Trials / Completed
CompletedNCT03478436
Pharmacokinetics of Doxycycline in Skin of Healthy Volunteers
Pharmacokinetics of DFD-09 (Doxycycline) Capsules, 40 mg in Skin of Healthy Volunteers Under Fed and Fasting Conditions - an Exploratory Microdialysis Study
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 6 (actual)
- Sponsor
- Medical University of Vienna · Academic / Other
- Sex
- Male
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
This study explored the impact of food on skin and plasma pharmacokinetics of doxycycline
Detailed description
Sub-antimicrobial dose doxycycline is approved for the treatment of rosacea. This work investigated the pharmacokinetics of doxycycline in skin and plasma of fed and fasting healthy volunteers receiving a 14-day treatment course with once daily 40 mg doxycycline. Dermal measurements were performed by means of in vivo microdialysis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Doxycycline | Doxycycline 40 mg capsules |
Timeline
- Start date
- 2016-07-01
- Primary completion
- 2016-10-25
- Completion
- 2016-10-25
- First posted
- 2018-03-27
- Last updated
- 2018-03-27
Locations
1 site across 1 country: Austria
Source: ClinicalTrials.gov record NCT03478436. Inclusion in this directory is not an endorsement.