NCT04051567

Low-dose Aspirin for Prevention of Adverse Pregnancy Outcomes in Twin Pregnancies

Low-dose Aspirin for Prevention of Adverse Pregnancy Outcomes in Twin Pregnancies--A Multicenter, Prospective, Open, Randomized, Controlled Clinical Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 425 (estimated)
• Sponsor: Ministry of Science and Technology of the People´s Republic of China · Other Government
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Twin pregnancies are associated with increased risk of perinatal adverse outcomes , including preeclampsia , fetal growth restriction , preterm premature rupture of membranes and preterm birth. Low-dose aspirin was recommend by American College of Obstetricians and Gynecologists (ACOG) during pregnancy. In this trial, the investigators suppose that aspirin used in twin-pregnancies could improve adverse pregnancy outcomes.

Conditions

• Twin Pregnancy
• Preeclampsia
• Preterm Birth
• Fetal Growth Restriction

Interventions

Type	Name	Description
DRUG	Aspirin 100mg	In LDA group, patients were asked for taking 100mg aspirin per night;

Timeline

• Start date: 2018-11-01
• Primary completion: 2020-06-01
• Completion: 2020-12-01
• First posted: 2019-08-09
• Last updated: 2019-10-29

Locations

1 site across 1 country: China