Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04052581

Prospective Collection of Outcome Data Post POEM-TIF Procedure

Assessment of Safety and Outcomes in Patients Undergoing a Standard-of-care Combined POEM-TIF Procedure

Status
Withdrawn
Phase
Study type
Observational
Enrollment
0 (actual)
Sponsor
Johns Hopkins University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Per Oral Endoscopic Myotomy has been established as a safe and effective treatment of Achalasia type I and II; however, it is limited by post-procedure gastroesophageal reflux. Transoral Incisionless Fundoplication (TIF) has been introduced as the endoscopic gold standard for anti-reflux procedure. Recently, combined POEM-TIF has been performed successfully as a standard of care treatment for patients with severe GER after POEM. We aim to study the safety and feasibility of performing POEM-TIF (POEM and TIF in the same endoscopic session). This study will also put the groundwork for a randomized clinical trial to further study the clinical outcome of the POEM-TIF procedure.

Conditions

Interventions

TypeNameDescription
PROCEDUREPOEM-TIFTransoral Incisionless Fundoplication (TIF) following Per oral Endoscopic Myotomy (POEM) in the same session

Timeline

Start date
2023-07-01
Primary completion
2023-07-26
Completion
2023-07-26
First posted
2019-08-12
Last updated
2023-07-28

Source: ClinicalTrials.gov record NCT04052581. Inclusion in this directory is not an endorsement.