Clinical Trials Directory

Trials / Terminated

TerminatedNCT04007367

A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive Disorder

A Phase 3, Randomized, Double-Blind, Placebo-controlled Study of the Efficacy and Safety of SAGE-217 With a Fixed, Repeated Treatment Regimen on Relapse Prevention in Adults With Major Depressive Disorder

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
53 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

This is a study with an Open-Label (OL) phase followed by a randomized, Double-Blind (DB), placebo-controlled phase to assess efficacy and safety of SAGE-217 on relapse prevention in adults with major depressive disorder (MDD).

Detailed description

This study was previously posted by Sage Therapeutics. In November 2023, sponsorship of the trial was transferred to Biogen.

Conditions

Interventions

TypeNameDescription
DRUGSAGE-217SAGE-217 capsule
DRUGPlaceboSAGE-217 matching placebo capsule

Timeline

Start date
2019-08-06
Primary completion
2020-01-06
Completion
2020-01-06
First posted
2019-07-05
Last updated
2023-11-29
Results posted
2022-10-03

Locations

46 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04007367. Inclusion in this directory is not an endorsement.