Trials / Recruiting
RecruitingNCT04334031
Deployment o the Multidisciplinary Prospective Cohort Imminent
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 2,200 (estimated)
- Sponsor
- University Hospital, Lille · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions. Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite progress in this field, much remains to be done in clinical, therapeutic and fundamental research to address the efficacy, resistance and side-effects of treatment. These similarities between IMIDs have led the FHU IMMINeNT to propose the creation of a prospective, multidisciplinary clinical-biological database (IMMINeNT cohort), associated to a biobank, of patients with IMIDs. The main objectives of this database will be to identify new prognostic and therapeutic biomarkers in order to develop new therapeutic targets and biomarkers, to identify prognostic factors and determinants related to the activity, severity and quality of life of patients with IMIDs as well as to the response and tolerance to treatment.
Conditions
- Chronic Inflammatory Disease
- Angioedema
- Severe Asthma
- Lupus
- Atopic Dermatitis
- Psoriatic Arthritis
- Multiple Sclerosis
- Systemic Sclerosis
- Behçet Disease
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | Biobanking with genetic analysis | Patients included in the IMMINeNT cohort will be collected 7 blood samples for the research project at each revaluation visit. For patients who accepted, genetic analysis (DNA analysis) will be done on a part of those samples. |
| OTHER | SF-12 questionnaire | Patients included in the IMMINeNT cohort will be asked to complete SF-12 quality of life questionnaire. |
Timeline
- Start date
- 2020-07-20
- Primary completion
- 2031-07-01
- Completion
- 2031-07-01
- First posted
- 2020-04-03
- Last updated
- 2022-05-23
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04334031. Inclusion in this directory is not an endorsement.