once-Daily Omiganan Topical Gel NCT02576847 | Maruho Co., Ltd. | Phase 3 |
| Completed | Study to Evaluate the Safety and Efficacy of a Once-Daily CLS001 Topical Gel Versus Vehicle NCT02576860 | Maruho Co., Ltd. | Phase 3 |
| Completed | Safety and Efficacy Study of a Topical Minocycline Foam in Patients With Papulopustular Rosacea NCT02601963 | Vyne Therapeutics Inc. | Phase 2 |
| Unknown | Demodex Density, Immune Response and Oxidative Stress in Rosacea Patients NCT02556827 | Istanbul Training and Research Hospital | — |
| Completed | Comparative Safety and Efficacy of Two Rosacea Products in the Treatment of Facial Erythema of Rosacea NCT02385240 | Padagis LLC | Phase 3 |
| Completed | Preferences & Treatment Satisfaction Drivers in Rosacea Patients NCT02602470 | LEO Pharma | — |
| Completed | A Study to Evaluate the Safety and Efficacy of PAC-14028 Cream in Rosacea NCT02583009 | Amorepacific Corporation | Phase 2 |
| Completed | Mirvaso in Use Study NCT02249065 | Galderma R&D | Phase 4 |
| Completed | Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With Moderate t NCT02289352 | Actavis Inc. | Phase 3 |
| Completed | Safety and Efficacy of Oxymetazoline HCl Cream 1.0% in Patients With Persistent Erythema Associated With Rosac NCT02132117 | Allergan | Phase 3 |
| Completed | Efficacy and Safety of AGN-199201 in Patients With Persistent Erythema Associated With Rosacea NCT02131636 | Allergan | Phase 3 |
| Completed | Ultherapy® for the Treatment of Erythematotelangiectatic Rosacea NCT02144181 | Ulthera, Inc | N/A |
| Completed | Photodynamic Therapy for Papulopustular Rosacea NCT02075671 | George Washington University | Phase 4 |
| Completed | Effect of CD07805/47 Gel in Rosacea Flushing NCT02300129 | Galderma R&D | Phase 2 |
| Completed | A Long-Term Safety and Efficacy Study AGN-19920 in Patients With Persistent Erythema Associated With Rosacea NCT02095158 | Allergan | Phase 3 |
| Completed | RosaC-RF : Bipolar Radiofrequency vs Doxycycline in Rosacea NCT02204254 | Centre Hospitalier Universitaire de Nice | N/A |
| Unknown | Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis NCT02036229 | Rabin Medical Center | Phase 3 |
| Completed | A Safety and Efficacy Study of DRM02 in Subjects With Rosacea NCT01993446 | Dermira, Inc. | Phase 2 |
| Completed | Assessment of the Rosacea Prevalence in the General Population NCT02292797 | Galderma R&D | — |
| Completed | Patient-Reported Outcome Of Facial Erythema (PROOF) NCT01885000 | Galderma R&D | Phase 3 |
| Completed | At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurolo NCT01931644 | Sanguine Biosciences | — |
| Completed | A Study to Evaluate the Safety and Clinical Study of Azelaic Acid Gel 15% in Patients With Moderate Facial Ros NCT02120924 | Actavis Inc. | Phase 3 |
| Unknown | An Evaluation of PDI-320 in Comparison to Its Monads in Adults With Rosacea NCT01828177 | PreCision Dermatology, Inc. | Phase 2 |
| Withdrawn | Rifaximin Treatment of Papulopustular Rosacea NCT01359228 | University of California, San Francisco | Phase 2 |
| Completed | Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema of Rosacea NCT01789775 | Galderma R&D | Phase 3 |
| Completed | AGN-199201 for the Treatment of Erythema With Rosacea NCT01735201 | Allergan | Phase 2 |
| Completed | A Study to Evaluate the Safety, Tolerability, and Effects of Anatabloc® Crème in Rosacea NCT01740934 | Rock Creek Pharmaceuticals, Inc. | N/A |
| Completed | Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of R NCT01659853 | Galderma R&D | Phase 3 |
| Completed | Rosacea Prevalence in General Population - Pilot Study NCT02292836 | Galderma R&D | — |
| Completed | A Double-Blinded, Randomized Placebo Controlled Pilot Study Comparing the Efficacy and Safety of Incobotulinum NCT01614743 | DeNova Research | Phase 2 |
| Completed | Study of Inter- and Intra-rater Reliability of the Clinician Erythema Assessment Scale NCT01636765 | Allergan | — |
| Completed | Genetic Basis of Rosacea NCT02787616 | Stanford University | — |
| Completed | Safety and Tolerability of AGN-199201 in Patients With Erythema Associated With Rosacea NCT01579084 | Allergan | Phase 1 |
| Completed | Safety and Efficacy of the Luxe Device to Treat Facial Wrinkles and Rosacea NCT01618864 | Syneron Medical | N/A |
| Completed | A Study of DER 45-EV Gel to Treat Rosacea NCT00940992 | Sol-Gel Technologies, Ltd. | Phase 2 |
| Completed | Pulsed Dye Laser (PDL) vs. Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness NCT01529996 | Northwestern University | N/A |
| Completed | A Study of Laropiprant (MK-0524) in Participants With Moderate to Severe Erythematotelangiectatic Rosacea (MK- NCT01451619 | Merck Sharp & Dohme LLC | Phase 1 |
| Completed | Evaluation of Relapse, Efficacy and Safety of Long-term Treatment With Oracea® vs Placebo NCT01426269 | Galderma R&D | Phase 4 |
| Completed | A Therapeutic Equivalence Study of Two Metronidazole 1%Topical Gel Treatments for Patients With Rosacea NCT01513863 | Sun Pharmaceutical Industries, Inc. | Phase 1 |
| Completed | Effects of Aminocaproic Acid (ACA) on Rosacea-specific Inflammation NCT01398280 | University of California, San Diego | EARLY_Phase 1 |
| Completed | Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With R NCT01355458 | Galderma R&D | Phase 3 |
| Completed | Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With R NCT01355471 | Galderma R&D | Phase 3 |
| Completed | Evaluation of Rosacea-related Inflammatory Biochemical Markers in Adult Skin When Treated With Oracea® vs Plac NCT01308619 | Galderma R&D | Phase 4 |
| Completed | Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea NCT01318733 | Galderma R&D | Phase 3 |
| Completed | Azelaic Acid on Demodex Counts in Rosacea NCT03035955 | Wake Forest University | Phase 2 / Phase 3 |
| Completed | Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea NCT01174030 | Galderma R&D | Phase 2 |
| Completed | Combination Gel and Vascular ND in Mild to Moderate Rosacea NCT01631656 | Wake Forest University Health Sciences | N/A |
| Terminated | Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Rosacea Patients NCT01134991 | Vyne Therapeutics Inc. | Phase 2 |
| Completed | Efficacy of Oral Minocycline (Solodyn) and Oral Minocycline (Solodyn) Plus Azelaic Acid (Finacea) for Acne Ros NCT05014906 | Dermatology Specialists Research | Phase 4 |
| Terminated | Atralin Gel for the Treatment of Rosacea NCT01125930 | Lisa E. Maier | Phase 3 |
| Completed | The Role of Topically Dissolved Oxygen (TDO) to Ameliorate Signs of Photodamage NCT00991198 | Aria Aesthetics Inc. | Phase 2 |
| Completed | ORCA - Oracea® for Rosacea: A Community-based Assessment NCT00892281 | Galderma R&D | Phase 4 |
| Completed | Safety and Efficacy Study of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel to Treat Rosacea NCT00823901 | Massachusetts General Hospital | Phase 2 / Phase 3 |
| Completed | Potential Research Study Participant Registry NCT00710489 | University of California, Davis | — |
| Completed | A Study to Determine the Safety and Efficacy of Atralin (Tretinoin 0.05%) Gel for the Treatment of Rosacea NCT00621218 | Coria Laboratories, Ltd. | Phase 2 |
| Completed | An Evaluation of the Cosmetic Appearance of Metronidazole Gel (MetroGel®) 1% NCT00668655 | Galderma R&D | — |
| Completed | A Clinical Study Evaluating the Safety and Efficacy of IDP-115 in Patients With Rosacea NCT00667173 | Dow Pharmaceutical Sciences | Phase 2 |
| Completed | Safety and Effectiveness of Subconjunctival Injection of Bevacizumab in the Treatment of Corneal Neovasculizat NCT00681603 | National Taiwan University Hospital | N/A |
| Completed | Safety and Efficacy Study to Compare Two Rosacea Treatment Regimens NCT00495313 | CollaGenex Pharmaceuticals | Phase 4 |
| Completed | Assess the Ability of MetroGel 1% to Deliver Moisture to Facial Skin After a Single Application NCT00436527 | Galderma R&D | Phase 4 |
| Terminated | Zinc Sulfate in the Treatment of Rosacea: A Randomized, Controlled Trial NCT00395226 | Essentia Health | N/A |
| Completed | Efficacy of Topical Cyclosporin for Ocular Rosacea NCT00348335 | Ophthalmic Consultants of Long Island | Phase 4 |
| Completed | A Phase II, Randomized Study of ACZONE™ (Dapsone) Gel, 5% for Papulopustular Rosacea. NCT00249782 | Allergan | Phase 2 |
| Completed | Topical Agent for Treatment of Red Skin NCT00279890 | Mayo Clinic | Phase 1 |
| Completed | A Clinical Trial to Determine the Effects of 40 Mg Doxycycline Versus a Placebo Control for the Treatment of R NCT00126399 | CollaGenex Pharmaceuticals | Phase 3 |